4. Regions with higher energy demand are involved in complex cognition, like inhibitory and memory processing, or reading.

3. Higher energy demand is associated with slow, chemical signaling of neuromodulators, such as serotonin or dopamine (transcriptomics and molecular imaging data).

2. Up to 67% higher energetic costs in evolutionarily most expanded brain regions.

Brain Imaging Setup: We measured the glucose metabolism throughout the functional connectome of the human brain (replication in three datasets using simultaneous PET/MR imaging).

1. Energy demand linearly scales with the degree of functional connectivity in individual brains.

‚Science Advances‘ published our paper in which we asked:

"Where does all the sugar go in the brain?"
doi.org/10.1126/scia...

Short answer and 4 main findings in 🧵 below.
#funding: ERC_Research
#neuroskyence