Wes Ely, MD, MPH
@weselymd.bsky.social
Husband & Dad. ICU Doc. Vanderbilt. @CIBScenter studies Covid & Long Covid, ICU Survivorship, Dementia, Delirium, PICS. Fighting misinformation. Posts my own. Still learning.
Reposted by Wes Ely, MD, MPH
Families mourned & Docs Cried on ICU rounds
🔹3 DEATHS in one morning
🔹3 times we did “THE PAUSE”
🔹A voluntary 30-60 sec unscripted bedside silence
🔹Do it for the patient
🔹Do it for yourself
🔹Do it for your team members
Pass it on…The Pause🙏
APP: apple.co/3Cj01qj
🔹3 DEATHS in one morning
🔹3 times we did “THE PAUSE”
🔹A voluntary 30-60 sec unscripted bedside silence
🔹Do it for the patient
🔹Do it for yourself
🔹Do it for your team members
Pass it on…The Pause🙏
APP: apple.co/3Cj01qj
November 16, 2023 at 1:12 PM
Families mourned & Docs Cried on ICU rounds
🔹3 DEATHS in one morning
🔹3 times we did “THE PAUSE”
🔹A voluntary 30-60 sec unscripted bedside silence
🔹Do it for the patient
🔹Do it for yourself
🔹Do it for your team members
Pass it on…The Pause🙏
APP: apple.co/3Cj01qj
🔹3 DEATHS in one morning
🔹3 times we did “THE PAUSE”
🔹A voluntary 30-60 sec unscripted bedside silence
🔹Do it for the patient
🔹Do it for yourself
🔹Do it for your team members
Pass it on…The Pause🙏
APP: apple.co/3Cj01qj
I agree! The Autumn Ghost is an important and enthralling read by Dr. Hannah Wunsch.
Couldn’t put this book down. Just brilliant.
November 16, 2023 at 11:08 PM
I agree! The Autumn Ghost is an important and enthralling read by Dr. Hannah Wunsch.
Reposted by Wes Ely, MD, MPH
Spoke w Amber at @scrippsnews.bsky.social about clinician burnout.
🔥Expect more from your systems and from your leadership.
🔥Know that they won't be enough, you need to care for yourself regardless. Therapy is an amazing resource. Use it.
www.ktvq.com/new-cdc-prog...
🔥Expect more from your systems and from your leadership.
🔥Know that they won't be enough, you need to care for yourself regardless. Therapy is an amazing resource. Use it.
www.ktvq.com/new-cdc-prog...
New CDC program hopes to combat health care worker burnout
The new Impact Wellbeing program provides leadership resources on addressing burnout and encourages hospitals to administer well-being questionnaires.
www.ktvq.com
November 10, 2023 at 11:15 PM
Spoke w Amber at @scrippsnews.bsky.social about clinician burnout.
🔥Expect more from your systems and from your leadership.
🔥Know that they won't be enough, you need to care for yourself regardless. Therapy is an amazing resource. Use it.
www.ktvq.com/new-cdc-prog...
🔥Expect more from your systems and from your leadership.
🔥Know that they won't be enough, you need to care for yourself regardless. Therapy is an amazing resource. Use it.
www.ktvq.com/new-cdc-prog...
Reposted by Wes Ely, MD, MPH
The cover of this week's Lancet and the accompanying article on the UK Covid inquiry by the Editor-in-Chief
thelancet.com/journals/lan...
Imagine if this was done in the United States
thelancet.com/journals/lan...
Imagine if this was done in the United States
November 11, 2023 at 5:00 PM
The cover of this week's Lancet and the accompanying article on the UK Covid inquiry by the Editor-in-Chief
thelancet.com/journals/lan...
Imagine if this was done in the United States
thelancet.com/journals/lan...
Imagine if this was done in the United States
Reposted by Wes Ely, MD, MPH
"I mean, life is a terminal illness. We're all going to die. And for the small slice of time where we're here, we might as well express ourselves and communicate with one another. It has been a blessing beyond blessings for me. It has been a fantastic journey."
