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viennaairwaylab.bsky.social
Vienna Airway Lab
@viennaairwaylab.bsky.social
Immunology | Allergology | Type 2 Inflammation | Chronic Rhinosinusitis

🌐 viairlab.com
📷 instagram.com/viairlab
🔬 Run by dedicated Lab Members 🇦🇹 🇬🇧 🇪🇹 🇸🇾 🇬🇷 🇨🇳🇪‌🇱‌ 🏳️‍🌈
Aberrant ceramide accumulation fuels eosinophilic inflammation by promoting Eosinophil Extracellular Traps (EET) formation and release in Chronic rhinosinusitis with nasal polyps (CRSwNP)
#CRSwNP #inflammation #ROS #oxidativestress

🔗 ino.to/hBsxjbm
November 25, 2025 at 7:17 AM
Review highlights the role of NRF2 signalling in chronic obstructive pulmonary disease: regulation of #ferroptosis and therapeutic implications 💊
#Immunology #redox #NRF2 #COPD

🔗 ino.to/P4uko9Z
November 18, 2025 at 7:03 AM
New research reveals a hidden link between systemic and gut immunity, showing that affinity-matured IgA in the gut can be generated from IgG1 cells, a pathway that could be key for designing effective mucosal vaccines.
#Immunology #vaccines

🔗 doi.org/10.1016/j.im...
November 18, 2025 at 6:56 AM
Beyond its beautiful, segmented shape 🔬, the #neutrophil nucleus may be a key to understanding immune cell migration and gene regulation - but its full functional relevance remains unknown.

#Immunology #ImmunoSky #CellBiology

🔗 ino.to/bQiWo2g
November 13, 2025 at 7:06 PM
In severe asthma, type 2 cytokines (IL-5/IL-4) drive harmful eosinophil inflammation. A multi-omics study shows all-trans retinoic acid (ATRA) counteracts this and maintains eosinophil homeostasis, offering novel insights and therapeutic hopes.

#Immunology #asthma #type2

🔗 doi.org/10.1016/j.ja...
November 11, 2025 at 8:24 AM
📣 Join our webinar 🖥️ today to hear about biomarkers 🧬 of #NRF2 activation and their role in fighting chronic diseases 💊

@benbedphar.bsky.social
#BenBedPhar #COST #NRF2 #redox

🔗 www.antiox.it/webinars2025...
October 28, 2025 at 6:19 AM
📚 Our new review is out! @benbedphar.bsky.social WG3 dives deep into measuring #NRF2 activity across diseases and how to translate these biomarkers into clinical practice for better patient care.
Massive thanks to the fantastic team behind this work! 🙌
#NCD #COST #stress

🔗 doi.org/10.1016/j.re...
October 14, 2025 at 7:46 AM
Great to be part of the United Airways Symposium in Linz!
I spoke about “Epithelium as the starting point of inflammation in the upper and lower respiratory tract.”
Thanks to Prof. Lamprecht and AstraZeneca for a well-organized and inspiring event.
#UnitedAirways #medsky #medunivienna
October 13, 2025 at 6:23 AM
A fantastic finale at Kadir Has Istanbul for the #BenBedPhar MC&Scientific Meeting. Delivered WG3 report, presented our new research, and chaired #NRF2 scientific session. Grateful for an incredible 4 years with this brilliant #COST Action community—a truly unique journey 🎉
@benbedphar.bsky.social
October 11, 2025 at 2:10 PM
More highlights from the ENT Congress 🇦🇹

Our team contributed across many areas:
🔬 Christina on machine learning in CRS
🤧 Mo on allergies in the upper airway
🧬 Linda on oxidative stress & NRF2 signaling
💡 Sven in clinical dialogue & interactive sessions

#ENT #Allergy #Science #Medicine #Research
September 19, 2025 at 1:16 PM
🇦🇹 First highlight from the Austrian ENT Conference: Vienna Airway Lab!

✨ Tina Bartosik gave a talk in the Allergology session on “Indicating Biologicals – What Role Do Allergies Play?”

🏆 Sven Schneider was elected Chair of the Working Group on Rhinology and Skull Base Surgery.

#ENT #Immunosky
September 18, 2025 at 9:38 AM
🎥 CRS Research in Focus
Christina Morgenstern breaks down her latest study on chronic rhinosinusitis in a short, easy-to-follow video.

