Vojtech Dvorak
@vojtechdvorak.bsky.social
Chemical biologist & drug hunter, keen on membrane transporters and metabolism
Reposted by Vojtech Dvorak
OBS SPEAKER HIGHLIGHT👩🔬
How Skin Injury Primes Distant Immunity
🗣️ @mariemradhouani.bsky.social
@starkllab.bsky.social lab.bsky.social
@cemm-vienna.bsky.social @meduniwien.ac.at
📆 Thu, June 5, 11 pm ET
👉 Registration:
us02web.zoom.us/meeting/regi...
How Skin Injury Primes Distant Immunity
🗣️ @mariemradhouani.bsky.social
@starkllab.bsky.social lab.bsky.social
@cemm-vienna.bsky.social @meduniwien.ac.at
📆 Thu, June 5, 11 pm ET
👉 Registration:
us02web.zoom.us/meeting/regi...
June 2, 2025 at 11:28 AM
OBS SPEAKER HIGHLIGHT👩🔬
How Skin Injury Primes Distant Immunity
🗣️ @mariemradhouani.bsky.social
@starkllab.bsky.social lab.bsky.social
@cemm-vienna.bsky.social @meduniwien.ac.at
📆 Thu, June 5, 11 pm ET
👉 Registration:
us02web.zoom.us/meeting/regi...
How Skin Injury Primes Distant Immunity
🗣️ @mariemradhouani.bsky.social
@starkllab.bsky.social lab.bsky.social
@cemm-vienna.bsky.social @meduniwien.ac.at
📆 Thu, June 5, 11 pm ET
👉 Registration:
us02web.zoom.us/meeting/regi...
Even though this essay is supposedly a classic, I only discovered it a few days ago. It’s a great (short) read, indeed!
www.cell.com/cancer-cell/...
www.cell.com/cancer-cell/...
Can a biologist fix a radio?—Or, what I learned while studying apoptosis
As a freshly minted Assistant Professor, I feared that everything in my field would
be discovered before I even had a chance to set up my laboratory. Indeed, the field
of apoptosis, which I had recent...
www.cell.com
May 25, 2025 at 6:38 AM
Even though this essay is supposedly a classic, I only discovered it a few days ago. It’s a great (short) read, indeed!
www.cell.com/cancer-cell/...
www.cell.com/cancer-cell/...
Reposted by Vojtech Dvorak
Paper(s) alert from our RESOLUTE project – In a compilation of four papers in @molsystbiol.org we show how we were deciphering cellular logistics and present a comprehensive systematic blueprint of chemical transport pathways with #SoluteCarrier transporters
May 19, 2025 at 10:46 AM
Paper(s) alert from our RESOLUTE project – In a compilation of four papers in @molsystbiol.org we show how we were deciphering cellular logistics and present a comprehensive systematic blueprint of chemical transport pathways with #SoluteCarrier transporters
Reposted by Vojtech Dvorak
Want to know how the ligands interact with proteins beyond model cell lines, e.g., in tissues or bacteria? Interested in membrane targets? Check out our High-Throughput PELSA method which allows you do all these cool screenings for dozens of ligands within two hours! www.biorxiv.org/content/10.1...
High-throughput peptide-centric local stability assay extends protein-ligand identification to membrane proteins, tissues, and bacteria
Systematic mapping of protein-ligand interactions is essential for understanding biological processes and drug mechanisms. Peptide-centric local stability assay (PELSA) is a powerful tool for detectin...
www.biorxiv.org
April 29, 2025 at 6:13 PM
Want to know how the ligands interact with proteins beyond model cell lines, e.g., in tissues or bacteria? Interested in membrane targets? Check out our High-Throughput PELSA method which allows you do all these cool screenings for dozens of ligands within two hours! www.biorxiv.org/content/10.1...
Reposted by Vojtech Dvorak
I'm excited to share my first-author PhD paper, now out in Science Immunology! @science.org
We show that S.aureus skin infection leaves a lasting imprint on bone marrow eosinophils, fueling allergic responses in the lungs.
