Tom Hale
@tom-hale.bsky.social
PhD student in the Allegretti group at MRC-LMB (cryo-EM/ET, nuclear-cytoskeletal coupling)
Reposted by Tom Hale
Ever wondered how the chemotherapeutic drug paclitaxel can target slow-dividing tumours? Check out our preprint Hale et al! @tom-hale.bsky.social found a novel non-mitotic mechanism of action for paclitaxel involving nuclear-cytoskeletal coupling via the LINC complex!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
January 20, 2025 at 2:47 PM
Ever wondered how the chemotherapeutic drug paclitaxel can target slow-dividing tumours? Check out our preprint Hale et al! @tom-hale.bsky.social found a novel non-mitotic mechanism of action for paclitaxel involving nuclear-cytoskeletal coupling via the LINC complex!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...