Whitehall II Study
@whitehall2study.bsky.social
The Whitehall II Study @uclbrainscience.bsky.social set up in 1985 to investigate the impact of social class on health, now seeks to investigate quality of life in an ageing cohort.
www.ucl.ac.uk/psychiatry/research/mental-health-older-people/whitehall-ii
www.ucl.ac.uk/psychiatry/research/mental-health-older-people/whitehall-ii
✨New publication!
Assessment of dementia risk scores in predicting mild cognitive impairment: A comparison of CogDrisk, CAIDE, LIBRA, and ANU-ADRI. Huque MH, Anstey KJ. J Prev Alzheimers Dis. 2025 Aug 11:100324. doi: 10.1016/j.tjpad.2025.100324. PMID: 40796458.
pubmed.ncbi.nlm.nih.gov/40796458/
Assessment of dementia risk scores in predicting mild cognitive impairment: A comparison of CogDrisk, CAIDE, LIBRA, and ANU-ADRI. Huque MH, Anstey KJ. J Prev Alzheimers Dis. 2025 Aug 11:100324. doi: 10.1016/j.tjpad.2025.100324. PMID: 40796458.
pubmed.ncbi.nlm.nih.gov/40796458/
September 18, 2025 at 9:30 AM
✨New publication!
Assessment of dementia risk scores in predicting mild cognitive impairment: A comparison of CogDrisk, CAIDE, LIBRA, and ANU-ADRI. Huque MH, Anstey KJ. J Prev Alzheimers Dis. 2025 Aug 11:100324. doi: 10.1016/j.tjpad.2025.100324. PMID: 40796458.
pubmed.ncbi.nlm.nih.gov/40796458/
Assessment of dementia risk scores in predicting mild cognitive impairment: A comparison of CogDrisk, CAIDE, LIBRA, and ANU-ADRI. Huque MH, Anstey KJ. J Prev Alzheimers Dis. 2025 Aug 11:100324. doi: 10.1016/j.tjpad.2025.100324. PMID: 40796458.
pubmed.ncbi.nlm.nih.gov/40796458/
We were delighted to welcome Jens Soeterboek from Maastricht University to today’s Whitehall II group meeting. Despite the backdrop of heavy rain, thunder, and a limited transport network in London, Jens delivered a fascinating presentation on “Exploring Environmental Factors and Brain Health.”
September 11, 2025 at 2:20 PM
We were delighted to welcome Jens Soeterboek from Maastricht University to today’s Whitehall II group meeting. Despite the backdrop of heavy rain, thunder, and a limited transport network in London, Jens delivered a fascinating presentation on “Exploring Environmental Factors and Brain Health.”
🦻Association of midlife hearing impairment and hearing aid use with incident dementia: analysis of two UK-based longitudinal cohort studies 📊
Read more ⬇️
www.nature.com/articles/s43...
Read more ⬇️
www.nature.com/articles/s43...
Association of midlife hearing impairment and hearing aid use with incident dementia: analysis of two UK-based longitudinal cohort studies - Nature Aging
Machado-Fragua et al. report modest associations and population attributable fractions for midlife hearing impairment with dementia, highlighting the need to consider age at measurement of risk factor...
www.nature.com
August 18, 2025 at 2:09 PM
🦻Association of midlife hearing impairment and hearing aid use with incident dementia: analysis of two UK-based longitudinal cohort studies 📊
Read more ⬇️
www.nature.com/articles/s43...
Read more ⬇️
www.nature.com/articles/s43...
