Vern Dolinsky
@verndolinsky.bsky.social
Co-lead of DREAM, the #Diabetes Theme
@dream-diabetes.bsky.social at the Children's Hospital Research Institute of Manitoba
Professor of Pharmacology & Therapeutics @um-radyfhs.bsky.social @chrimanitoba.bsky.social
@dream-diabetes.bsky.social at the Children's Hospital Research Institute of Manitoba
Professor of Pharmacology & Therapeutics @um-radyfhs.bsky.social @chrimanitoba.bsky.social
Pinned
Looking forward to the 14th Annual DREAM Symposium will be on Nov 13, 2025, and the DREAM Trainee Day will be Nov 12. Free to Register Here! tinyurl.com/5d6em33b #Diabetes #Research #Symposium @chrimanitoba.bsky.social @um-radyfhs.bsky.social
Reposted by Vern Dolinsky
We’re honoured to welcome the Dr. Heather Dean Lectureship speaker Dr. Lindsay Crowshoe from @ucalgary.bsky.social to the DREAM Symposium! The presentation will be hybrid; contact dream@chrim.ca for the Zoom link. Deadline to register is Nov 10! tinyurl.com/5d6em33b @chrimanitoba.bsky.social
November 5, 2025 at 5:16 PM
We’re honoured to welcome the Dr. Heather Dean Lectureship speaker Dr. Lindsay Crowshoe from @ucalgary.bsky.social to the DREAM Symposium! The presentation will be hybrid; contact dream@chrim.ca for the Zoom link. Deadline to register is Nov 10! tinyurl.com/5d6em33b @chrimanitoba.bsky.social
Reposted by Vern Dolinsky
The 14th Annual DREAM Symposium and DREAM Trainee Day are only days away! We have a great day planned. Don't miss this! Registration closes tonight! tinyurl.com/5d6em33b contact dream@chrim.ca #Diabetes #Research #Symposium @chrimanitoba.bsky.social @um-radyfhs.bsky.social
November 11, 2025 at 4:57 AM
The 14th Annual DREAM Symposium and DREAM Trainee Day are only days away! We have a great day planned. Don't miss this! Registration closes tonight! tinyurl.com/5d6em33b contact dream@chrim.ca #Diabetes #Research #Symposium @chrimanitoba.bsky.social @um-radyfhs.bsky.social
Maternal #Obesity Programs Transgenerational Glucose Intolerance in Pregnant Female Offspring #DOHaD #diabetes @dream-diabetes.bsky.social diabetesjournals.org/diabetes/art...
Maternal Obesity Programs Glucose Intolerance in Pregnant Female Offspring
Maternal obesity is a known risk factor for metabolic dysfunction in offspring; however, its effect on metabolism during pregnancy in female offspring rema
diabetesjournals.org
November 12, 2025 at 6:47 PM
Maternal #Obesity Programs Transgenerational Glucose Intolerance in Pregnant Female Offspring #DOHaD #diabetes @dream-diabetes.bsky.social diabetesjournals.org/diabetes/art...
Systematic REVIEW: GLP-1 agonist therapy for gestational #diabetes journals.lww.com/md-journal/f...
journals.lww.com
November 10, 2025 at 4:45 PM
Systematic REVIEW: GLP-1 agonist therapy for gestational #diabetes journals.lww.com/md-journal/f...
Cellular acyl-CoA profiling reveals SLC25A42/SLC25A16 in #mitochondria import and #metabolism @natmetabolism.nature.com rdcu.be/eN5N4
Cellular pan-chain acyl-CoA profiling reveals SLC25A42/SLC25A16 in mitochondrial CoA import and metabolism
Nature Metabolism - By developing a method that allows detection of transient, low-abundance acyl-CoA species, Liu et al. provide a thorough characterization of coenzyme A dynamics and subcellular...
rdcu.be
November 3, 2025 at 6:08 PM
Cellular acyl-CoA profiling reveals SLC25A42/SLC25A16 in #mitochondria import and #metabolism @natmetabolism.nature.com rdcu.be/eN5N4
From the ECHO Cohort Study (n=13,810) Association of Maternal Pre- #pregnancy BMI With Offspring Cardiometabolic Outcomes in Childhood #DOHaD #obesity @dream-diabetes.bsky.social @dohadcanada.bsky.social onlinelibrary.wiley.com/doi/10.1002/...
