Hung Nguyen
@tienhungf91.bsky.social
Assistant Prof @UBChemistry | Computational modeling of RNA structure and folding, intrinsically disordered proteins and phase separation | BioSimLabUB.github.io
Pinned
Hung Nguyen
@tienhungf91.bsky.social
· Aug 8
RNA Structural Complexity Dictates Its Ion Atmosphere
Electrostatic interactions mediated by surrounding ions critically influence RNA behavior, yet flexible RNAs remain underexplored. We performed molecular dynamics simulations to examine three RNAs acr...
pubs.acs.org
Ecstatic to have our lab's first paper published on JPCL @pubs.acs.org. We showed the ion atmospheres of unstructured RNAs extend farther into solution compared to folded structures. pubs.acs.org/doi/10.1021/...
My lab is looking for 1-2 PhD students for Fall 2026 to develop coarse-grained and statistical mechanical models to study RNA folding, ion–RNA interactions, and biomolecular phase separation. Join us for a virtual session, register here buffalo.zoom.us/meeting/regi... @ubuffalo.bsky.social
October 21, 2025 at 3:04 PM
My lab is looking for 1-2 PhD students for Fall 2026 to develop coarse-grained and statistical mechanical models to study RNA folding, ion–RNA interactions, and biomolecular phase separation. Join us for a virtual session, register here buffalo.zoom.us/meeting/regi... @ubuffalo.bsky.social
Excited to have this work published. With @trceklab.bsky.social we show that RNA structure impedes intermolecular base pairing in germ granule.
New paper from the Trcek lab, with Siran Tian as the lead author - congratulations Siran!: www.nature.com/articles/s41...
Controlling intermolecular base pairing in Drosophila germ granules by mRNA folding and its implications in fly development - Nature Communications
Tian et al. show that RNA folding limits extensive base pairing among mRNAs in Drosophila germ granules. Instead, mRNAs interact via scattered bases exposed on the surface of folded RNAs, which may pr...
www.nature.com
September 1, 2025 at 5:14 PM
Excited to have this work published. With @trceklab.bsky.social we show that RNA structure impedes intermolecular base pairing in germ granule.
Ecstatic to have our lab's first paper published on JPCL @pubs.acs.org. We showed the ion atmospheres of unstructured RNAs extend farther into solution compared to folded structures. pubs.acs.org/doi/10.1021/...
RNA Structural Complexity Dictates Its Ion Atmosphere
Electrostatic interactions mediated by surrounding ions critically influence RNA behavior, yet flexible RNAs remain underexplored. We performed molecular dynamics simulations to examine three RNAs acr...
pubs.acs.org
August 8, 2025 at 1:37 PM
Ecstatic to have our lab's first paper published on JPCL @pubs.acs.org. We showed the ion atmospheres of unstructured RNAs extend farther into solution compared to folded structures. pubs.acs.org/doi/10.1021/...
Reposted by Hung Nguyen
🚨 We’re looking for a curious mind to join our lab at the NIH!
Passionate about #RNA biology, #MachineLearning, and the #genomics of #aging?
Interested in a postdoc or a PhD research visit at NIH? Let’s connect.
📩 DM or email for details!
#Bioinformatics #AI #ComputationalBiology
Passionate about #RNA biology, #MachineLearning, and the #genomics of #aging?
Interested in a postdoc or a PhD research visit at NIH? Let’s connect.
📩 DM or email for details!
#Bioinformatics #AI #ComputationalBiology
June 4, 2025 at 5:30 PM
🚨 We’re looking for a curious mind to join our lab at the NIH!
Passionate about #RNA biology, #MachineLearning, and the #genomics of #aging?
Interested in a postdoc or a PhD research visit at NIH? Let’s connect.
📩 DM or email for details!
#Bioinformatics #AI #ComputationalBiology
Passionate about #RNA biology, #MachineLearning, and the #genomics of #aging?
Interested in a postdoc or a PhD research visit at NIH? Let’s connect.
📩 DM or email for details!
#Bioinformatics #AI #ComputationalBiology
Reposted by Hung Nguyen
Are you looking for a faculty job? We are hiring in my department at Roswell Park NOW. Contact me for details as I await the formal ad. (Please RT.)
