Vern Dolinsky
@verndolinsky.bsky.social
Co-lead of DREAM, the #Diabetes Theme
@dream-diabetes.bsky.social at the Children's Hospital Research Institute of Manitoba
Professor of Pharmacology & Therapeutics @um-radyfhs.bsky.social @chrimanitoba.bsky.social
@dream-diabetes.bsky.social at the Children's Hospital Research Institute of Manitoba
Professor of Pharmacology & Therapeutics @um-radyfhs.bsky.social @chrimanitoba.bsky.social
Pinned
BMC Journals | Open access, community-focused
BMC is a leader in open access publishing, driving progress in the life sciences, health sciences, medicine and applied sciences.
rdcu.be
🧵 1/7 From @dream-diabetes.bsky.social and the Next Generation cohort study: Differential effects of type 2 #diabetes and gestational diabetes on maternal and cord blood adipokines and newborn weight #DOHaD @dohadcanada.bsky.social rdcu.be/eQ0e2
Molecular profile of human ischemic cardiomyopathy in #diabetes reveals reduced mitochondrial complex I and elevated very long chain acylcarnitines @embomolmed.org
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Left ventricular myocardial molecular profile of human diabetic ischaemic cardiomyopathy - EMBO Molecular Medicine
Ischaemic cardiomyopathy is the most common cause of heart failure and often coexists with diabetes mellitus, which worsens patient symptom burden and outcomes. Yet, their combined effects are seldom ...
link.springer.com
January 2, 2026 at 8:34 PM
Molecular profile of human ischemic cardiomyopathy in #diabetes reveals reduced mitochondrial complex I and elevated very long chain acylcarnitines @embomolmed.org
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Drug Discovery and Development for #Heart Failure Using Multi-Omics Approaches www.mdpi.com/3228750
January 2, 2026 at 8:25 PM
Drug Discovery and Development for #Heart Failure Using Multi-Omics Approaches www.mdpi.com/3228750
Maternal #obesity damages blood-brain barrier structure and function in the progeny: the beneficial impact of cross-fostering by lean mothers @apspublications.bsky.social @dohadcanada.bsky.social #DOHaD journals.physiology.org/doi/full/10....
January 1, 2026 at 7:30 PM
Maternal #obesity damages blood-brain barrier structure and function in the progeny: the beneficial impact of cross-fostering by lean mothers @apspublications.bsky.social @dohadcanada.bsky.social #DOHaD journals.physiology.org/doi/full/10....
How does the timing of in utero exposure to maternal #diabetes shape offspring health risk? This paper from the Next Generation birth cohort (n=210) explores this question @dream-diabetes.bsky.social @meaghanjones.bsky.social #DOHaD
link.springer.com/article/10.1...
link.springer.com/article/10.1...
In-utero exposure to maternal diabetes and DNA methylation alterations in the Next Generation birth cohort - Clinical Epigenetics
Introduction The incidence of type 2 diabetes (T2D) in youth is increasing and in-utero exposure to maternal diabetes is a known risk factor, with higher risk associated with pregestational T2D exposu...
link.springer.com
December 23, 2025 at 5:02 PM
How does the timing of in utero exposure to maternal #diabetes shape offspring health risk? This paper from the Next Generation birth cohort (n=210) explores this question @dream-diabetes.bsky.social @meaghanjones.bsky.social #DOHaD
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Relationship between maternal #obesity, birth weight, and fetal adiponectin/leptin ratio: a potential early biomarker of cardiometabolic risk @apspublications.bsky.social @dream-diabetes.bsky.social journals.physiology.org/doi/full/10....
Relationship between maternal obesity, birth weight, and fetal adiponectin/leptin ratio: a potential early biomarker of cardiometabolic risk | American Journal of Physiology-Endocrinology and Metaboli...
Adiponectin and leptin are key adipokines that play crucial roles in metabolic regulation and in fetal and neonatal growth. In adults, lower adiponectin/leptin ratio (AdipoQ/Lep) has been suggested as...
journals.physiology.org
December 22, 2025 at 7:17 PM
Relationship between maternal #obesity, birth weight, and fetal adiponectin/leptin ratio: a potential early biomarker of cardiometabolic risk @apspublications.bsky.social @dream-diabetes.bsky.social journals.physiology.org/doi/full/10....
Reposted by Vern Dolinsky
Analysis of human pancreas indicates that the molecular mechanisms driving #pregnancy induced #islet adaptations in humans differ from those in mice, highlighting the need for human-based studies @natcomms.nature.com www.nature.com/articles/s41...
