🔬 We killed GFP. Oops.

The most reliable protein in biology. Zero expression. Same amino acid sequence, different mRNA design.

Most mRNA design sucks.

Disappointed by expression levels? Frustrated by immunogenicity? It’s not bad luck—it’s sequence design.

Those “codon optimized” sequences from established vendors? They’re built for manufacturing convenience, not your therapeutic success.

Your mRNA sequence is silently bleeding your runway dry. Startups are burning $Ms fixing problems they could have avoided for a fraction of the cost. Don't be next. 👇

Low-quality mRNA doesn’t give you “good results with bad quality we can figure out later.” It gives you something else entirely: an experiment that isn’t yours. This adds to timelines, burns cash, and doesn't advance your science.

Learn more about how we make high-quality mRNA:

It’s getting easier and easier to simulate biology, but the work of actually building molecules, developing and manufacturing real medicines remains incredibly challenging.

"RNA manufacturing is still an art, not just a science" - John Evans

Read more about Terrain Bio and the challenge of designing and building high quality RNA for developing new medicines in @statnews.com by Allison DeAngelis

Better RNA is possible. We are Terrain Bio.