Tyler Weaver
tmweaver.bsky.social
Tyler Weaver
@tmweaver.bsky.social
Assistant Professor, Biochemistry and Molecular Genetics, UVA School of Medicine. Studying mechanisms of chromatin-based DNA repair.
The final piece of my postdoctoral work in the @freudlab.bsky.social was recently published!

Quite amazing what this small little repair polymerase can do to fill 1-nt gaps in chromatin.

www.nature.com/articles/s41...
March 24, 2025 at 12:33 PM
The Weaver Lab is officially open today…Let’s see if we can fill up this empty lab space!
January 2, 2025 at 5:55 PM
Our preprint from earlier this year on the oxidation-induced mutational landscape in human cells was just published! www.nature.com/articles/s41...

I’m still amazed how much chromatin structure impacts oxidation-induced mutagenesis. Our cryo-EM contribution in this work provides a glimpse into why!
December 23, 2024 at 10:58 PM
Time to introduce myself! Incoming Assistant Professor at UVA-SOM. Interested in chromatin structure and DNA repair.

Here is some of my final work in the @freudlab.bsky.social, where we determine how 1-nt gaps in the nucleosome are filled during DNA repair.

www.biorxiv.org/content/10.1...
November 15, 2024 at 2:19 PM