Bassem Mohammed
@thecoagmavrick.bsky.social
Pharmacist | Scientist | Optmisit | Coagulation | Research | I wrote this
We are building our team. Got a PhD on a cogualtion related topic. Come join us slu.wd5.myworkdayjobs.com/Careers/job/...
Post Doctoral Fellow - Hemostasis & Thrombosis
Who is Saint Louis University? Founded in 1818, Saint Louis University is one of the nation’s oldest and most prestigious Catholic universities. SLU, which also has a campus in Madrid, Spain, is recog...
slu.wd5.myworkdayjobs.com
September 13, 2025 at 10:02 PM
We are building our team. Got a PhD on a cogualtion related topic. Come join us slu.wd5.myworkdayjobs.com/Careers/job/...
Electrostatic handshake drive factor Va cleavage at R506 by Activated protein C.
Cryo-EM structure of coagulation factor Va bound to activated protein C
Coagulation factor Va (fVa) is the cofactor component of the prothrombinase complex required for rapid generation of thrombin from prothrombin in the …
www.sciencedirect.com
April 29, 2025 at 11:33 AM
Electrostatic handshake drive factor Va cleavage at R506 by Activated protein C.
Reposted by Bassem Mohammed
👥 Meet the future of thrombosis and hemostasis research. In "Leading from the Start", we highlight the pivotal role of the ISTH SSC and its Early Career Co-Chairs—emerging leaders who are already making a global impact.
Read more here: bit.ly/3XOmNCI
Read more here: bit.ly/3XOmNCI
April 7, 2025 at 6:30 PM
👥 Meet the future of thrombosis and hemostasis research. In "Leading from the Start", we highlight the pivotal role of the ISTH SSC and its Early Career Co-Chairs—emerging leaders who are already making a global impact.
Read more here: bit.ly/3XOmNCI
Read more here: bit.ly/3XOmNCI
Reposted by Bassem Mohammed
If you missed our paper on the humanized murine model of VWD-type 1 (hVWD1) you can read it haematologica.org/article/view...
The model provides a novel platform to test therapeutic options for #VWD one of which is explored in the paper! Thanks Haematologica for the highlight as Editor’s pick!
The model provides a novel platform to test therapeutic options for #VWD one of which is explored in the paper! Thanks Haematologica for the highlight as Editor’s pick!
A fully humanized von Willebrand disease type 1 mouse model as unique platform to investigate novel therapeutic options
| Haematologica
haematologica.org
April 1, 2025 at 9:36 PM
If you missed our paper on the humanized murine model of VWD-type 1 (hVWD1) you can read it haematologica.org/article/view...
The model provides a novel platform to test therapeutic options for #VWD one of which is explored in the paper! Thanks Haematologica for the highlight as Editor’s pick!
The model provides a novel platform to test therapeutic options for #VWD one of which is explored in the paper! Thanks Haematologica for the highlight as Editor’s pick!
Congrats to All JTH editor's Award recipients
March 25, 2025 at 12:12 AM
Congrats to All JTH editor's Award recipients
Reposted by Bassem Mohammed
1st attempt, please add to this 😊
go.bsky.app/Cph9GV4
go.bsky.app/Cph9GV4
November 11, 2024 at 9:06 PM
1st attempt, please add to this 😊
go.bsky.app/Cph9GV4
go.bsky.app/Cph9GV4
Reposted by Bassem Mohammed
Welcome @isth-official.bsky.social to 🦋!
To my followers: please follow ISTH for news, education, and community for #Thrombosis & #Hemostasis!
#HemeSky
To my followers: please follow ISTH for news, education, and community for #Thrombosis & #Hemostasis!
#HemeSky
November 26, 2024 at 4:13 PM
Welcome @isth-official.bsky.social to 🦋!
To my followers: please follow ISTH for news, education, and community for #Thrombosis & #Hemostasis!
#HemeSky
To my followers: please follow ISTH for news, education, and community for #Thrombosis & #Hemostasis!
#HemeSky
Reposted by Bassem Mohammed
We’ve extended the early (reduced-price) registration deadline for PolyP-2025, the conference on polyphosphate biology, until April 30!!
Please spread the word about this conference. We have a great lineup of speakers on this emerging field!
polyp2025.org/registration/
Please spread the word about this conference. We have a great lineup of speakers on this emerging field!
polyp2025.org/registration/
March 5, 2025 at 3:33 PM
We’ve extended the early (reduced-price) registration deadline for PolyP-2025, the conference on polyphosphate biology, until April 30!!
