Julian Knerr
Julian Knerr
@theforminator.bsky.social
Reposted by Julian Knerr
Nuclear rupture in confined cell migration triggers nuclear actin polymerization to limit chromatin leakage
DDR sensor ATR protects against nuclear envelope rupture via formin phosphorylation inducing F-actin formation
Christos Kamaras et al @grosselab.bsky.social
www.embopress.org/doi/full/10....
September 22, 2025 at 9:04 AM
Reposted by Julian Knerr
Hi all, check out our new preprint where we uncover:"Regulation of YAP activity by nuclear G-actin binding", www.biorxiv.org/cgi/content/...
#actin #YAP/TAZ #transcription #nucleus with help from Sonja-Verena Albers
‪@archaellum.bsky.social‬
Regulation of YAP activity by nuclear G-actin binding
The Yes-associated protein YAP belongs to the TEAD (TEA/ATTS domain) transcriptional co-activators that shuttle between cytoplasm and nuclear compartment. YAP and its paralog TAZ (transcriptional co-a...
www.biorxiv.org
July 31, 2025 at 6:34 AM