My conversation with Bruce Wilkoff a leading cardiologist who dedicated his career to preventing sudden death, now finds a gift in death that he's facing
erictopol.substack.com/p/bruce-wilk...
erictopol.substack.com/p/bruce-wilk...
November 15, 2023 at 4:54 PM
"I mean, life is a terminal illness. We're all going to die. And for the small slice of time where we're here, we might as well express ourselves and communicate with one another. It has been a blessing beyond blessings for me. It has been a fantastic journey."
Families mourned & Docs Cried on ICU rounds
🔹3 DEATHS in one morning
🔹3 times we did “THE PAUSE”
🔹A voluntary 30-60 sec unscripted bedside silence
🔹Do it for the patient
🔹Do it for yourself
🔹Do it for your team members
Pass it on…The Pause🙏
APP: apple.co/3Cj01qj
🔹3 DEATHS in one morning
🔹3 times we did “THE PAUSE”
🔹A voluntary 30-60 sec unscripted bedside silence
🔹Do it for the patient
🔹Do it for yourself
🔹Do it for your team members
Pass it on…The Pause🙏
APP: apple.co/3Cj01qj
November 16, 2023 at 1:12 PM
Families mourned & Docs Cried on ICU rounds
🔹3 DEATHS in one morning
🔹3 times we did “THE PAUSE”
🔹A voluntary 30-60 sec unscripted bedside silence
🔹Do it for the patient
🔹Do it for yourself
🔹Do it for your team members
Pass it on…The Pause🙏
APP: apple.co/3Cj01qj
🔹3 DEATHS in one morning
🔹3 times we did “THE PAUSE”
🔹A voluntary 30-60 sec unscripted bedside silence
🔹Do it for the patient
🔹Do it for yourself
🔹Do it for your team members
Pass it on…The Pause🙏
APP: apple.co/3Cj01qj
Long COVID Disease State
COVID infects us & Interferon causes 3 dastardly plots:
📌 We absorb ⬇️ tryptophan & convert ⬇️ Serotonin
📌 Platelet pathology ⬇️ stores of Serotonin
📌 Vagal nerve signals peripherally ⬆️ impairs brain function & memory
bit.ly/3M5F9ZV
COVID infects us & Interferon causes 3 dastardly plots:
📌 We absorb ⬇️ tryptophan & convert ⬇️ Serotonin
📌 Platelet pathology ⬇️ stores of Serotonin
📌 Vagal nerve signals peripherally ⬆️ impairs brain function & memory
bit.ly/3M5F9ZV
October 17, 2023 at 3:03 PM
Long COVID Disease State
COVID infects us & Interferon causes 3 dastardly plots:
📌 We absorb ⬇️ tryptophan & convert ⬇️ Serotonin
📌 Platelet pathology ⬇️ stores of Serotonin
📌 Vagal nerve signals peripherally ⬆️ impairs brain function & memory
bit.ly/3M5F9ZV
COVID infects us & Interferon causes 3 dastardly plots:
📌 We absorb ⬇️ tryptophan & convert ⬇️ Serotonin
📌 Platelet pathology ⬇️ stores of Serotonin
📌 Vagal nerve signals peripherally ⬆️ impairs brain function & memory
bit.ly/3M5F9ZV
Patients must be heard…Emerging data show post-infectious syndromes like MECFS, Long Covid, Long Lyme, fibromyalgia, and more have pathobiological & psychological components.
Let’s strive toward cultural unity and…
📍Dispel myths
📍Avoid gaslighting
📍Map a path to healing
t.co/nIiC8v3cKc
t.co/nIiC8v3cKc
Long COVID Isn't the Only Post-Viral Illness
Post-viral illnesses are more common than you think—but they got little attention prior to the pandemic
t.co
September 28, 2023 at 2:04 PM
Patients must be heard…Emerging data show post-infectious syndromes like MECFS, Long Covid, Long Lyme, fibromyalgia, and more have pathobiological & psychological components.
