Calvin Tiengwe
@tiengwe-tryplab.bsky.social
parasitologist studying how pathogens survive iron starvation. Tracking antimicrobial resistance spread in West Africa. One Health advocate working at the intersection of human & animal health. #Scientist, #dad & global health advocate. 🦠🧬🔬🐄🌍
Pinned
A high-throughput protein tagging toolkit that retains endogenous untranslated regions for studying gene regulation in kinetoplastids | Open Biology
Kinetoplastid parasites cause diseases that threaten human and animal health. To survive
transitions between vertebrate hosts and insect vectors, these parasites rely on precise
regulation of gene exp...
royalsocietypublishing.org
Here it is... an amazing team effort from 3 Masters students and collaborators! Thanks to reviewers for constructive comments. Plasmids available here: www.addgene.org/search/catal...
royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org/doi/10.1098/...
Here it is... an amazing team effort from 3 Masters students and collaborators! Thanks to reviewers for constructive comments. Plasmids available here: www.addgene.org/search/catal...
royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org/doi/10.1098/...
A high-throughput protein tagging toolkit that retains endogenous untranslated regions for studying gene regulation in kinetoplastids | Open Biology
Kinetoplastid parasites cause diseases that threaten human and animal health. To survive
transitions between vertebrate hosts and insect vectors, these parasites rely on precise
regulation of gene exp...
royalsocietypublishing.org
February 26, 2025 at 7:28 AM
Here it is... an amazing team effort from 3 Masters students and collaborators! Thanks to reviewers for constructive comments. Plasmids available here: www.addgene.org/search/catal...
royalsocietypublishing.org/doi/10.1098/...
royalsocietypublishing.org/doi/10.1098/...
Reposted by Calvin Tiengwe
"Enter BioEmu-1—a deep learning model that can generate thousands of protein structures per hour on a single graphics processing unit. Today, we are making BioEmu-1 open-source"
#science #ai #microsoft
www.microsoft.com/en-us/resear...
#science #ai #microsoft
www.microsoft.com/en-us/resear...
AI is accelerating protein discovery
Meet BioEmu-1 from Microsoft Research. This deep learning model can generate thousands of protein structures per hour, unlocking new possibilities for protein scientists and drug discovery and researc...
www.microsoft.com
February 20, 2025 at 11:12 PM
"Enter BioEmu-1—a deep learning model that can generate thousands of protein structures per hour on a single graphics processing unit. Today, we are making BioEmu-1 open-source"
#science #ai #microsoft
www.microsoft.com/en-us/resear...
#science #ai #microsoft
www.microsoft.com/en-us/resear...
Reposted by Calvin Tiengwe
🧬🧪Protein codes promote selective subcellular compartmentalization | Science www.science.org/doi/10.1126/...
Henry Kilgore @itamarchinn.bsky.social @pgmikhael.bsky.social Ilan Mitnikov, et al. @aihealthmit.bsky.social @whiteheadinstitute.bsky.social @mitofficial.bsky.social
Henry Kilgore @itamarchinn.bsky.social @pgmikhael.bsky.social Ilan Mitnikov, et al. @aihealthmit.bsky.social @whiteheadinstitute.bsky.social @mitofficial.bsky.social
Protein codes promote selective subcellular compartmentalization
Cells have evolved mechanisms to distribute ~10 billion protein molecules to subcellular compartments where diverse proteins involved in shared functions must assemble. Here, we demonstrate that prote...
www.science.org
February 8, 2025 at 11:39 PM
🧬🧪Protein codes promote selective subcellular compartmentalization | Science www.science.org/doi/10.1126/...
Henry Kilgore @itamarchinn.bsky.social @pgmikhael.bsky.social Ilan Mitnikov, et al. @aihealthmit.bsky.social @whiteheadinstitute.bsky.social @mitofficial.bsky.social
Henry Kilgore @itamarchinn.bsky.social @pgmikhael.bsky.social Ilan Mitnikov, et al. @aihealthmit.bsky.social @whiteheadinstitute.bsky.social @mitofficial.bsky.social
Reposted by Calvin Tiengwe
If you're a non-UK scientist who wants to come to the UK for a postdoc, this year's Newton Fellowships are now open. You'll need a lab to host you (which could be me, but truly, could be any PI, so get in touch with someone you'd like to work with!)
royalsociety.org/grants/newto...
royalsociety.org/grants/newto...
Newton International Fellowships | Royal Society
This fellowship is for non-UK scientists who are at an early stage of their research career and wish to conduct research in the UK.
royalsociety.org
January 29, 2025 at 5:27 PM
If you're a non-UK scientist who wants to come to the UK for a postdoc, this year's Newton Fellowships are now open. You'll need a lab to host you (which could be me, but truly, could be any PI, so get in touch with someone you'd like to work with!)
royalsociety.org/grants/newto...
royalsociety.org/grants/newto...
Reposted by Calvin Tiengwe
Are you interested in #trypanosomes #biomolecularcondensates and/or #geneexpression? We are looking for a highly motivated postdoc to work with with us in the beautiful city of York!
Please share!
jobs.york.ac.uk/vacancy/post...
Please share!
jobs.york.ac.uk/vacancy/post...
January 16, 2025 at 7:54 AM
Are you interested in #trypanosomes #biomolecularcondensates and/or #geneexpression? We are looking for a highly motivated postdoc to work with with us in the beautiful city of York!
Please share!
jobs.york.ac.uk/vacancy/post...
Please share!
jobs.york.ac.uk/vacancy/post...
Excited to share our gene tagging toolkit! It's a protein tagging system that maintains regulatory elements. Originally built for Kinetoplastids but adaptable to any system - no parasite-specific sequences in vectors. Prefect for studying post-transcriptional control! www.biorxiv.org/content/10.1...
A high-throughput protein tagging toolkit that retains endogenous UTRs for studying gene regulation in Kinetoplastids
Kinetoplastid parasites cause diseases that threaten human and animal health. To survive transitions between vertebrate hosts and insect vectors, these parasites rely on precise regulation of gene exp...
www.biorxiv.org
November 23, 2024 at 10:47 PM
Excited to share our gene tagging toolkit! It's a protein tagging system that maintains regulatory elements. Originally built for Kinetoplastids but adaptable to any system - no parasite-specific sequences in vectors. Prefect for studying post-transcriptional control! www.biorxiv.org/content/10.1...