Reposted by Tetsuichi Yoshizato
A new study by @tetsuichi.bsky.social et al published in @natgenet.nature.com shows that human blood #stemcells have stable, intrinsic lineage biases. Some replenish all blood cell types, others only a subset. These patterns persist over decades and after transplantation 🧪 #bloodcancer rdcu.be/ePlJW
Stable clonal contribution of lineage-restricted stem cells to human hematopoiesis
Nature Genetics - This study uses somatic mutations as a natural barcoding system to retrospectively and prospectively trace the fate of hematopoietic stem cells across all major blood cell...
rdcu.be
November 12, 2025 at 8:05 AM
A new study by @tetsuichi.bsky.social et al published in @natgenet.nature.com shows that human blood #stemcells have stable, intrinsic lineage biases. Some replenish all blood cell types, others only a subset. These patterns persist over decades and after transplantation 🧪 #bloodcancer rdcu.be/ePlJW