TLDR and take-home key points:

✅ PTZ 3.375g IV Q6H is effective for MIC ≤8 mg/L

✅ Neither standard nor high-dose achieves 90% PTA for MIC ≥16 mg/L w/ short infusions

✅ Extended infusions are key for high-MIC infections!

#medsky #pharmsky #EMsky #IDsky #MedEd #AMSky #emimcc

Thanks for this interesting paper. Note that this is a small study using a surrogate outcome, personally I wouldn't immediately conclude that it actually works for stone prevention, don't you think?

#MedSky

Great, thank you for sharing this!