Topher Hübel
@topherhuebel.bsky.social
MD PhD. DRK Kliniken Berlin & Århus Uni trained Charité & King‘s IoPPN & Karolinska & Uni Mainz. Eating. Behaviour. Genetics. Psychiatry. Analysis
Reposted by Topher Hübel
5/ One of the key findings is that prematurity and diagnostic genetic variants act additively and independently to influence phenotypic severity in developmental disorders. Premature probands have more affected organ systems and delayed developmental milestone attainment compared to term probands.
March 24, 2025 at 8:59 AM
5/ One of the key findings is that prematurity and diagnostic genetic variants act additively and independently to influence phenotypic severity in developmental disorders. Premature probands have more affected organ systems and delayed developmental milestone attainment compared to term probands.
Reposted by Topher Hübel
9/ The presence of a diagnostic genetic variant modifies the relationship between polygenic predisposition to education-related traits and gestational duration, suggesting that the nature of the diagnostic variant has the largest impact on risk of preterm delivery.
March 24, 2025 at 9:01 AM
9/ The presence of a diagnostic genetic variant modifies the relationship between polygenic predisposition to education-related traits and gestational duration, suggesting that the nature of the diagnostic variant has the largest impact on risk of preterm delivery.
lol, why would anyone do this?
October 25, 2025 at 7:22 PM
lol, why would anyone do this?
Reposted by Topher Hübel
They are formed in the early phase of acute infections. The exhausted precursors are at first found frequently, they decline without being completely lost in infections that the immune system resolves. This is the physiological response.
www.nature.com/artic...
7/8
www.nature.com/artic...
7/8
Precursors of exhausted T cells are pre-emptively formed in acute infection
Nature - T cell exhaustion was thought to be strictly associated only with chronic infections and tumours, but it turns out that acute infections also generate a subset of precursor T cells with...
www.nature.com
October 20, 2025 at 8:50 PM
They are formed in the early phase of acute infections. The exhausted precursors are at first found frequently, they decline without being completely lost in infections that the immune system resolves. This is the physiological response.
www.nature.com/artic...
7/8
www.nature.com/artic...
7/8