📄 Read the full study: www.science.org/doi/10.1126/...
Let’s dive in 🧵 1/9
We show that S.aureus skin infection leaves a lasting imprint on bone marrow eosinophils, fueling allergic responses in the lungs.
📄 Read the full study: www.science.org/doi/10.1126/...
Let’s dive in 🧵 1/9
Eosinophil innate immune memory after bacterial skin infection promotes allergic lung inflammation
Staphylococcus aureus skin infection induces eosinophil innate immune memory to exacerbate allergen-induced airway inflammation.
www.science.org
April 4, 2025 at 6:18 PM
I'm excited to share my first-author PhD paper, now out in Science Immunology! @science.org
We show that S.aureus skin infection leaves a lasting imprint on bone marrow eosinophils, fueling allergic responses in the lungs.
📄 Read the full study: www.science.org/doi/10.1126/...
Let’s dive in 🧵 1/9
We show that S.aureus skin infection leaves a lasting imprint on bone marrow eosinophils, fueling allergic responses in the lungs.
📄 Read the full study: www.science.org/doi/10.1126/...
Let’s dive in 🧵 1/9
Reposted by Vojtech Dvorak
Lactate homeostasis is maintained through regulation of glycolysis and lipolysis: Cell Metabolism www.cell.com/cell-metabol...
Lactate homeostasis is maintained through regulation of glycolysis and lipolysis
Lactate elevations are a hallmark of human disease, but the mechanisms regulating
lactate levels remain poorly understood. Here, Lee et al. elucidate the mechanisms
of lactate homeostasis. These invol...
www.cell.com
February 1, 2025 at 4:13 PM
Lactate homeostasis is maintained through regulation of glycolysis and lipolysis: Cell Metabolism www.cell.com/cell-metabol...
Reposted by Vojtech Dvorak
🔬 Calling all PhD students & postdocs in chemistry/biology!
Join us at the Chemical Probes Hackathon 🧪:
🗓️ Feb 20, 2025 | 10:00–14:30
📍 Vienna, Austria
💡 Evaluate chemical probes w/ experts & improve global science 🌍.
🎓 Earn a Certificate of Attendance!
Learn more & register 👇
Join us at the Chemical Probes Hackathon 🧪:
🗓️ Feb 20, 2025 | 10:00–14:30
📍 Vienna, Austria
💡 Evaluate chemical probes w/ experts & improve global science 🌍.
🎓 Earn a Certificate of Attendance!
Learn more & register 👇
January 28, 2025 at 9:29 AM
🔬 Calling all PhD students & postdocs in chemistry/biology!
Join us at the Chemical Probes Hackathon 🧪:
🗓️ Feb 20, 2025 | 10:00–14:30
📍 Vienna, Austria
💡 Evaluate chemical probes w/ experts & improve global science 🌍.
🎓 Earn a Certificate of Attendance!
Learn more & register 👇
Join us at the Chemical Probes Hackathon 🧪:
🗓️ Feb 20, 2025 | 10:00–14:30
📍 Vienna, Austria
💡 Evaluate chemical probes w/ experts & improve global science 🌍.
🎓 Earn a Certificate of Attendance!
Learn more & register 👇
Reposted by Vojtech Dvorak
Kicking off the new year: A collaboration between @giuliosupertifurga.bsky.social and @alessiociulli.bsky.social using a transporter-focused genetic screens revealed that the efflux pump ABCC1/MRP1 restricts PROTAC sensitivity in cancer cells. Out now in @CellChemBiol www.cell.com/cell-chemica...
January 7, 2025 at 7:28 AM
Kicking off the new year: A collaboration between @giuliosupertifurga.bsky.social and @alessiociulli.bsky.social using a transporter-focused genetic screens revealed that the efflux pump ABCC1/MRP1 restricts PROTAC sensitivity in cancer cells. Out now in @CellChemBiol www.cell.com/cell-chemica...