This SF clinical experience explores the use of linezolid for rifampin-susceptible #tuberculosis (RS-TB) — a drug typically reserved for resistant disease — in a diverse urban patient population. lnkd.in/eQaRpf5f

🚨 Satellite session at #UnionConf2025!
“Transforming TB detection with tongue swab-based molecular testing”
🗓️ Nov 19 | 8–9AM | Copenhagen

Beyond sputum: tongue swabs + near-POC molecular tools.

unionconf2025.abstractserver.com/programme/#/...

#TB #GlobalHealth #Diagnostics

Can a smartphone-recorded cough help detect #TB? The CODA TB DREAM Challenge shows promise: AI + clinical data reached 73.8% specificity at 80% sensitivity across 7 countries. Read more: academic.oup.com/ofid/advance...

New Lancet study in Philippines, Vietnam, South Africa, Uganda & India:

People tested for #TB prioritize diagnostics that are
• Low-cost
• Accurate
• Deliver results in 15 minutes

Findings show need to align WHO TPPs with patient preferences.
www.thelancet.com/journals/lan...

Join us for Innovating Against #TB – Community Solutions to TB Challenges

📅 Thurs, Sept 11, 2025
🕐 1–2 PM PT | 4 PM ET
✅ Up to 1 CE hour

Hear from leaders & advocates on TB programs driving change via education, advocacy & services.

🔗 Register: us02web.zoom.us/meeting/regi...

#Tuberculosis

Results from the endTB-Q trial (MSF, PIH, IRD, UCSF CTB): BDLC (bedaquiline, delamanid, linezolid, clofazimine) was not non-inferior to standard regimens for pre-XDR #TB. Longer/stronger treatments may be needed.
www.sciencedirect.com/science/arti...

We need new biomarkers to improve TB diagnosis in children. In the COMBO study, we performed a comprehensive plasma proteomic analysis across 4 countries and found several protein signatures that met the WHO target accuracy for a TB screening test: www.nature.com/articles/s41...

#tbsky #idsky

Can digital adherence tools improve #TB care at scale? We evaluated 99DOTS in Uganda during national scale-up. High uptake (87%), no harm to outcomes, but equity in access remains key. Read more: www.medrxiv.org/content/10.1... #tuberculosis

In our study of 2,904 adults with #TB symptoms across five high TB-burden countries, CRP-based screening had 84% sensitivity and 61% specificity. Though CRP didn’t meet minimum diagnostic targets overall, its accuracy varied by setting and subgroup. www.atsjournals.org/doi/10.1164/...

WHO announces landmark changes in treatment of drug-resistant #tuberculosis createsend.com/t/d-0CC16B59...

Dr. Ann M Loeffler will be presenting on advances and local strategies in pediatric #TB at the UCSF Department of Pediatrics Grand Rounds this Thursday, April 17th, from 12-1pm. Attend in person at Oberndorf Auditorium or via Zoom: bit.ly/3Go7Np2

Our study compared Uganda’s #TB treatment decision algorithm for children with the WHO's. We found these TDAs can help diagnose more TB cases, but could also lead to overtreatment. Better tests are needed to confirm TB in children. dx.plos.org/10.1371/jour...
#Tuberculosis #ChildHealth #Uganda #WHO

Despite being preventable, #TB affects thousands in the US. A major barrier to TB elimination is the lack of Medicare coverage for TB infection screening and testing. Our team describes how this policy gap affects US TB elimination efforts. rdcu.be/efcBa #TBPrevention #Medicare #CTB

Learn about how faculty at the UCSF Center for Tuberculosis are waging the fight against #TB www.ucsf.edu/news/2025/03...