Association of Maternal Prepregnancy BMI With Offspring Cardiometabolic Outcomes in Childhood
Objective This study aimed to evaluate associations of maternal prepregnancy BMI with offspring BMI and blood pressure in childhood, specifically for infants born preterm. Methods In this observat...
onlinelibrary.wiley.com
October 31, 2025 at 2:01 AM
From the ECHO Cohort Study (n=13,810) Association of Maternal Pre- #pregnancy BMI With Offspring Cardiometabolic Outcomes in Childhood #DOHaD #obesity @dream-diabetes.bsky.social @dohadcanada.bsky.social onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Vern Dolinsky
Discover MyRoad, a platform supported by CIHR, offering research training & mentorship in #obesity, #diabetes & #cardiometabolic #diseases. New opportunities this fall include cohort training, travel awards & more. 🎓✈️
Learn more: www.myroadplatform.ca/en
Contact: MyRoad.MaRoute@criucpq.ulaval.ca
Learn more: www.myroadplatform.ca/en
Contact: MyRoad.MaRoute@criucpq.ulaval.ca
September 2, 2025 at 6:46 PM
Discover MyRoad, a platform supported by CIHR, offering research training & mentorship in #obesity, #diabetes & #cardiometabolic #diseases. New opportunities this fall include cohort training, travel awards & more. 🎓✈️
Learn more: www.myroadplatform.ca/en
Contact: MyRoad.MaRoute@criucpq.ulaval.ca
Learn more: www.myroadplatform.ca/en
Contact: MyRoad.MaRoute@criucpq.ulaval.ca
Looking forward to the 14th Annual DREAM Symposium will be on Nov 13, 2025, and the DREAM Trainee Day will be Nov 12. Free to Register Here! tinyurl.com/5d6em33b #Diabetes #Research #Symposium @chrimanitoba.bsky.social @um-radyfhs.bsky.social
October 30, 2025 at 1:01 AM
Looking forward to the 14th Annual DREAM Symposium will be on Nov 13, 2025, and the DREAM Trainee Day will be Nov 12. Free to Register Here! tinyurl.com/5d6em33b #Diabetes #Research #Symposium @chrimanitoba.bsky.social @um-radyfhs.bsky.social
Reposted by Vern Dolinsky
Introducing the second keynote speaker of the DREAM #Symposium: Making Connections for Innovation, Dr. Lorraine Lipscombe from @utoronto.ca! Mark your calendars for Nov 13📅 Register here: tinyurl.com/5d6em33b @chrimanitoba.bsky.social @um-radyfhs.bsky.social @nhp-uoft.bsky.social #Diabetes #Research
October 3, 2025 at 8:24 PM
Introducing the second keynote speaker of the DREAM #Symposium: Making Connections for Innovation, Dr. Lorraine Lipscombe from @utoronto.ca! Mark your calendars for Nov 13📅 Register here: tinyurl.com/5d6em33b @chrimanitoba.bsky.social @um-radyfhs.bsky.social @nhp-uoft.bsky.social #Diabetes #Research
Reposted by Vern Dolinsky
We’re excited to announce our third keynote speaker for the 2025 DREAM #Symposium: Dr. Barry Lavallee, Chief Executive Officer of Keewatinohk Inniniw Minoayawin Inc.! Don't miss this event! Register here: tinyurl.com/5d6em33b @chrimanitoba.bsky.social @um-radyfhs.bsky.social #Diabetes #Research
October 15, 2025 at 3:37 PM
We’re excited to announce our third keynote speaker for the 2025 DREAM #Symposium: Dr. Barry Lavallee, Chief Executive Officer of Keewatinohk Inniniw Minoayawin Inc.! Don't miss this event! Register here: tinyurl.com/5d6em33b @chrimanitoba.bsky.social @um-radyfhs.bsky.social #Diabetes #Research
Reposted by Vern Dolinsky
I recently had the opportunity to chat with Dr. Shazhan Amed about how she is using data in innovative ways to improve outcomes for children and youth living with type 1 diabetes. Thanks to the T2D Network (part of IHSTS) for hosting this conversation. www.youtube.com/watch?v=Eazx...
Empowering Diabetes Care Integrating Health Information
YouTube video by T2D Network
www.youtube.com
October 20, 2025 at 9:47 PM
I recently had the opportunity to chat with Dr. Shazhan Amed about how she is using data in innovative ways to improve outcomes for children and youth living with type 1 diabetes. Thanks to the T2D Network (part of IHSTS) for hosting this conversation. www.youtube.com/watch?v=Eazx...
Functional recovery of islet β cells in human type 2 #diabetes: Transcriptome signatures unveil therapeutic approaches @dream-diabetes.bsky.social @chrisadoucette.bsky.social www.science.org/doi/10.1126/...