Let’s strive toward cultural unity and…
📍Dispel myths
📍Avoid gaslighting
📍Map a path to healing
t.co/nIiC8v3cKc
t.co/nIiC8v3cKc
Everyone deserves a place at the table of #Life‼️
🎈Human Flourishing is a worthy goal
🎈Greg works at the Nashville “Friend’s Life” Treat Truck
🎈@FriendsLifeCom1 works to integrate adults w disabilities into community
Its a model of human flourishing
(pic w perm)
🎈Human Flourishing is a worthy goal
🎈Greg works at the Nashville “Friend’s Life” Treat Truck
🎈@FriendsLifeCom1 works to integrate adults w disabilities into community
Its a model of human flourishing
(pic w perm)
September 8, 2023 at 12:10 PM
Everyone deserves a place at the table of #Life‼️
🎈Human Flourishing is a worthy goal
🎈Greg works at the Nashville “Friend’s Life” Treat Truck
🎈@FriendsLifeCom1 works to integrate adults w disabilities into community
Its a model of human flourishing
(pic w perm)
🎈Human Flourishing is a worthy goal
🎈Greg works at the Nashville “Friend’s Life” Treat Truck
🎈@FriendsLifeCom1 works to integrate adults w disabilities into community
Its a model of human flourishing
(pic w perm)
1/🧵 Long COVID - new @TheLancet data
📌A picture is emerging
📌It’s not pretty
📌Most pts w months-long symptoms aren’t recovered @ 2-yrs
📌The cluster including neurocognitive & cardiovasc symptoms is ominous
📌These data fuel trial design
Thoughts?
bit.ly/3sHrwt9
📌A picture is emerging
📌It’s not pretty
📌Most pts w months-long symptoms aren’t recovered @ 2-yrs
📌The cluster including neurocognitive & cardiovasc symptoms is ominous
📌These data fuel trial design
Thoughts?
bit.ly/3sHrwt9
September 6, 2023 at 12:07 PM
1/🧵 Long COVID - new @TheLancet data
📌A picture is emerging
📌It’s not pretty
📌Most pts w months-long symptoms aren’t recovered @ 2-yrs
📌The cluster including neurocognitive & cardiovasc symptoms is ominous
📌These data fuel trial design
Thoughts?
bit.ly/3sHrwt9
📌A picture is emerging
📌It’s not pretty
📌Most pts w months-long symptoms aren’t recovered @ 2-yrs
📌The cluster including neurocognitive & cardiovasc symptoms is ominous
📌These data fuel trial design
Thoughts?
bit.ly/3sHrwt9
Reposted by Wes Ely, MD, MPH
1st lab assessment of BA.2.86, from Yunlong Cao’s group. Marked immune escape features of this variant, as expected by mutations, but low cell infectivity should dampen transmission potential
This is very good, but still possible BA.2.86 can evolve, pick up new mutations to be more infectious
This is very good, but still possible BA.2.86 can evolve, pick up new mutations to be more infectious
August 31, 2023 at 9:38 PM
1st lab assessment of BA.2.86, from Yunlong Cao’s group. Marked immune escape features of this variant, as expected by mutations, but low cell infectivity should dampen transmission potential
This is very good, but still possible BA.2.86 can evolve, pick up new mutations to be more infectious
This is very good, but still possible BA.2.86 can evolve, pick up new mutations to be more infectious
30 new mutations to #Spike
Keep your loved ones safe from Pirola BA.2.86👇
I’m flying to see Mom. She’s suffering dementia & called to ask if I’d get her “Hair Did.”
“You bet, Mom & we’ll get some great gumbo & shrimp busters”‼️
(new pic w her perm)
bit.ly/3sxkZBf
Keep your loved ones safe from Pirola BA.2.86👇
I’m flying to see Mom. She’s suffering dementia & called to ask if I’d get her “Hair Did.”
“You bet, Mom & we’ll get some great gumbo & shrimp busters”‼️
(new pic w her perm)
bit.ly/3sxkZBf
September 1, 2023 at 1:28 PM
30 new mutations to #Spike
Keep your loved ones safe from Pirola BA.2.86👇
I’m flying to see Mom. She’s suffering dementia & called to ask if I’d get her “Hair Did.”
