One of Uncountably Many Brians
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wholyseedragon.bsky.social
One of Uncountably Many Brians
@wholyseedragon.bsky.social
Desperately seeking Amy.
Reposted by One of Uncountably Many Brians
the antics of heterosexuals are none of my business and the surveillance culture this "scandal" is built on is a dark sign of the times but it is truly wild to put these sentences back to back without your brain backfiring like an old muffler
July 24, 2025 at 5:59 AM
Reposted by One of Uncountably Many Brians
Mitochondrial fusion and cristae reorganization facilitate acquisition of cardiomyocyte identity during reprogramming of murine fibroblasts
Mitochondrial fusion and cristae reorganization facilitate acquisition of cardiomyocyte identity during reprogramming of murine fibroblasts
Spurlock et al. characterize shifts in mitochondrial energetics and morphology during the direct cardiac reprogramming of murine fibroblasts. They show that mitochondrial fusion is required for the acquisition of cardiomyocyte-like identity and identify…
dlvr.it
March 6, 2025 at 3:38 PM
I'm a month late sharing, but I'm pretty proud of this one: We explore how mitochondria change during conversion of cardiac fibroblasts to cardiomyocytes and ID the mito-fission regulator Mtfr1l as a major barrier to reprogramming. Out in @cp-cellreports.bsky.social:
doi.org/10.1016/j.ce...
Mitochondrial fusion and cristae reorganization facilitate acquisition of cardiomyocyte identity during reprogramming of murine fibroblasts - PubMed
Cardiomyocytes (CMs) rely on mitochondrial energy produced in highly interconnected mitochondrial networks. Direct reprogramming of cardiac fibroblasts (CFs) into induced CMs (iCMs) shows promise for ...
pubmed.ncbi.nlm.nih.gov
April 8, 2025 at 5:26 PM
I'm not the best at predictions, but this feels true to me.
I honestly think we are experiencing the end of the internet as those of us born in the 20th c understand it. Smaller, siloed communities like discord servers and newsletters will persist, but the idea of the global public square is dead, as is “the information superhighway.” VCs killed it.
it genuinely sucks that basically nothing on the internet works well anymore. search? barely works. social media? filled with garbage engagement-bait designed to game the algorithm. news websites? pages that refresh at random or so covered in video ads that it’s impossible to read stories
January 9, 2025 at 4:20 PM
Reposted by One of Uncountably Many Brians
Voices of Academia latest blog by Brian Spurlock - Mistakes Were Made: My Experience of Adult ADHD

"One night during my junior year, my mentor called me to let me know that I flooded his lab"

##AcademicMentalHealth

voicesofacademia.com/2024/11/29/m...
November 29, 2024 at 1:34 PM
I reviewed the last 3 years in cardiac reprogramming for Cur Opin in Gen and Dev. My PI said "At first I thought maybe this isn't appropriate for academic writing but then I thought 'iIt's a review! It *should* be interesting!" Read it here: authors.elsevier.com/c/1hsPT,LqAZ...
October 3, 2023 at 1:35 PM