Functional recovery of islet β cells in human type 2 diabetes: Transcriptome signatures unveil therapeutic approaches
Human T2D beta cell function was restored, the rescuing mechanisms disentangled, and hits identified to promote T2D remission.
www.science.org
October 21, 2025 at 7:08 PM
Functional recovery of islet β cells in human type 2 #diabetes: Transcriptome signatures unveil therapeutic approaches @dream-diabetes.bsky.social @chrisadoucette.bsky.social www.science.org/doi/10.1126/...
From the HAPO study (n=112) : From Mothers With Hyperglycemia in Pregnancy 19 cord blood DNA Methylation CpG Predict Offspring beta cell dysfunction at ages 7, 11 and 18 #DOHaD @dohadcanada.bsky.social @dream-diabetes.bsky.social @adapubs.bsky.social diabetesjournals.org/diabetes/art...
August 29, 2025 at 4:58 PM
From the HAPO study (n=112) : From Mothers With Hyperglycemia in Pregnancy 19 cord blood DNA Methylation CpG Predict Offspring beta cell dysfunction at ages 7, 11 and 18 #DOHaD @dohadcanada.bsky.social @dream-diabetes.bsky.social @adapubs.bsky.social diabetesjournals.org/diabetes/art...
Reposted by Vern Dolinsky
🚨New in JAMA Pediatrics: Edmondson, Shah & Gregory discuss the promise & challenges of using GLP-1 receptor agonists for youth obesity. From safety concerns to access barriers, the piece highlights key unanswered questions for care & policy. 📖👇
jamanetwork.com/journals/jam... #obesity #youth #GLP1
jamanetwork.com/journals/jam... #obesity #youth #GLP1
Glucagon-Like Peptide-1 Receptor Agonists and Youth Obesity
This Viewpoint discusses the use of glucagon-like peptide-1 receptor agonist treatments for weight management in youth.
jamanetwork.com
August 26, 2025 at 4:38 PM
🚨New in JAMA Pediatrics: Edmondson, Shah & Gregory discuss the promise & challenges of using GLP-1 receptor agonists for youth obesity. From safety concerns to access barriers, the piece highlights key unanswered questions for care & policy. 📖👇
jamanetwork.com/journals/jam... #obesity #youth #GLP1
jamanetwork.com/journals/jam... #obesity #youth #GLP1
Transcriptomics reveals that Maternal western diet has a lasting impact of dysregulated #metabolism and RNA processing #genes in the skeletal muscles of Japanese Macaque offspring #DOHaD @dohadcanada.bsky.social @dream-diabetes.bsky.social
rdcu.be/eCbj2
rdcu.be/eCbj2
Maternal Western-style diet has a persistent effect on offspring gene expression in skeletal muscle of Japanese macaques
Scientific Reports - Maternal Western-style diet has a persistent effect on offspring gene expression in skeletal muscle of Japanese macaques
rdcu.be
August 25, 2025 at 12:32 AM
Transcriptomics reveals that Maternal western diet has a lasting impact of dysregulated #metabolism and RNA processing #genes in the skeletal muscles of Japanese Macaque offspring #DOHaD @dohadcanada.bsky.social @dream-diabetes.bsky.social
rdcu.be/eCbj2
rdcu.be/eCbj2
Metabolomic and transcriptomic remodeling of bone marrow myeloid cells in response to maternal #obesity #DOHaD @dream-diabetes.bsky.social @dohadcanada.bsky.social journals.physiology.org/doi/full/10....
August 21, 2025 at 7:15 PM
Metabolomic and transcriptomic remodeling of bone marrow myeloid cells in response to maternal #obesity #DOHaD @dream-diabetes.bsky.social @dohadcanada.bsky.social journals.physiology.org/doi/full/10....
Parental #obesity predisposes male and female offspring to exacerbated cardiac dysfunction and increased mortality after myocardial infarction #DOHaD @dohadcanada.bsky.social @dream-diabetes.bsky.social journals.physiology.org/doi/full/10....
Parental obesity predisposes male and female offspring to exacerbated cardiac dysfunction and increased mortality after myocardial infarction | American Journal of Physiology-Heart and Circulatory Phy...
Acute myocardial infarction (MI) is a leading cause of death worldwide, accounting for >1 million deaths/year in the United States alone. Although parental obesity is a risk factor for offspring cardi...
journals.physiology.org
August 12, 2025 at 6:21 PM
Parental #obesity predisposes male and female offspring to exacerbated cardiac dysfunction and increased mortality after myocardial infarction #DOHaD @dohadcanada.bsky.social @dream-diabetes.bsky.social journals.physiology.org/doi/full/10....
Wow! check this out: #Proteomic profiling from pregnant human islets donors reveals the adaptations of the human endocrine pancreas to #pregnancy @nature.com pmc.ncbi.nlm.nih.gov/articles/PMC...