A new paradigm of islet adaptations in human pregnancy: insights from immunohistochemistry and proteomics - Nature Communications
Here the authors show that human pancreatic islets adapt during pregnancy with increased α-cell area and GLP-1 abundance, while key differences from islet adaptations in mouse pregnancy include unchan...
www.nature.com
July 21, 2025 at 10:37 AM
Analysis of human pancreas indicates that the molecular mechanisms driving #pregnancy induced #islet adaptations in humans differ from those in mice, highlighting the need for human-based studies @natcomms.nature.com www.nature.com/articles/s41...
🧵 1/7 From @dream-diabetes.bsky.social and the Next Generation cohort study: Differential effects of type 2 #diabetes and gestational diabetes on maternal and cord blood adipokines and newborn weight #DOHaD @dohadcanada.bsky.social rdcu.be/eQ0e2
BMC Journals | Open access, community-focused
BMC is a leader in open access publishing, driving progress in the life sciences, health sciences, medicine and applied sciences.
rdcu.be
December 20, 2025 at 10:24 PM
🧵 1/7 From @dream-diabetes.bsky.social and the Next Generation cohort study: Differential effects of type 2 #diabetes and gestational diabetes on maternal and cord blood adipokines and newborn weight #DOHaD @dohadcanada.bsky.social rdcu.be/eQ0e2
Reposted by Vern Dolinsky
On Nov 13, 2025, we hosted the 14th Annual DREAM Symposium, Making Connections for Innovation. We were honoured to recognize Frances Desjarlais and Dr. Barry Lavallee with a Blanket Ceremony led by Elder Jack.
Thank you to our sponsors, speakers, committee, and attendees—see you next year! #diabetes
Thank you to our sponsors, speakers, committee, and attendees—see you next year! #diabetes
December 19, 2025 at 7:23 PM
On Nov 13, 2025, we hosted the 14th Annual DREAM Symposium, Making Connections for Innovation. We were honoured to recognize Frances Desjarlais and Dr. Barry Lavallee with a Blanket Ceremony led by Elder Jack.
Thank you to our sponsors, speakers, committee, and attendees—see you next year! #diabetes
Thank you to our sponsors, speakers, committee, and attendees—see you next year! #diabetes
Reposted by Vern Dolinsky
Another year, another team photo of this amazing group. #DREAMtheme 📷✨ @chrimanitoba.bsky.social @um-radyfhs.bsky.social
December 19, 2025 at 7:35 PM
Another year, another team photo of this amazing group. #DREAMtheme 📷✨ @chrimanitoba.bsky.social @um-radyfhs.bsky.social
Reposted by Vern Dolinsky
Last month was the DREAM Trainee Day, centered around Research That Resonates — from asking impactful research questions to knowledge translation and inclusive leadership. Trainees ended the day by presenting their outstanding work and networked during the poster session ✨🔬💡@chrimanitoba.bsky.social
December 15, 2025 at 6:49 PM
Last month was the DREAM Trainee Day, centered around Research That Resonates — from asking impactful research questions to knowledge translation and inclusive leadership. Trainees ended the day by presenting their outstanding work and networked during the poster session ✨🔬💡@chrimanitoba.bsky.social
Reposted by Vern Dolinsky
Thanks to the T2D Network for inviting me to chat with one of my favourite people - Jon McGavock from @dream-diabetes.bsky.social - about his research in active transportation to improve health outcomes. This was such a fun and informative interview - take a look! 🧪 www.youtube.com/watch?v=sif1...
Active Transportation with Dr. Jon McGavock
YouTube video by T2D Network
www.youtube.com
November 24, 2025 at 2:32 PM
Thanks to the T2D Network for inviting me to chat with one of my favourite people - Jon McGavock from @dream-diabetes.bsky.social - about his research in active transportation to improve health outcomes. This was such a fun and informative interview - take a look! 🧪 www.youtube.com/watch?v=sif1...
Reposted by Vern Dolinsky
🧵(1/12) November is Diabetes Awareness Month, and we have many works coming out from the CIRTN labs focusing on islet biology and diabetes. For the beginning of Nov 2025, we have papers from Drs Thompson, Verchere, Chen, Dhanvantari, Hill, Hoesli, Kin, Levings, Lynn, Riddell, Rutter and Wheeler.
November 17, 2025 at 11:26 PM
🧵(1/12) November is Diabetes Awareness Month, and we have many works coming out from the CIRTN labs focusing on islet biology and diabetes. For the beginning of Nov 2025, we have papers from Drs Thompson, Verchere, Chen, Dhanvantari, Hill, Hoesli, Kin, Levings, Lynn, Riddell, Rutter and Wheeler.
