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International Society of Nephrology #ThisIsISN • World Congress of Nephrology: #ISNWCN • Young Nephrologists: #ISNyoung • #KidneyHealthMatters • #NephSky
🎥 Explore the onconephrology case presentation series on the ISN Academy, in collaboration with ASON.

Tackle real-world challenges in cancer & kidney care.

📌 Latest case: Onco-hypertension
👉academy.theisn.org/o...
November 15, 2025 at 6:00 AM
𝗧𝗘𝗦𝗧 𝗬𝗢𝗨𝗥 𝗞𝗡𝗢𝗪𝗟𝗘𝗗𝗚𝗘 by taking the #ISNquiz, developed by
ISNeducation social media committee:
➡️ theisn.outgrow.us/Diabetes_day...
November 14, 2025 at 12:54 PM
17/⏭️To conclude
🆕The integration of innovative pharmacological, genomic, and regenerative strategies can redefine T2DM management
✅It helps to shift the paradigm from symptom control to true disease modification
🎊This is @kajareeg.bsky.social signing off on behalf of @theisn.org education team
November 14, 2025 at 10:27 AM
15/👀Let’s look at the wonderful #visualabstract by @nihalbashir.bsky.social summarizing the key concepts in diabetes
#WorldDiabetesDay
November 14, 2025 at 10:27 AM
14/📌Human islet cell transplantation from deceased donors-established treatment for type 1 diabetes
🏅Scientific progress in the last decade towards deriving pancreatic islet-like cells from human pluripotent stem cells can mitigate demand supply gap
🔗 pubmed.ncbi.nlm.nih.gov/40579550/
November 14, 2025 at 10:27 AM
13/📌Determining the genetic risk for gestational diabetes
🧬Genetic determinants of type 2 diabetes outside of pregnancy are also strong risk factors for gestational diabetes
👀 pubmed.ncbi.nlm.nih.gov/30257980/
November 14, 2025 at 10:27 AM
12/📌Role of BPA in type 2 diabetes risk
🚨It is demonstrated that when BPA is administered to humans in a controlled manner, there is an immediate, direct effect on glucose and insulin levels
⏫It may lead to increased risk of developing type 2 diabetes
🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...
November 14, 2025 at 10:27 AM
11/📌A new target to improve insulin sensitivity
🧬Essential role for ceramides determined as a driver of insulin resistance in mice
🆕New therapeutic strategy for lowering ceramides can reverse insulin resistance
🔗 pubmed.ncbi.nlm.nih.gov/31273070/
November 14, 2025 at 10:27 AM
10/📌What is smart insulin?
🧬Modified insulin that combines insulin and glucagon into one molecule, helping better regulate blood sugar levels and reduce hypoglycemia in type 1 diabetes
✅It mimics the body's natural balance
🔗 pubmed.ncbi.nlm.nih.gov/39414968/
November 14, 2025 at 10:27 AM
9/ 💥Want to know more on newer antidiabetic therapies?
👀Check out the table below
pubmed.ncbi.nlm.nih.gov/40395625/
November 14, 2025 at 10:27 AM
8/📌Orforglipron
⏭️Oral, small-molecule, nonpeptide glucagon-like peptide-1 (GLP-1) receptor agonist investigated for treatment of obesity
💊72-week treatment with orforglipron led to significantly greater reductions in body weight than placebo
🔗 pubmed.ncbi.nlm.nih.gov/40960239/
November 14, 2025 at 10:27 AM
7/📌Teplizumab
⏭️It is the first immunomodulatory agent licensed by the US FDA (2022) for delaying the onset of T1DM in high-risk adults and children over 8 years old
🆕CD3 antibody which enhance regulatory T-cell activity and promote immune tolerance

🔗 pmc.ncbi.nlm.nih.gov/articles/PMC...
November 14, 2025 at 10:27 AM
6/📌New drugs
🆕In recent years, a range of new antidiabetic medications has been developed
🌟These emerging therapies help lower blood sugar and target the metabolic components associated with diabetes
📢Bimagrumab, pramlintide-amylin agonist, pegbelfermin
🔗 pubmed.ncbi.nlm.nih.gov/40395625/
November 14, 2025 at 10:27 AM
5/📌Understanding the biology of body-weight regulation in children
📈The rise in childhood obesity has made this more urgent
👀Study showed that hormonal responses in obese children are normal following a meal, but responses within the brain are ⏬

🔗 pubmed.ncbi.nlm.nih.gov/30418574/
November 14, 2025 at 10:27 AM
4/📌Identification of a new player in Type 1 diabetes
⏭️Genetics+ environment play key role
🧬Proteins called Hybrid Insulin Peptides (HIPs) are found on beta-cells of people with type 1 diabetes and are recognized foreign by their immune cells
🔗 pubmed.ncbi.nlm.nih.gov/31175101/
@who.int
November 14, 2025 at 10:27 AM
3/⏭️4 in 5 people living with diabetes experience diabetes burnout
🚨3 in 4 people living with diabetes experience anxiety, depression or other mental health condition because of their diabetes
🆕In this #skeetorial we will focus on some recent advances in the field of diabetes
#WorldDiabetesDay
November 14, 2025 at 10:27 AM
2b/✅The correct answer is D again!
worlddiabetesday.org
November 14, 2025 at 10:27 AM
1b/✅The correct answer is d
#WorldDiabetesDay
worlddiabetesday.org
November 14, 2025 at 10:27 AM
🎧 Join us 𝗧𝗢𝗗𝗔𝗬 for an XSpace: “#KidneyHealthMatters in Diabetes – World Diabetes Day.”

🗣️ Roberto Pecoits-Filho, @kidneydoctor.bsky.social, Manvir Victor
👥 Manjusha Yadla, @dilushiwijay.bsky.social, @drsumanbehera.bsky.social
🕒 1:30 pm CET

🔗 Set your reminder: twitter.com/i/spaces...
November 14, 2025 at 9:00 AM
Protecting kidney health means taking action on diabetes. Early detection and integrated care can save millions of lives.

📊 Download the "Diabetes and Kidney Disease" infographic here: http://lite.spr.ly/6... #WDD
November 14, 2025 at 9:00 AM
📖 This weekend don't miss our @kidneyint.bsky.social #ISNFridaySelection: Childhood-onset lupus nephritis: unique aspects and challenges in management www.kidney-internati...
November 14, 2025 at 6:00 AM
🔹in Kidney International Reports: "Perspectives of transplant professionals on gender differences in living kidney donation."

New insights into gender differences in living kidney donation. Experts highlight the need for strategies to promote gender equity in donation.
🔗 www.kireports.org/ar...
November 13, 2025 at 11:06 AM
🔹in Kidney International: "Management recommendations for kidney transplantation in patients with plasma cell dyscrasia."

A multidisciplinary panel now recommends considering kidney transplantation for selected patients with plasma cell dyscrasia
🔗 www.kidney-internati...
November 13, 2025 at 11:05 AM
🧰 The ISN Early CKD Detection Toolbox helps you design and sustain screening programs.
This toolbox is part of a broader resource developed by ISN and KDIGO, linking key steps to practical, evidence-based resources—adaptable to all settings.
➡️ http://lite.spr.ly/6...
November 13, 2025 at 6:00 AM
The team from Fujita Health University can’t wait to welcome you to WCN’26 in Yokohama, Japan! 🇯🇵

Have you registered yet? Join us and take advantage of early bird rates 👉 lite.spr.ly/60043pXO #ISNWCN
November 12, 2025 at 5:36 PM