Tung Le
@tunglejic.bsky.social
Dad of two, Professor, Lister Research Fellow and Wellcome Investigator at the John Innes Centre. Interested in bacterial chromosome organization & segregation, plasmids, and phages.
www.tunglelab.org
www.tunglelab.org
The first CTP switch? ParB, a bacterial DNA segregation protein.
ParB uses CTP to clamp around DNA, recruit ParA (an ATPase), and ensure chromosomes are properly inherited by daughter cells. CTP hydrolysis then recycles ParB. This represents a new regulatory principle!
ParB uses CTP to clamp around DNA, recruit ParA (an ATPase), and ensure chromosomes are properly inherited by daughter cells. CTP hydrolysis then recycles ParB. This represents a new regulatory principle!
October 11, 2025 at 11:36 AM
The first CTP switch? ParB, a bacterial DNA segregation protein.
ParB uses CTP to clamp around DNA, recruit ParA (an ATPase), and ensure chromosomes are properly inherited by daughter cells. CTP hydrolysis then recycles ParB. This represents a new regulatory principle!
ParB uses CTP to clamp around DNA, recruit ParA (an ATPase), and ensure chromosomes are properly inherited by daughter cells. CTP hydrolysis then recycles ParB. This represents a new regulatory principle!