Vikram Thimaradka
@vthi.bsky.social
Postdoctoral Research fellow MGB/Broad Institute. Ph.D. @KyotoUniv. Chemical biology, Induced Proximity, Therapeutics.
Reposted by Vikram Thimaradka
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers https://covalentmodifiers.blogspot.com/2025/02/iscovery-of-elironrasib-rmc-6291-potent.html
February 26, 2025 at 5:00 AM
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers https://covalentmodifiers.blogspot.com/2025/02/iscovery-of-elironrasib-rmc-6291-potent.html
Reposted by Vikram Thimaradka
Comprehensive coverage of spatial proteomics in The Scientist, highlighting how deep visual proteomics is advancing our understanding of disease. Great to share our perspective alongside another pioneer in the field!
www.the-scientist.com/spatial-prot...
www.the-scientist.com/spatial-prot...
Spatial Proteomics and Deep Visual Proteomics: A Revolution in Cell Biology
Spatial proteomics creates detailed protein profiles of cells. This article covers spatial proteomics methods, deep visual proteomics, and their applications.
www.the-scientist.com
February 24, 2025 at 1:30 PM
Comprehensive coverage of spatial proteomics in The Scientist, highlighting how deep visual proteomics is advancing our understanding of disease. Great to share our perspective alongside another pioneer in the field!
www.the-scientist.com/spatial-prot...
www.the-scientist.com/spatial-prot...
Reposted by Vikram Thimaradka
What an amazing discovery from Scott Kennedy's lab! A new splicing system that recognizes transposons and removes them from mRNAs! t.co/3p3wyxkYXX
https://www.biorxiv.org/content/10.1101/2025.02.14.638102v1?ct=
t.co
February 18, 2025 at 2:51 PM
What an amazing discovery from Scott Kennedy's lab! A new splicing system that recognizes transposons and removes them from mRNAs! t.co/3p3wyxkYXX
Reposted by Vikram Thimaradka
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.
February 8, 2025 at 9:21 PM
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.