Please spread the word about this conference. We have a great lineup of speakers on this emerging field!
polyp2025.org/registration/
Please spread the word about this conference. We have a great lineup of speakers on this emerging field!
polyp2025.org/registration/
Reposted by Bassem Mohammed
Registration is now open for the 2025 NYC CryoEM meeting, organized by Bill Rice (NYU) & @fravallese.bsky.social (CUNY/ASRC)
Always a great meeting with lots of new #cryoem work by rising stars in/around NYC
Max 140 people so register now (it’s free)!
Always a great meeting with lots of new #cryoem work by rising stars in/around NYC
Max 140 people so register now (it’s free)!
Fifth New York Area Cryo-EM Meeting | NYU Langone Health
Join the 2025 Cryo-EM & Cryo-ET Meeting at NYU Langone! Share unpublished work, discuss breakthroughs, and tackle challenges. June 25. Register now!
med.nyu.edu
February 12, 2025 at 12:33 AM
Registration is now open for the 2025 NYC CryoEM meeting, organized by Bill Rice (NYU) & @fravallese.bsky.social (CUNY/ASRC)
Always a great meeting with lots of new #cryoem work by rising stars in/around NYC
Max 140 people so register now (it’s free)!
Always a great meeting with lots of new #cryoem work by rising stars in/around NYC
Max 140 people so register now (it’s free)!
Factor XII (FXII) exists in multiple conformations, with a "closed" form dominating in solution. Surface binding triggers a shift to an "open" form, more primed for activation. AlphaFold-guided studies and single-molecule dynamics shed light on this process!
ashpublications.org/bloodadvance...
ashpublications.org/bloodadvance...
A Model of Zymogen Factor XII: Insights into Protease Activation
Key Points. When not bound to a surface, FXII adopts a “closed” conformation that is resistant to activation by plasma kallikrein.Intramolecular interactio
ashpublications.org
February 3, 2025 at 4:36 AM
Factor XII (FXII) exists in multiple conformations, with a "closed" form dominating in solution. Surface binding triggers a shift to an "open" form, more primed for activation. AlphaFold-guided studies and single-molecule dynamics shed light on this process!
ashpublications.org/bloodadvance...
ashpublications.org/bloodadvance...
Single amino acid replacement can change thrombin substrate preference from trypsin-like to chymotrypsin-like pubmed.ncbi.nlm.nih.gov/39756655/
Replacement of a single residue changes the primary specificity of thrombin - PubMed
D189 in the S1 pocket confers thrombin "trypsin-like" specificity for Arg at P1. However, the S1 pocket is wide enough to also enable "chymotrypsin-like" specificity for Phe at P1. Consistent with the...
pubmed.ncbi.nlm.nih.gov
January 19, 2025 at 8:23 PM
Single amino acid replacement can change thrombin substrate preference from trypsin-like to chymotrypsin-like pubmed.ncbi.nlm.nih.gov/39756655/
Reposted by Bassem Mohammed
Call for Abstracts: PolyP-2025 – Conference on Polyphosphate Biology – May 20-23, 2025. Abstract deadline for oral or poster presentation is March 1; deadline for poster-only presentation is April 1. Early (reduced-cost) registration deadline is February 28, 2025. Full meeting info: polyp2025.org
Frankel Cardiovascular Center, University of Michigan Health
polyp2025.org
January 14, 2025 at 9:44 PM
Call for Abstracts: PolyP-2025 – Conference on Polyphosphate Biology – May 20-23, 2025. Abstract deadline for oral or poster presentation is March 1; deadline for poster-only presentation is April 1. Early (reduced-cost) registration deadline is February 28, 2025. Full meeting info: polyp2025.org
Reposted by Bassem Mohammed
Gave a talk on social media this morning at #ASH24
Someone asked about the longevity of BlueSky and I answered optimistically.
So don’t make me look dumb y’all.
Someone asked about the longevity of BlueSky and I answered optimistically.
So don’t make me look dumb y’all.
December 6, 2024 at 10:43 PM
Gave a talk on social media this morning at #ASH24
Someone asked about the longevity of BlueSky and I answered optimistically.
So don’t make me look dumb y’all.
Someone asked about the longevity of BlueSky and I answered optimistically.
So don’t make me look dumb y’all.