📲 Scan the QR code to watch the full video and get a quick overview of the research!
#Immunosky #Medsky
September 18, 2025 at 8:50 AM
🎉 Our new paper on proteomic signatures 🧪 and Machine Learning 🖥️ defining Chronic Rhinosinusitis (#CRS) endotypes 👃 is now published in JACI! Dive into the deep science or enjoy the fantastic comic version by Sara Miranda.
#Proteomics #AI #ML #biomarker #Immunology #SciComm

🔗 tinyurl.com/d5eup39j
September 11, 2025 at 3:00 PM
Excellent review summarizes the current evidence on omics studies in NSAID‐Exacerbated Respiratory Disease (N-ERD). A systems-level understanding of #N-ERD is definitely necessary to identify biomarkers and novel therapies 💊 for this debilitating disease.

##CRS #omics #ImmunoSky

🔗 ino.to/hiZcmXM
September 9, 2025 at 6:41 AM
Exciting research on explainable artificial intelligence for predicting inflammatory signatures and spatial molecular heterogeneity from nasal polyp histology.

#CRSwNP #Immunology #AI

🔗 www.jacionline.org/article/S009...
September 2, 2025 at 6:59 AM
Excited to be on my Short-term Scientific Mission at @uniuef.bsky.social in beautiful Kuopio 🇫🇮! Huge thanks to Prof. Katja Kanninen and her team for hosting. Gaining valuable experience for #CRS #biomarker research 🧪
Grateful to #COST action @benbedphar.bsky.social for this opportunity! 🌍
August 27, 2025 at 7:15 PM
Amazing week at IUIS 2025 in Vienna 🌍☀️ Inspiring science, great people, and fun times! Highlights: Mo Zghaebi’s talk 👏, Christina Morgenstern winning the Immunology Run 🏅, and the legendary Prater Dome party 🪩🎶
#IUIS2025 #Immunology #MedUniWien
August 26, 2025 at 5:32 AM
#IUIS2025 opened in Vienna with music, dance & the motto “Waltzing into the Future of Immunology.” 🎶🧬

You can meet us here:

Mo Zghaebi – IgE B cell recall (Wed 11:34, Hall 2)

Christina Morgenstern – CRS biomarkers (Poster I.283)

Fana Kidane – B cell signatures in CRS & AR (Poster I.014)
August 18, 2025 at 4:18 PM
Word!
And for the horrendous price of publishing in their esteemed journal they even miss a typo in the Abstract!
It´s all very disappointing
August 12, 2025 at 11:22 AM
I´m sure it´s a great paper but a typo in the abstract spoils my reading pleasure 🙄
Why do we even bother with peer-reviewing?
#academia
🧪
August 11, 2025 at 10:14 AM
And we're thrilled we'll have it up and running soon in AKH Vienna and @meduniwien.ac.at 🎉! Better diagnostics, less discomfort—let’s go! 🙌 #MedSky #Immunosky
July 14, 2025 at 8:18 AM
Just toured our future lab in the almost finished Anna Spiegel II building at MedUni Vienna! 🚧🔬 Excited to move out of windowless labs and into a bright, collaborative space later this year. Big things ahead for airway research! ☀️🧬 #ViennaAirwayLab #AnnaSpiegelII #MedUniVienna #Research
July 10, 2025 at 5:24 AM
Study reveals a subgroup of T2-high asthma patients on anti-IL5 biologics have worse control & persistent non-T2 inflammation (neutrophil activity/alarmins), identifying an untapped treatment target for severe asthma. 🔬
#Asthma #Biologics #Immunology #ImmunoSky

🔗 doi.org/10.1016/j.ja...
July 1, 2025 at 4:05 AM
Great few days at #ERS2025 in Budapest! Vienna Airway Lab shared work on Chronic rhinosinusitis biomarkers + tissue remodeling. Big thanks to the organizers — great talks, great crowd, great science. 👃🧬💬
#MedUniVienna #CRS
June 30, 2025 at 6:32 AM
A potential new immune checkpoint: The KEAP1-NRF2 pathway drives PTGIR expression, inducing CD8+ T cell exhaustion via metabolic changes. Blocking PTGIR enhances T cell function, pointing to alternative immunotherapy targets 💊.

#NRF2 #Immunology #ImmunoSky

🔗 rdcu.be/etTbI
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June 28, 2025 at 2:17 PM