Did you know the variables in the Whitehall II datasets are available to search on the CLOSER Discovery platform? CLOSER Discovery is one of the tools produced by @closer-uk.bsky.social . Have a look at our section on CLOSER Discovery (and check out the other studies)!
tinyurl.com/WH2CLSR
tinyurl.com/WH2CLSR
Whitehall II - CLOSER Discovery home page
discovery.closer.ac.uk
August 7, 2025 at 4:09 PM
Did you know the variables in the Whitehall II datasets are available to search on the CLOSER Discovery platform? CLOSER Discovery is one of the tools produced by @closer-uk.bsky.social . Have a look at our section on CLOSER Discovery (and check out the other studies)!
tinyurl.com/WH2CLSR
tinyurl.com/WH2CLSR
Thank you to Monica Iyer from @lshtm.bsky.social for her excellent presentation on "Mental Health Symptoms as Preclinical Signs of Dementia" at the Whitehall II Study meeting this month. It was a delight to host you!
July 24, 2025 at 12:40 PM
Thank you to Monica Iyer from @lshtm.bsky.social for her excellent presentation on "Mental Health Symptoms as Preclinical Signs of Dementia" at the Whitehall II Study meeting this month. It was a delight to host you!
Reposted by Whitehall II Study
New multicohort resource for researchers exploring proteomics in neurodegenerative diseases — including data from the Whitehall II study. 🧠🔬
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The Global Neurodegeneration Proteomics Consortium: biomarker and drug target discovery for common neurodegenerative diseases and aging - Nature Medicine
The largest harmonized proteomic dataset of plasma, serum and cerebrospinal fluid samples across major neurodegenerative diseases reveals both disease-specific and transdiagnostic proteomic signatures...
www.nature.com
July 16, 2025 at 6:03 AM
New multicohort resource for researchers exploring proteomics in neurodegenerative diseases — including data from the Whitehall II study. 🧠🔬
www.nature.com/articles/s41...
www.nature.com/articles/s41...
❓"Which adiposity index is best? Comparison of five indicators and their ability to identify type 2 diabetes risk in a population study"
💓Recent work using Whitehall II data by Prof. Annie Britton and colleagues, published in Diabetes Res. and Clin. Practice
📖 pubmed.ncbi.nlm.nih.gov/40404050/
💓Recent work using Whitehall II data by Prof. Annie Britton and colleagues, published in Diabetes Res. and Clin. Practice
📖 pubmed.ncbi.nlm.nih.gov/40404050/
July 10, 2025 at 10:12 AM
❓"Which adiposity index is best? Comparison of five indicators and their ability to identify type 2 diabetes risk in a population study"
💓Recent work using Whitehall II data by Prof. Annie Britton and colleagues, published in Diabetes Res. and Clin. Practice
📖 pubmed.ncbi.nlm.nih.gov/40404050/
💓Recent work using Whitehall II data by Prof. Annie Britton and colleagues, published in Diabetes Res. and Clin. Practice
📖 pubmed.ncbi.nlm.nih.gov/40404050/
🚨New Whitehall II Imaging Study paper published in BMC Medicine. Findings suggest that maintaining the structural integrity of major arteries may benefit brain health & cognition in later life. @mikakivimaki.bsky.social @sanasuri.bsky.social
📖 Article: bmcmedicine.biomedcentral.com/articles/10....
📖 Article: bmcmedicine.biomedcentral.com/articles/10....
Associations of aortic and carotid artery health with cerebrovascular markers and cognition in older adults from the Whitehall II imaging study - BMC Medicine
Background Cardiovascular disease has been associated with an increased dementia risk, but the underlying mechanisms for this heart-brain link are unclear. This study sought to examine associations be...
bmcmedicine.biomedcentral.com
June 20, 2025 at 3:01 PM
🚨New Whitehall II Imaging Study paper published in BMC Medicine. Findings suggest that maintaining the structural integrity of major arteries may benefit brain health & cognition in later life. @mikakivimaki.bsky.social @sanasuri.bsky.social
📖 Article: bmcmedicine.biomedcentral.com/articles/10....
📖 Article: bmcmedicine.biomedcentral.com/articles/10....
It was a pleasure to celebrate Whitehall II's 40th anniversary this month at UCL with Professor Sir Michael Marmot who set up the study in 1985. Watch the recording of the event here: www.youtube.com/watch?v=__gL...
