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International Society of Nephrology #ThisIsISN • World Congress of Nephrology: #ISNWCN • Young Nephrologists: #ISNyoung • #KidneyHealthMatters • #NephSky
𝗧𝗘𝗦𝗧 𝗬𝗢𝗨𝗥 𝗞𝗡𝗢𝗪𝗟𝗘𝗗𝗚𝗘 by taking the #ISNquiz, developed by
ISNeducation social media committee:
➡️ theisn.outgrow.us/Diabetes_day...
November 14, 2025 at 12:54 PM
17/⏭️To conclude
🆕The integration of innovative pharmacological, genomic, and regenerative strategies can redefine T2DM management
✅It helps to shift the paradigm from symptom control to true disease modification
🎊This is @kajareeg.bsky.social signing off on behalf of @theisn.org education team
November 14, 2025 at 10:27 AM
16/⁉️Want to know how much you are aware of diabetes?
📢Lets take this quiz from the vibrant @theisn.org social media team
@drsumanbehera.bsky.social @myadla.bsky.social

🔗 theisn.outgrow.us/Diabetes_day...
Interactive Calculators & Quizzes
Easily create interactive experiences that increase conversion and bring traffic.
theisn.outgrow.us
November 14, 2025 at 10:27 AM
15/👀Let’s look at the wonderful #visualabstract by @nihalbashir.bsky.social summarizing the key concepts in diabetes
#WorldDiabetesDay
November 14, 2025 at 10:27 AM
14/📌Human islet cell transplantation from deceased donors-established treatment for type 1 diabetes
🏅Scientific progress in the last decade towards deriving pancreatic islet-like cells from human pluripotent stem cells can mitigate demand supply gap
🔗 pubmed.ncbi.nlm.nih.gov/40579550/
November 14, 2025 at 10:27 AM
13/📌Determining the genetic risk for gestational diabetes
🧬Genetic determinants of type 2 diabetes outside of pregnancy are also strong risk factors for gestational diabetes
👀 pubmed.ncbi.nlm.nih.gov/30257980/
November 14, 2025 at 10:27 AM
12/📌Role of BPA in type 2 diabetes risk
🚨It is demonstrated that when BPA is administered to humans in a controlled manner, there is an immediate, direct effect on glucose and insulin levels
⏫It may lead to increased risk of developing type 2 diabetes
🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...
November 14, 2025 at 10:27 AM
11/📌A new target to improve insulin sensitivity
🧬Essential role for ceramides determined as a driver of insulin resistance in mice
🆕New therapeutic strategy for lowering ceramides can reverse insulin resistance
🔗 pubmed.ncbi.nlm.nih.gov/31273070/
November 14, 2025 at 10:27 AM
10/📌What is smart insulin?
🧬Modified insulin that combines insulin and glucagon into one molecule, helping better regulate blood sugar levels and reduce hypoglycemia in type 1 diabetes
✅It mimics the body's natural balance
🔗 pubmed.ncbi.nlm.nih.gov/39414968/
November 14, 2025 at 10:27 AM
9/ 💥Want to know more on newer antidiabetic therapies?
👀Check out the table below
pubmed.ncbi.nlm.nih.gov/40395625/
November 14, 2025 at 10:27 AM
8/📌Orforglipron
⏭️Oral, small-molecule, nonpeptide glucagon-like peptide-1 (GLP-1) receptor agonist investigated for treatment of obesity
💊72-week treatment with orforglipron led to significantly greater reductions in body weight than placebo
🔗 pubmed.ncbi.nlm.nih.gov/40960239/
November 14, 2025 at 10:27 AM
7/📌Teplizumab
⏭️It is the first immunomodulatory agent licensed by the US FDA (2022) for delaying the onset of T1DM in high-risk adults and children over 8 years old
🆕CD3 antibody which enhance regulatory T-cell activity and promote immune tolerance

🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...
November 14, 2025 at 10:27 AM
6/📌New drugs
🆕In recent years, a range of new antidiabetic medications has been developed
🌟These emerging therapies help lower blood sugar and target the metabolic components associated with diabetes
📢Bimagrumab, pramlintide-amylin agonist, pegbelfermin
🔗 pubmed.ncbi.nlm.nih.gov/40395625/
November 14, 2025 at 10:27 AM
5/📌Understanding the biology of body-weight regulation in children
📈The rise in childhood obesity has made this more urgent
👀Study showed that hormonal responses in obese children are normal following a meal, but responses within the brain are ⏬

🔗 pubmed.ncbi.nlm.nih.gov/30418574/
November 14, 2025 at 10:27 AM
4/📌Identification of a new player in Type 1 diabetes
⏭️Genetics+ environment play key role
🧬Proteins called Hybrid Insulin Peptides (HIPs) are found on beta-cells of people with type 1 diabetes and are recognized foreign by their immune cells
🔗 pubmed.ncbi.nlm.nih.gov/31175101/
@who.int
November 14, 2025 at 10:27 AM
3/⏭️4 in 5 people living with diabetes experience diabetes burnout
🚨3 in 4 people living with diabetes experience anxiety, depression or other mental health condition because of their diabetes
🆕In this #skeetorial we will focus on some recent advances in the field of diabetes
#WorldDiabetesDay
November 14, 2025 at 10:27 AM
2b/✅The correct answer is D again!
worlddiabetesday.org
November 14, 2025 at 10:27 AM
2a/⏭️The campaign focus for 14th November is ‘Diabetes and wellbeing’
🫂With appropriate access to care and support for their wellbeing, lets start the change for a better #DiabetesLife
⁉️Do you know how many people living with diabetes are of working age?

➡️4 in 10
➡️5 in 10
➡️6 in 10
➡️7 in 10
November 14, 2025 at 10:27 AM
1b/✅The correct answer is d
#WorldDiabetesDay
worlddiabetesday.org
November 14, 2025 at 10:27 AM
🎧 Join us 𝗧𝗢𝗗𝗔𝗬 for an XSpace: “#KidneyHealthMatters in Diabetes – World Diabetes Day.”

🗣️ Roberto Pecoits-Filho, @kidneydoctor.bsky.social, Manvir Victor
👥 Manjusha Yadla, @dilushiwijay.bsky.social, @drsumanbehera.bsky.social
🕒 1:30 pm CET

🔗 Set your reminder: twitter.com/i/spaces...
November 14, 2025 at 9:00 AM
Protecting kidney health means taking action on diabetes. Early detection and integrated care can save millions of lives.

📊 Download the "Diabetes and Kidney Disease" infographic here: http://lite.spr.ly/6... #WDD
November 14, 2025 at 9:00 AM