“You bet, Mom & we’ll get some great gumbo & shrimp busters”‼️
(new pic w her perm)
bit.ly/3sxkZBf
Keep your loved ones safe from Pirola BA.2.86👇
I’m flying to see Mom. She’s suffering dementia & called to ask if I’d get her “Hair Did.”
“You bet, Mom & we’ll get some great gumbo & shrimp busters”‼️
(new pic w her perm)
bit.ly/3sxkZBf
2 recent & important studies on Long COVID
📌Include ~340k COVID patients vs ~7M controls out to 2 yrs
📌Organ dysfunction persists in 33%
📌Levels of disability from #LongCOVID exceed those of cancer & heart dz‼️
Links:
Nature Med - go.nature.com/3OMNfHl
JAMA: bit.ly/45mk8lw
August 28, 2023 at 10:32 PM
2 recent & important studies on Long COVID
📌Include ~340k COVID patients vs ~7M controls out to 2 yrs
📌Organ dysfunction persists in 33%
📌Levels of disability from #LongCOVID exceed those of cancer & heart dz‼️
Links:
Nature Med - go.nature.com/3OMNfHl
JAMA: bit.ly/45mk8lw
Pt w new visual problems.
In ICU, unvaccinated diabetic pt COVID+ and 4+ Staph Sepsis from infected dialysis catheter (now removed). Retinal exam to look for Roth Spots (pic w arrows) & find fluffy white spots…
He’s on COVID tx & anti-Staph ATBs.
1. What else does he have?
2. What should we add?
In ICU, unvaccinated diabetic pt COVID+ and 4+ Staph Sepsis from infected dialysis catheter (now removed). Retinal exam to look for Roth Spots (pic w arrows) & find fluffy white spots…
He’s on COVID tx & anti-Staph ATBs.
1. What else does he have?
2. What should we add?
August 17, 2023 at 2:21 PM
Pt w new visual problems.
In ICU, unvaccinated diabetic pt COVID+ and 4+ Staph Sepsis from infected dialysis catheter (now removed). Retinal exam to look for Roth Spots (pic w arrows) & find fluffy white spots…
He’s on COVID tx & anti-Staph ATBs.
1. What else does he have?
2. What should we add?
In ICU, unvaccinated diabetic pt COVID+ and 4+ Staph Sepsis from infected dialysis catheter (now removed). Retinal exam to look for Roth Spots (pic w arrows) & find fluffy white spots…
He’s on COVID tx & anti-Staph ATBs.
1. What else does he have?
2. What should we add?
Reposted by Wes Ely, MD, MPH
Among over 4.2 million people, Covid was associated with a significant increased risk of developing multiple types of autoimmune diseases compared with uninfected, and vaccination provided protection https://thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00331-0/fulltext
August 16, 2023 at 10:58 PM
Among over 4.2 million people, Covid was associated with a significant increased risk of developing multiple types of autoimmune diseases compared with uninfected, and vaccination provided protection https://thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00331-0/fulltext
Reposted by Wes Ely, MD, MPH
A visit to the doctor in 2023 :-(
August 7, 2023 at 2:23 PM
A visit to the doctor in 2023 :-(
Reading CXRs - pro tips 🏆
Get the most out of your pts CXRs…
You can see my measurements showing a normal VPW on the first which support other data that her SOB was not due to volume overload. The other chest x-ray shows a wide VPW -supported more diuresis & w 2.5 L out he’s much better.
Get the most out of your pts CXRs…
You can see my measurements showing a normal VPW on the first which support other data that her SOB was not due to volume overload. The other chest x-ray shows a wide VPW -supported more diuresis & w 2.5 L out he’s much better.
August 7, 2023 at 12:19 PM
Reading CXRs - pro tips 🏆
Get the most out of your pts CXRs…
You can see my measurements showing a normal VPW on the first which support other data that her SOB was not due to volume overload. The other chest x-ray shows a wide VPW -supported more diuresis & w 2.5 L out he’s much better.
Get the most out of your pts CXRs…
You can see my measurements showing a normal VPW on the first which support other data that her SOB was not due to volume overload. The other chest x-ray shows a wide VPW -supported more diuresis & w 2.5 L out he’s much better.
