Joana Silva
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thejoanasilva.bsky.social
Joana Silva
@thejoanasilva.bsky.social
Assistant Professor & Group Leader at the UMC-CMM 🇳🇱 silva-lab.org
Science and music lover.
She/Her
Reposted by Joana Silva
First paper of our lab today @natureportfolio.bsky.social by Nussi!

We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!

@embl.org #RNAbiology #RNASky

t.co/a24Xxcxdo0
December 4, 2024 at 8:53 PM
Another cool story from @bekkerjensenlab.bsky.social and @annaconstancevind.bsky.social that sheds light on the hidden mechanisms of sunburn.

Turns out UV light doesn’t just damage DNA. It also activates the ribotoxic stress response in skin cells, driving inflammation, cell death and repair!👇
Time for our first post here 🥳 Our latest paper is online 🙌
We show that UV activates the ribotoxic stress response, which causes inflammation, cell death and thickening in skin. Read about a role for the RSR separate from DNA damage signaling in response to sunburn: ✨☀️ www.cell.com/molecular-ce...
The ribotoxic stress response drives acute inflammation, cell death, and epidermal thickening in UV-irradiated skin in vivo
The acute skin reaction to sunburn, encompassing keratinocyte cell death, inflammation, and epidermal thickening, has traditionally been ascribed to DNA damage responses. Using a mouse model deficient...
www.cell.com
November 27, 2024 at 11:23 AM
Are you a scientist working or interested in RNA Translation? Join our starter pack and share ideas, methodologies and tips to advance our knowledge in how life came to be!
#RNA #ribosome

go.bsky.app/VN78eTo
November 24, 2024 at 8:02 PM