Viktoriia Huryn
@vhuryn.bsky.social
she/them
HEiBRIDS PhD candidate at Max-Delbrück-Center, Berlin
Computational Biology and Machine Learning
Kindness and freedom 🇺🇦 🇵🇸
All opinions are my own
HEiBRIDS PhD candidate at Max-Delbrück-Center, Berlin
Computational Biology and Machine Learning
Kindness and freedom 🇺🇦 🇵🇸
All opinions are my own
Reposted by Viktoriia Huryn
To evaluate computational models, we rely on trusted benchmark data and metrics
So what if a metrics is widely used… but plain wrong? It means that evaluations in dozens of papers are meaningless.
This has happened in single cell genomics…
(1/)
So what if a metrics is widely used… but plain wrong? It means that evaluations in dozens of papers are meaningless.
This has happened in single cell genomics…
(1/)
Shortcomings of silhouette in single-cell integration benchmarking - @uweohler.bsky.social @prauten.bsky.social @mdc-bimsb.bsky.social @mdc-berlin.bsky.social @humboldtuni.bsky.social go.nature.com/4fcQzZr
Shortcomings of silhouette in single-cell integration benchmarking - Nature Biotechnology
Silhouette score is unsuitable as a metric for single-cell data integration.
go.nature.com
August 6, 2025 at 8:07 AM
To evaluate computational models, we rely on trusted benchmark data and metrics
So what if a metrics is widely used… but plain wrong? It means that evaluations in dozens of papers are meaningless.
This has happened in single cell genomics…
(1/)
So what if a metrics is widely used… but plain wrong? It means that evaluations in dozens of papers are meaningless.
This has happened in single cell genomics…
(1/)
Reposted by Viktoriia Huryn
1/4 🧵 Preprint alert: In "Metrics Matter: Why We Need to Stop Using Silhouette in #SingleCell #Benchmarking," we reveal critical flaws in common #Evaluation metrics for #Integration and propose robust alternatives. @uweohler.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Metrics Matter: Why We Need to Stop Using Silhouette in Single-Cell Benchmarking
Current-day single-cell studies comprise complex data sets affected by nested batch effects caused by technical and biological factors, relying on advanced integration methods. Silhouette is an establ...
www.biorxiv.org
January 24, 2025 at 5:49 PM
1/4 🧵 Preprint alert: In "Metrics Matter: Why We Need to Stop Using Silhouette in #SingleCell #Benchmarking," we reveal critical flaws in common #Evaluation metrics for #Integration and propose robust alternatives. @uweohler.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Viktoriia Huryn
We are now accepting applications for the spring round of our fully-funded #PhD positions at @mdc-berlin.bsky.social‼️
Apply for your #ScienceCareer in:
▶️ Genes, Cells and Cell-based Medicine
▶️ Molecular Processes and Therapies
▶️ Integrative Biomedicine
👉 www.mdc-berlin.de/phd 👈
Apply for your #ScienceCareer in:
▶️ Genes, Cells and Cell-based Medicine
▶️ Molecular Processes and Therapies
▶️ Integrative Biomedicine
👉 www.mdc-berlin.de/phd 👈
December 18, 2024 at 12:00 PM
We are now accepting applications for the spring round of our fully-funded #PhD positions at @mdc-berlin.bsky.social‼️
Apply for your #ScienceCareer in:
▶️ Genes, Cells and Cell-based Medicine
▶️ Molecular Processes and Therapies
▶️ Integrative Biomedicine
👉 www.mdc-berlin.de/phd 👈
Apply for your #ScienceCareer in:
▶️ Genes, Cells and Cell-based Medicine
▶️ Molecular Processes and Therapies
▶️ Integrative Biomedicine
👉 www.mdc-berlin.de/phd 👈