One study of about 100 patients Let's hope TRANSFORM provides the answer but, in the meantime I don't think you and are going to agree so let's call a halt. Good luck.

And you think that amounts to an implementation screening modality?

I agree with you. Screening black men and those with relatives with prostate cancer should be available, probably from 45.

Until we have a reliable method of determining which men have dangerous tumours and which don't, any mass (as opposed to targeted) screening programme will lead to men having treatment they don't need.

John should demand a blood test. In the unlikely event that it is declined he should make a formal complaint and pay for a test.

TRANSFORM does not have answers yet but positive PSA test then MRI and only then biopsy is becoming standard practice.

The trial has only just stated Brian

In your position I would have opted for treatment but I still say that, at this point, we are not in a position to launch a national screening programme. 3/

I know two men with high Gleeson scores and extracapsular disease 20 years ago. Both had primary treatment that failed to cure them. Both are still alive and without adverse effects in their lives, having been managed with hormone therapies for two decades. 2/

I am not suggesting that treatment was not the right decision but Gleeson scoring is not a very reliable predictor of the aggressiveness of prostate tumours.1/

Prostate Cancer UK has just begun to recruit participants for Transform, a huge long term research programme that seems to have a decent chance of leading to a reliable screening programme.

TRANSFORM trial | Prostate Cancer UK share.google/TK1WPrzABxUs...

With respect, you can't know that your life was saved. You know that you are alive but not that you would have died. Many men have prostate cancer that would never kill them. There is no reliable way of knowing which ones they are. This is the obstacle to a national screening programme.

It seems probable that Mr Mamdani despises and detests the White House rapist but one can see why he would pretend to like him.

What a world in which we now live, where the largest public companies budget for revue defied from criminal conduct.

So, you are not actually interested in the data, the facts. OK but goodbye

So let's have your data that demonstrates that NZ's Covid experience was no better than the UK's.

Hint: you won't find any.

New Zealand’s excess mortality was very low, around < 1-2% above expected deaths.

The UK’s excess deaths were much higher, at ~7.2% above expected just for one year, and multi‐year totals far greater.

I suggest you read the report or you are going to look silly.

Oh dear, we haven't found a Bozo apologist have we? I bet you don't tell you friends. Noted that you are anonymous here!