June 4, 2025 at 6:34 PM
Are you looking for a faculty job? We are hiring in my department at Roswell Park NOW. Contact me for details as I await the formal ad. (Please RT.)
Excited to share our lab's preprint! We found that flexible RNAs have much broadened ion atmospheres than structured RNAs. This leads us to speculate the implications on molecular recognition and phase behavior. Please check full text for other interesting details www.biorxiv.org/content/10.1...
RNA structural complexity dictates its ion atmosphere
Electrostatic interactions mediated by the surrounding ions govern virtually every facet of RNA behavior. Most studies have focused on rigid, well-folded motifs, leaving the structurally heteregeneous...
www.biorxiv.org
May 28, 2025 at 6:42 PM
Excited to share our lab's preprint! We found that flexible RNAs have much broadened ion atmospheres than structured RNAs. This leads us to speculate the implications on molecular recognition and phase behavior. Please check full text for other interesting details www.biorxiv.org/content/10.1...
Reposted by Hung Nguyen
ACTION ITEM-----ACTION ITEM
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
the word alert is in a purple circle
ALT: the word alert is in a purple circle
media.tenor.com
April 23, 2025 at 6:03 PM
ACTION ITEM-----ACTION ITEM
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Implementation of Schedule F
This is what a lot of us have been worried about.
This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs.
BUT THERE IS A COMMENT PERIOD...
1/n
Reposted by Hung Nguyen
More from the Washington Post (and this one is a doozy) regarding the President's Budget. Note that this is an aspirational document and Congress has to act (or ignore it).
[Gift Link]
wapo.st/42gLz0Z
1/n
[Gift Link]
wapo.st/42gLz0Z
1/n
Internal budget document reveals extent of Trump’s proposed health cuts
HHS would be asked to absorb a $40 billion cut, about one-third of its discretionary budget.
wapo.st
April 16, 2025 at 8:50 PM
More from the Washington Post (and this one is a doozy) regarding the President's Budget. Note that this is an aspirational document and Congress has to act (or ignore it).
[Gift Link]
wapo.st/42gLz0Z
1/n
[Gift Link]
wapo.st/42gLz0Z
1/n
Reposted by Hung Nguyen
We’re looking for fellow nerds to help us make disordered proteins druggable. Love #IDPs, #MD, #NMR, #AI, #DrugDiscovery, or #MassSpec? Let’s talk.
@bindresearch.org is hiring across the board: bindresearch.org/careers/
#compchem #compbio #NMRChat #TeamMassSpec #chemjobs @chemjobber.bsky.social
@bindresearch.org is hiring across the board: bindresearch.org/careers/
#compchem #compbio #NMRChat #TeamMassSpec #chemjobs @chemjobber.bsky.social
Careers
Careers
bindresearch.org
March 24, 2025 at 10:51 AM
We’re looking for fellow nerds to help us make disordered proteins druggable. Love #IDPs, #MD, #NMR, #AI, #DrugDiscovery, or #MassSpec? Let’s talk.
@bindresearch.org is hiring across the board: bindresearch.org/careers/
#compchem #compbio #NMRChat #TeamMassSpec #chemjobs @chemjobber.bsky.social
@bindresearch.org is hiring across the board: bindresearch.org/careers/
#compchem #compbio #NMRChat #TeamMassSpec #chemjobs @chemjobber.bsky.social
Reposted by Hung Nguyen
Text might be tiny, but here's the existing 27 vs. the proposed 15 institutes that will be left standing.
You'll probably see a number of resignations, re-assignments, and the whole thing will be administered by political appointees who will oversee funding & policy.
You'll probably see a number of resignations, re-assignments, and the whole thing will be administered by political appointees who will oversee funding & policy.
March 18, 2025 at 12:53 PM
Text might be tiny, but here's the existing 27 vs. the proposed 15 institutes that will be left standing.
You'll probably see a number of resignations, re-assignments, and the whole thing will be administered by political appointees who will oversee funding & policy.
You'll probably see a number of resignations, re-assignments, and the whole thing will be administered by political appointees who will oversee funding & policy.
Reposted by Hung Nguyen
Confirmation!!
And including open sessions!
And including open sessions!
March 17, 2025 at 5:24 PM
Confirmation!!
And including open sessions!
And including open sessions!