Ville Paavilainen
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villepaavilainen.bsky.social
Ville Paavilainen
@villepaavilainen.bsky.social
Group leader at the Institute of Biotechnology at the University of Helsinki. My lab studies natural product small molecules that modulate protein secretion.
Congrats to everyone!
November 7, 2025 at 2:46 PM
Congrats all!
November 6, 2025 at 3:39 PM
Great work, I just only managed to read your paper! Many more details to be discovered in ER protein insertion and nice to see good alignment with the metazoan TRAP structures..
November 4, 2025 at 9:56 AM
Wonderful news, I remember you writing this proposal at an airport going to meeting, congrats all!
November 4, 2025 at 7:20 AM
Thanks for the tips. I will try the downsampling and trying different resolution ranges was what I was thinking as well. I barely see some of the TMs within the micelle in 2D and there is not much outside the membrane region. Your method allowed seeing most of the TMs so progress..
September 23, 2025 at 11:27 AM
Hi Oli,
Thanks for posting this and the preprint! We tried your method for a small membrane protein and definitely saw an improvement, but not a complete breakthrough yet. Can you comment about limitations of this method for membrane proteins?
September 23, 2025 at 6:44 AM
Congrats to all the organizers of this wonderful event. Great to see the next generation of proteostasis scientists as well as the old friends in this picture!
September 19, 2025 at 12:49 PM
Congrats everyone, really nice insights into rRNA methylation in mitochondria and what a cool approach!
June 30, 2025 at 12:17 PM
Congrats Markku and we look forward to starting your research program here!
June 23, 2025 at 2:55 PM