Takahiro Osada
tosada.bsky.social
Takahiro Osada
@tosada.bsky.social
Neuroscientist. Associate Professor at Juntendo University, Tokyo, Japan

https://researchmap.jp/takosada
Reposted by Takahiro Osada
A brain injury was reported in a trial using ultrasound, framed as low-intensity TUS. Kim Butts Pauly and I reviewed the case and disagreed with how it's presented. Key acoustic data are missing.
Case: doi.org/10.1016/j.br...
Letters: www.elsa-fouragnan.com/blog | web.stanford.edu/~kimbutts/Le...
Brain Injury During Focused Ultrasound Neuromodulation for Substance Use Disorder
www.sciencedirect.com
November 3, 2025 at 11:39 AM
Reposted by Takahiro Osada
Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications!
doi.org/10.1038/s414...
September 30, 2025 at 7:39 PM
Reposted by Takahiro Osada
I still get chills

Meet Mike
*30+ years severe depression
*first hospitalized @ 13y
*20 meds
*3 rounds of ECT
*2 near-fatal suicide attempts

Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE

see videos, read paper, follow thread
doi.org/10.31234/osf...
August 10, 2025 at 6:23 PM
Reposted by Takahiro Osada
Integrating and interpreting brain maps | doi.org/10.1016/j.ti...

Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
August 4, 2025 at 2:27 PM
Reposted by Takahiro Osada
1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social

AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements...

doi.org/10.1038/s415...
July 17, 2025 at 1:36 AM
Reposted by Takahiro Osada
We have argued that the brain’s Action Mode Network controls functions required for goal-directed behavior. www.nature.com/articles/s41...

Now, in new work, we show that AMN contains distinct subnetworks for making decisions, implementing actions, and processing feedback. doi.org/10.1073/pnas...
July 10, 2025 at 7:52 PM
Reposted by Takahiro Osada
Check out this stellar work from the one-and-only @valeriejsydnor.bsky.social w/ team at @pennlinc.bsky.social + (many!) friends -- providing new evidence that thalamo-cortical connectivity coordinates the hierarchical progression of cortical plasticity in development. Out in @natneuro.nature.com.
How does the human brain coordinate hierarchical cortical development? Our work in Nature Neuroscience identifies a role for thalamocortical structural connectivity in the expression of hierarchical periods of cortical plasticity & environmental receptivity in youth 🧵 www.nature.com/articles/s41...
July 8, 2025 at 11:30 AM
Reposted by Takahiro Osada
Benchmarking methods for mapping functional connectivity in the brain | doi.org/10.1038/s415...

What is the best measure of functional connectivity (FC)?

led by @zhenqi.bsky.social in @natmethods.nature.com ⤵️
June 20, 2025 at 7:57 PM
Reposted by Takahiro Osada
It's shocking how little is known about the brainstem red nucleus. In our new paper “The human brainstem’s red nucleus was upgraded to support goal-directed action” out now in @naturecomms.bsky.social we show that current thinking on the red nucleus is in need of a serious upgrade. rdcu.be/ehbOy
April 10, 2025 at 3:46 PM
Reposted by Takahiro Osada
It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠
A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications
Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.
www.nature.com
March 26, 2025 at 1:54 AM
Reposted by Takahiro Osada
The ITRUSST Practical Guide on Transcranial Ultrasonic Stimulation (TUS) for neuromodulation is finally out, endorsed by the International Federation of Clinical Neurophysiology (IFCN). This is quite the “opus magnum” with 23 beautiful educational figures.
https://www.sciencedirect.com/science/arti…
buff.ly
January 31, 2025 at 8:14 PM
Reposted by Takahiro Osada
[Transcranial ultrasonic stimulation: IFCN-endorsed gulidelines] Murphy et al.: "Transcranial ultrasonic stimulation (TUS) is a novel technique for the non-invasive neuromodulation of superficial and deep brain regions with high spatial precision.
Open access: doi.org/10.1016/j.cl...
January 30, 2025 at 1:09 PM
Reposted by Takahiro Osada
🧠 Join our upcoming free webinar: Transcranial Ultrasound Stimulation: A Cutting-Edge Approach To Neural Circuit Exploration

🗓 On January 28th, Dr Takahiro Osada will discuss the mechanisms underlying TUS, its safety considerations and applications.

Register now for free:
meet.zoho.com/7bFafsK7P5
January 16, 2025 at 4:33 PM