May 29, 2025 at 11:06 AM
It was a pleasure to celebrate Whitehall II's 40th anniversary this month at UCL with Professor Sir Michael Marmot who set up the study in 1985. Watch the recording of the event here: www.youtube.com/watch?v=__gL...
Whitehall II is 40! We're celebrating on 16th May from 9.45am. Hear from directors Prof Mika Kivimäki & Prof Archana Singh-Manoux, and Whitehall II founder Professor Sir Michael Marmot. Follow our livestream: www.youtube.com/live/HVBzusJ... @mikakivimaki.bsky.social @uclbrainscience.bsky.social
Whitehall II Study 40th Celebration
2025 marks the 40th anniversary of the Whitehall II Study, also known as the Stress and Health Study. To mark the occasion, we will be hosting a morning of talks on the 16th May 2025 at UCL in Blooms...
www.youtube.com
May 7, 2025 at 8:27 AM
Whitehall II is 40! We're celebrating on 16th May from 9.45am. Hear from directors Prof Mika Kivimäki & Prof Archana Singh-Manoux, and Whitehall II founder Professor Sir Michael Marmot. Follow our livestream: www.youtube.com/live/HVBzusJ... @mikakivimaki.bsky.social @uclbrainscience.bsky.social
Reposted by Whitehall II Study
#Ageing is not just about time - it is also shaped by social conditions. In our latest study published in @naturemedicine.bsky.social , we show that social disadvantage is linked to biological ageing @mikakivimaki.bsky.social @uclbrainscience.bsky.social @whitehall2study.bsky.social
March 14, 2025 at 11:16 AM
#Ageing is not just about time - it is also shaped by social conditions. In our latest study published in @naturemedicine.bsky.social , we show that social disadvantage is linked to biological ageing @mikakivimaki.bsky.social @uclbrainscience.bsky.social @whitehall2study.bsky.social
Reposted by Whitehall II Study
Our organs age at different rates, and a blood test determining how much they’ve aged could predict the risk of conditions like lung cancer and heart disease decades later, finds a new study led by Prof Mika Kivimaki @uclbrainscience.bsky.social @whitehall2study.bsky.social
Biological organ ages predict disease risk decades in advance
Our organs age at different rates, and a blood test determining how much they’ve each aged could predict the risk of conditions like lung cancer and heart disease decades later, finds a new study led ...
www.ucl.ac.uk
February 26, 2025 at 4:28 PM
Our organs age at different rates, and a blood test determining how much they’ve aged could predict the risk of conditions like lung cancer and heart disease decades later, finds a new study led by Prof Mika Kivimaki @uclbrainscience.bsky.social @whitehall2study.bsky.social
Our latest publication in the Lancet Digital Health shows that organs age at different rates. Proteomic data from 6235 Whitehall II Study participants revealed that accelerated ageing of specific organs are predictive for over 30 age-related diseases. Link to paper: www.thelancet.com/journals/lan...
Proteomic organ-specific ageing signatures and 20-year risk of age-related diseases: the Whitehall II observational cohort study
Advanced proteomic organ ageing is associated with the long-term risk of age-related
diseases. In most cases, faster ageing of a specific organ increases susceptibility
to morbidity affecting multiple...
www.thelancet.com
February 27, 2025 at 10:27 AM
Our latest publication in the Lancet Digital Health shows that organs age at different rates. Proteomic data from 6235 Whitehall II Study participants revealed that accelerated ageing of specific organs are predictive for over 30 age-related diseases. Link to paper: www.thelancet.com/journals/lan...
Reposted by Whitehall II Study
Protein organ clocks, as assessed in over 6,000 people (~4,000 plasma proteins, 8 organs) with 20-year follow-up are predictive for over 30 age-related diseases
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
February 26, 2025 at 12:10 AM
Protein organ clocks, as assessed in over 6,000 people (~4,000 plasma proteins, 8 organs) with 20-year follow-up are predictive for over 30 age-related diseases
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...