Reposted by Vern Dolinsky
We had a wonderful evening celebrating with our CHRIM community recently at the Child Health Research Days awards dinner. Congratulations to all the winners!
Find a full list of all winners and more photos by visiting our link in bio to see highlights from CHRD 2025.
Find a full list of all winners and more photos by visiting our link in bio to see highlights from CHRD 2025.
November 3, 2025 at 8:26 PM
We had a wonderful evening celebrating with our CHRIM community recently at the Child Health Research Days awards dinner. Congratulations to all the winners!
Find a full list of all winners and more photos by visiting our link in bio to see highlights from CHRD 2025.
Find a full list of all winners and more photos by visiting our link in bio to see highlights from CHRD 2025.
Reposted by Vern Dolinsky
📢🎉New study from our lab on circulating SASP factors suggests a novel senescent cell biomarker across #T1D stages! Congrats🥳Camille Jasmine and @dream-diabetes.bsky.social trainees Grateful to TrialNet @chrimanitoba.bsky.social @cirtn.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Circulating senescence-associated secretory phenotype factors across the stages of type 1 diabetes in a cross-sectional cohort - Scientific Reports
Scientific Reports - Circulating senescence-associated secretory phenotype factors across the stages of type 1 diabetes in a cross-sectional cohort
www.nature.com
November 20, 2025 at 4:28 PM
📢🎉New study from our lab on circulating SASP factors suggests a novel senescent cell biomarker across #T1D stages! Congrats🥳Camille Jasmine and @dream-diabetes.bsky.social trainees Grateful to TrialNet @chrimanitoba.bsky.social @cirtn.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Vern Dolinsky
Our team is at the @dream-diabetes.bsky.social workshop in Winnipeg this week! Dr. Lorraine Lipscombe presented about the Network’s progress and our trainees Amrit Thandi and Jashnoor Chhina presented posters. Congrats to Amrit for winning best oral presentation! 🙌
November 14, 2025 at 4:44 PM
Our team is at the @dream-diabetes.bsky.social workshop in Winnipeg this week! Dr. Lorraine Lipscombe presented about the Network’s progress and our trainees Amrit Thandi and Jashnoor Chhina presented posters. Congrats to Amrit for winning best oral presentation! 🙌
Reposted by Vern Dolinsky
This past September, DREAM trainee Khushali Trivedi (PhD student, @verndolinsky.bsky.social lab) was selected to orally present her research at the Canadian Lipid & Vascular Summit in Saskatoon, SK. Way to go, Khushali! 👏
November 20, 2025 at 9:30 PM
This past September, DREAM trainee Khushali Trivedi (PhD student, @verndolinsky.bsky.social lab) was selected to orally present her research at the Canadian Lipid & Vascular Summit in Saskatoon, SK. Way to go, Khushali! 👏
Our latest REVIEW: Rethinking Childhood-Onset Hypertrophic Cardiomyopathy: A Review of Molecular Mechanisms and Unique Therapy Considerations www.mdpi.com/3512392
www.mdpi.com
November 20, 2025 at 8:34 PM
Our latest REVIEW: Rethinking Childhood-Onset Hypertrophic Cardiomyopathy: A Review of Molecular Mechanisms and Unique Therapy Considerations www.mdpi.com/3512392
Reposted by Vern Dolinsky
Today is #WorldDiabetesDay, an opportunity to raise awareness, foster dialogue, and recognizing and celebrating the role of fundamental science, clinical research, and community in supporting well-being for people living with diabetes. #WDD2025 #DiabetesAwareness #Diabetes
November 14, 2025 at 3:06 PM
Today is #WorldDiabetesDay, an opportunity to raise awareness, foster dialogue, and recognizing and celebrating the role of fundamental science, clinical research, and community in supporting well-being for people living with diabetes. #WDD2025 #DiabetesAwareness #Diabetes
Reposted by Vern Dolinsky
We’re honoured to welcome the Dr. Heather Dean Lectureship speaker Dr. Lindsay Crowshoe from @ucalgary.bsky.social to the DREAM Symposium! The presentation will be hybrid; contact dream@chrim.ca for the Zoom link. Deadline to register is Nov 10! tinyurl.com/5d6em33b @chrimanitoba.bsky.social
November 5, 2025 at 5:16 PM
We’re honoured to welcome the Dr. Heather Dean Lectureship speaker Dr. Lindsay Crowshoe from @ucalgary.bsky.social to the DREAM Symposium! The presentation will be hybrid; contact dream@chrim.ca for the Zoom link. Deadline to register is Nov 10! tinyurl.com/5d6em33b @chrimanitoba.bsky.social
Reposted by Vern Dolinsky
The 14th Annual DREAM Symposium and DREAM Trainee Day are only days away! We have a great day planned. Don't miss this! Registration closes tonight! tinyurl.com/5d6em33b contact dream@chrim.ca #Diabetes #Research #Symposium @chrimanitoba.bsky.social @um-radyfhs.bsky.social
November 11, 2025 at 4:57 AM
The 14th Annual DREAM Symposium and DREAM Trainee Day are only days away! We have a great day planned. Don't miss this! Registration closes tonight! tinyurl.com/5d6em33b contact dream@chrim.ca #Diabetes #Research #Symposium @chrimanitoba.bsky.social @um-radyfhs.bsky.social
Maternal #Obesity Programs Transgenerational Glucose Intolerance in Pregnant Female Offspring #DOHaD #diabetes @dream-diabetes.bsky.social diabetesjournals.org/diabetes/art...
