Wen-Cong Huang
@wentsunghwang.bsky.social
PhD candidate @anja1.bsky.social group @NIOZ and @UvA 🇳🇱. Interested in molecular evolution, Archaea and cell biology. https://w-huang.com
My apologies to the authors. I tried tagging you, but it kept getting marked as spam… which ironically turned it into real spam.
November 13, 2025 at 7:35 PM
My apologies to the authors. I tried tagging you, but it kept getting marked as spam… which ironically turned it into real spam.
This project is done with @ndombrowski.bsky.social , @tmahendrarajah.bsky.social , Noah Wahl, @stamatak.bsky.social , @ssolo.bsky.social , @tweethinking.bsky.social and @anja1.bsky.social.
November 13, 2025 at 7:28 PM
This project is done with @ndombrowski.bsky.social , @tmahendrarajah.bsky.social , Noah Wahl, @stamatak.bsky.social , @ssolo.bsky.social , @tweethinking.bsky.social and @anja1.bsky.social.
We also recovered the DPANN as the sister group to TACK and Asgard archaea and suggest that their genome evolution has been characterised by episodes of genome streamlining and expansion, driven by gene loss and transfer.
November 13, 2025 at 7:28 PM
We also recovered the DPANN as the sister group to TACK and Asgard archaea and suggest that their genome evolution has been characterised by episodes of genome streamlining and expansion, driven by gene loss and transfer.
Our analyses converge on a narrow archaeal root region at/near the base of the Euryarchaeota, supporting hypotheses in which the Last Archaeal Common Ancestor was a complex, free-living (hyper-)thermophilic methanogen.
November 13, 2025 at 7:28 PM
Our analyses converge on a narrow archaeal root region at/near the base of the Euryarchaeota, supporting hypotheses in which the Last Archaeal Common Ancestor was a complex, free-living (hyper-)thermophilic methanogen.
In this project, we investigated the root of Archaea using a range of phylogenetic approaches, including the best available site- and branch-heterogeneous substitution models, and new gene tree-species tree reconciliation models.
doi.org/10.1093/bioi...
doi.org/10.1093/bioi...
AleRax: a tool for gene and species tree co-estimation and reconciliation under a probabilistic model of gene duplication, transfer, and loss
AbstractMotivation. Genomes are a rich source of information on the pattern and process of evolution across biological scales. How best to make use of that
doi.org
November 13, 2025 at 7:28 PM
In this project, we investigated the root of Archaea using a range of phylogenetic approaches, including the best available site- and branch-heterogeneous substitution models, and new gene tree-species tree reconciliation models.
doi.org/10.1093/bioi...
doi.org/10.1093/bioi...
Authors: @anja1.bsky.social , @tweethinking.bsky.social, @chrisrinke.bsky.social, @ettema.bsky.social, @ssolo.bsky.social, @Lénárd Szánthó, @Zheng-Shuang Hua, @Maraike Probst
August 14, 2025 at 7:28 PM
Authors: @anja1.bsky.social , @tweethinking.bsky.social, @chrisrinke.bsky.social, @ettema.bsky.social, @ssolo.bsky.social, @Lénárd Szánthó, @Zheng-Shuang Hua, @Maraike Probst
Deep origin of eukaryotes outside Heimdallarchaeia within Asgardarchaeota
www.nature.com/articles/s41...
This paper is interesting, and provides evidence that several Njordarchaeales genomes were contaminated by TACK genomes.
But from the peer review file, don't do this. Ignorance is not a virtue:
www.nature.com/articles/s41...
This paper is interesting, and provides evidence that several Njordarchaeales genomes were contaminated by TACK genomes.
But from the peer review file, don't do this. Ignorance is not a virtue:
May 23, 2025 at 10:19 AM
4/ 🧵 This project is with @anja1.bsky.social, @tweethinking.bsky.social, @ssolo.bsky.social , @ettema.bsky.social,@chrisrinke.bsky.social, Zheng-Shuang Hua Maraike Probst and Lenard Szantho.
May 23, 2025 at 10:19 AM
4/ 🧵 This project is with @anja1.bsky.social, @tweethinking.bsky.social, @ssolo.bsky.social , @ettema.bsky.social,@chrisrinke.bsky.social, Zheng-Shuang Hua Maraike Probst and Lenard Szantho.
3/ 🧵 but challenging to place due to compositional heterogeneity, in line with Eme et al, 2023 (branch-wise or site-wise)....
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes - Nature
Analyses of multiple phylogenetic marker datasets of Asgard archaea provide insight into the transition from prokaryotes to eukaryotes, specifically placing eukaryotes within Asgard archaea and as a s...
www.nature.com
May 23, 2025 at 10:19 AM
3/ 🧵 but challenging to place due to compositional heterogeneity, in line with Eme et al, 2023 (branch-wise or site-wise)....
www.nature.com/articles/s41...
www.nature.com/articles/s41...
2/ 🧵 that conflicting signals exist even within the same contigs but become more consistent with better fitting models. Using the best available model, our analyses suggest that the Pangui-Njordarchaeales are indeed members of the Asgard archaea
May 23, 2025 at 10:19 AM
2/ 🧵 that conflicting signals exist even within the same contigs but become more consistent with better fitting models. Using the best available model, our analyses suggest that the Pangui-Njordarchaeales are indeed members of the Asgard archaea