As a Doctor, I live in a state of Reverence💥
🔹Healing merits my reverence (ie deep respect)
🔹Reverence begets humility
🔹Humility allows me to see her pricelessness & mystery
Once I see her pricelessness, I am in a better place to serve
What do you think of this cascade?
🔹Healing merits my reverence (ie deep respect)
🔹Reverence begets humility
🔹Humility allows me to see her pricelessness & mystery
Once I see her pricelessness, I am in a better place to serve
What do you think of this cascade?
August 7, 2023 at 11:49 AM
As a Doctor, I live in a state of Reverence💥
🔹Healing merits my reverence (ie deep respect)
🔹Reverence begets humility
🔹Humility allows me to see her pricelessness & mystery
Once I see her pricelessness, I am in a better place to serve
What do you think of this cascade?
🔹Healing merits my reverence (ie deep respect)
🔹Reverence begets humility
🔹Humility allows me to see her pricelessness & mystery
Once I see her pricelessness, I am in a better place to serve
What do you think of this cascade?
During COVID, who got “unilateral DNR” orders?
ie, team chose FOR you
📍Black & LatinX – Odds 4-6X
📍Spanish Speaking – Odds 4.5X
📍Covid Pos vs Neg – Odds 8x
Communication barriers ⬆️ vulnerability of having a doc choose EOL plan FOR you.
Is this OK?
Link: bit.ly/44PGWtn
ie, team chose FOR you
📍Black & LatinX – Odds 4-6X
📍Spanish Speaking – Odds 4.5X
📍Covid Pos vs Neg – Odds 8x
Communication barriers ⬆️ vulnerability of having a doc choose EOL plan FOR you.
Is this OK?
Link: bit.ly/44PGWtn
August 3, 2023 at 12:05 PM
During COVID, who got “unilateral DNR” orders?
ie, team chose FOR you
📍Black & LatinX – Odds 4-6X
📍Spanish Speaking – Odds 4.5X
📍Covid Pos vs Neg – Odds 8x
Communication barriers ⬆️ vulnerability of having a doc choose EOL plan FOR you.
Is this OK?
Link: bit.ly/44PGWtn
ie, team chose FOR you
📍Black & LatinX – Odds 4-6X
📍Spanish Speaking – Odds 4.5X
📍Covid Pos vs Neg – Odds 8x
Communication barriers ⬆️ vulnerability of having a doc choose EOL plan FOR you.
Is this OK?
Link: bit.ly/44PGWtn
Real Suffering: Long COVID
We need to discover scientific answers & medical treatments
In our recent Neuro LongCOVID paper
Link: https://bit.ly/458yuW2
With permission we present this husband, firefighter, EMT who developed mild acute COVID-19 in 2021 & now has long COVID w bilateral hearing aids
We need to discover scientific answers & medical treatments
In our recent Neuro LongCOVID paper
Link: https://bit.ly/458yuW2
With permission we present this husband, firefighter, EMT who developed mild acute COVID-19 in 2021 & now has long COVID w bilateral hearing aids
August 2, 2023 at 1:40 PM
Real Suffering: Long COVID
We need to discover scientific answers & medical treatments
In our recent Neuro LongCOVID paper
Link: https://bit.ly/458yuW2
With permission we present this husband, firefighter, EMT who developed mild acute COVID-19 in 2021 & now has long COVID w bilateral hearing aids
We need to discover scientific answers & medical treatments
In our recent Neuro LongCOVID paper
Link: https://bit.ly/458yuW2
With permission we present this husband, firefighter, EMT who developed mild acute COVID-19 in 2021 & now has long COVID w bilateral hearing aids
On Acceptance💥
This weekend we went to a wedding. Of 200+ people, guess who had the best time & why?
It was Greg (my brother-in-law, pic w his perm). He ACCEPTS life on life’s terms better than anyone I’ve ever met.
What’s your TOP TAKE HOME about Acceptance?
This weekend we went to a wedding. Of 200+ people, guess who had the best time & why?
It was Greg (my brother-in-law, pic w his perm). He ACCEPTS life on life’s terms better than anyone I’ve ever met.