Maternal Obesity Programs Glucose Intolerance in Pregnant Female Offspring
Maternal obesity is a known risk factor for metabolic dysfunction in offspring; however, its effect on metabolism during pregnancy in female offspring rema
diabetesjournals.org
November 12, 2025 at 6:47 PM
Maternal #Obesity Programs Transgenerational Glucose Intolerance in Pregnant Female Offspring #DOHaD #diabetes @dream-diabetes.bsky.social diabetesjournals.org/diabetes/art...
Systematic REVIEW: GLP-1 agonist therapy for gestational #diabetes journals.lww.com/md-journal/f...
journals.lww.com
November 10, 2025 at 4:45 PM
Systematic REVIEW: GLP-1 agonist therapy for gestational #diabetes journals.lww.com/md-journal/f...
Cellular acyl-CoA profiling reveals SLC25A42/SLC25A16 in #mitochondria import and #metabolism @natmetabolism.nature.com rdcu.be/eN5N4
Cellular pan-chain acyl-CoA profiling reveals SLC25A42/SLC25A16 in mitochondrial CoA import and metabolism
Nature Metabolism - By developing a method that allows detection of transient, low-abundance acyl-CoA species, Liu et al. provide a thorough characterization of coenzyme A dynamics and subcellular...
rdcu.be
November 3, 2025 at 6:08 PM
Cellular acyl-CoA profiling reveals SLC25A42/SLC25A16 in #mitochondria import and #metabolism @natmetabolism.nature.com rdcu.be/eN5N4
From the ECHO Cohort Study (n=13,810) Association of Maternal Pre- #pregnancy BMI With Offspring Cardiometabolic Outcomes in Childhood #DOHaD #obesity @dream-diabetes.bsky.social @dohadcanada.bsky.social onlinelibrary.wiley.com/doi/10.1002/...
Association of Maternal Prepregnancy BMI With Offspring Cardiometabolic Outcomes in Childhood
Objective This study aimed to evaluate associations of maternal prepregnancy BMI with offspring BMI and blood pressure in childhood, specifically for infants born preterm. Methods In this observat...
onlinelibrary.wiley.com
October 31, 2025 at 2:01 AM
From the ECHO Cohort Study (n=13,810) Association of Maternal Pre- #pregnancy BMI With Offspring Cardiometabolic Outcomes in Childhood #DOHaD #obesity @dream-diabetes.bsky.social @dohadcanada.bsky.social onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Vern Dolinsky
Discover MyRoad, a platform supported by CIHR, offering research training & mentorship in #obesity, #diabetes & #cardiometabolic #diseases. New opportunities this fall include cohort training, travel awards & more. 🎓✈️
Learn more: www.myroadplatform.ca/en
Contact: MyRoad.MaRoute@criucpq.ulaval.ca
Learn more: www.myroadplatform.ca/en
Contact: MyRoad.MaRoute@criucpq.ulaval.ca
September 2, 2025 at 6:46 PM
Discover MyRoad, a platform supported by CIHR, offering research training & mentorship in #obesity, #diabetes & #cardiometabolic #diseases. New opportunities this fall include cohort training, travel awards & more. 🎓✈️
Learn more: www.myroadplatform.ca/en
Contact: MyRoad.MaRoute@criucpq.ulaval.ca
Learn more: www.myroadplatform.ca/en
Contact: MyRoad.MaRoute@criucpq.ulaval.ca