August 12, 2025 at 6:14 PM
Wow! check this out: #Proteomic profiling from pregnant human islets donors reveals the adaptations of the human endocrine pancreas to #pregnancy @nature.com pmc.ncbi.nlm.nih.gov/articles/PMC...
REVIEW: Role of #mitochondrial function in the pathogenesis of #diabetes @dream-diabetes.bsky.social
frontiersin.org/journals/end...
frontiersin.org/journals/end...
August 11, 2025 at 3:45 PM
REVIEW: Role of #mitochondrial function in the pathogenesis of #diabetes @dream-diabetes.bsky.social
frontiersin.org/journals/end...
frontiersin.org/journals/end...
UCP2 inhibition eliminates pancreatic beta cell autoinflammation in type 2 #diabetes with MitoG: An #islet #mitochondria targeting nanomedicine @chrisadoucette.bsky.social @dream-diabetes.bsky.social @nature.com
rdcu.be/eAfT2
rdcu.be/eAfT2
UCP2 inhibition eliminates pancreatic β cell autoinflammation in T2DM with islet-mitochondrial sequential targeting nanomedicines
Nature Communications - The relationship between pancreatic β-cell dysfunction and autoinflammation in T2DM is unclear. Here, the authors show the key role of a UCP2/mtDNA/STING axis in the...
rdcu.be
August 11, 2025 at 3:29 PM
UCP2 inhibition eliminates pancreatic beta cell autoinflammation in type 2 #diabetes with MitoG: An #islet #mitochondria targeting nanomedicine @chrisadoucette.bsky.social @dream-diabetes.bsky.social @nature.com
rdcu.be/eAfT2
rdcu.be/eAfT2
The protein deacetylase SIRT2 exerts #metabolic control over adaptive β cell proliferation @dream-diabetes.bsky.social @jclinical-invest.bsky.social www.jci.org/articles/vie...
JCI -
Show
jci.org
August 8, 2025 at 1:14 PM
The protein deacetylase SIRT2 exerts #metabolic control over adaptive β cell proliferation @dream-diabetes.bsky.social @jclinical-invest.bsky.social www.jci.org/articles/vie...
I'm really looking forward to this presentation!
We're thrilled to introduce the first keynote speaker of the 14th Annual DREAM #Symposium: Making Connections for Innovation, Dr. Erin Mulvihill from @uottawa.ca. Mark your calendars for Nov 13! Register here: tinyurl.com/5d6em33b @chrimanitoba.bsky.social @um-radyfhs.bsky.social #Diabetes #Research
August 8, 2025 at 1:11 PM
I'm really looking forward to this presentation!
Reposted by Vern Dolinsky
🎉 Congratulations to all the researchers awarded funding through @chrimanitoba.bsky.social! Special shout out to DREAM researchers Drs. @verndolinsky.bsky.social, @thompsonisletlab.bsky.social, @chrisadoucette.bsky.social, and Lucy Marzban! 👏 Explore the funded projects: www.chrim.ca/fundedprojec...
Funded Projects – Children’s Hospital Research Institute of Manitoba
www.chrim.ca
August 5, 2025 at 7:08 PM
🎉 Congratulations to all the researchers awarded funding through @chrimanitoba.bsky.social! Special shout out to DREAM researchers Drs. @verndolinsky.bsky.social, @thompsonisletlab.bsky.social, @chrisadoucette.bsky.social, and Lucy Marzban! 👏 Explore the funded projects: www.chrim.ca/fundedprojec...
Reposted by Vern Dolinsky
Happening TODAY! Join the DREAM Trainees in 500 JBRC from 12 - 1 p.m., where Corey Sanderson (Doucette lab) and Caitlin Menzies (@verndolinsky.bsky.social lab) will share insights into their research methods. Don’t miss it! 🔬🧬 @chrimanitoba.bsky.social #diabetes #research #mice #betacell #t2d
July 29, 2025 at 3:00 PM
Happening TODAY! Join the DREAM Trainees in 500 JBRC from 12 - 1 p.m., where Corey Sanderson (Doucette lab) and Caitlin Menzies (@verndolinsky.bsky.social lab) will share insights into their research methods. Don’t miss it! 🔬🧬 @chrimanitoba.bsky.social #diabetes #research #mice #betacell #t2d
Reposted by Vern Dolinsky
DREAM team photos at the annual @chrimanitoba.bsky.social Summer Picnic ☀️🌭A perfect summer day spent with even better people! 😎
July 25, 2025 at 4:57 PM
DREAM team photos at the annual @chrimanitoba.bsky.social Summer Picnic ☀️🌭A perfect summer day spent with even better people! 😎