What’s your TOP TAKE HOME about Acceptance?
August 2, 2023 at 12:21 PM
On Acceptance💥
This weekend we went to a wedding. Of 200+ people, guess who had the best time & why?
It was Greg (my brother-in-law, pic w his perm). He ACCEPTS life on life’s terms better than anyone I’ve ever met.
What’s your TOP TAKE HOME about Acceptance?
This weekend we went to a wedding. Of 200+ people, guess who had the best time & why?
It was Greg (my brother-in-law, pic w his perm). He ACCEPTS life on life’s terms better than anyone I’ve ever met.
What’s your TOP TAKE HOME about Acceptance?
Reposted by Wes Ely, MD, MPH
An important NEJM editorial by HHS Secretary Becerra and
Ashish Jha on Project NextGen 🧪
—"our fight against SARS-CoV-2 is not over"
—"$5 billion investment will focus on 3 main areas" better, variant-proof, pan-sarbecovirus vaccines; mucosal (nasal) vaccines; and monoclonal antibodies
Ashish Jha on Project NextGen 🧪
—"our fight against SARS-CoV-2 is not over"
—"$5 billion investment will focus on 3 main areas" better, variant-proof, pan-sarbecovirus vaccines; mucosal (nasal) vaccines; and monoclonal antibodies
July 26, 2023 at 9:06 PM
An important NEJM editorial by HHS Secretary Becerra and
Ashish Jha on Project NextGen 🧪
—"our fight against SARS-CoV-2 is not over"
—"$5 billion investment will focus on 3 main areas" better, variant-proof, pan-sarbecovirus vaccines; mucosal (nasal) vaccines; and monoclonal antibodies
Ashish Jha on Project NextGen 🧪
—"our fight against SARS-CoV-2 is not over"
—"$5 billion investment will focus on 3 main areas" better, variant-proof, pan-sarbecovirus vaccines; mucosal (nasal) vaccines; and monoclonal antibodies
Reposted by Wes Ely, MD, MPH
Important oped by my colleague Julia Moore-Vogel on the pressing need to find treatments for Long Covid
https://www.latimes.com/opinion/story/2023-07-31/long-covid-prevalence-research-treatments
https://www.latimes.com/opinion/story/2023-07-31/long-covid-prevalence-research-treatments
July 31, 2023 at 4:02 PM
Important oped by my colleague Julia Moore-Vogel on the pressing need to find treatments for Long Covid
https://www.latimes.com/opinion/story/2023-07-31/long-covid-prevalence-research-treatments
https://www.latimes.com/opinion/story/2023-07-31/long-covid-prevalence-research-treatments
Do NOT “Ignore” COVID
@BostonGlobe Published an overly confident Headline
Highlights from @ashishkjha:
📍Paxlovid helps prevent severe COVID
📍Vaccines reduce longCOVID
📍Wear N95 masks indoors
📍The virus continues to evolve - be smart‼️
https://bit.ly/3QiOJvu
@BostonGlobe Published an overly confident Headline
Highlights from @ashishkjha:
📍Paxlovid helps prevent severe COVID
📍Vaccines reduce longCOVID
📍Wear N95 masks indoors
📍The virus continues to evolve - be smart‼️
https://bit.ly/3QiOJvu
With a few basic steps, most of us can finally ignore COVID - The Boston Globe
People who are up-to-date on their vaccines and get treated when infected rarely get seriously ill.
bit.ly
August 1, 2023 at 12:04 PM
Do NOT “Ignore” COVID
@BostonGlobe Published an overly confident Headline
Highlights from @ashishkjha:
📍Paxlovid helps prevent severe COVID
📍Vaccines reduce longCOVID
📍Wear N95 masks indoors
📍The virus continues to evolve - be smart‼️
https://bit.ly/3QiOJvu
@BostonGlobe Published an overly confident Headline
Highlights from @ashishkjha:
📍Paxlovid helps prevent severe COVID
📍Vaccines reduce longCOVID
📍Wear N95 masks indoors
📍The virus continues to evolve - be smart‼️
https://bit.ly/3QiOJvu