Tanavi
@tanavi.bsky.social
Biomedical Scientist | Mass Spectrometry | Proteomics
Melbourne, Australia
Melbourne, Australia
Reposted by Tanavi
We noticed CII assembly factor SDHAF2 accumulates in some OXPHOS deficient cell lines but not others. New Dr Kugan cracked the case: CII assembly controls a balance btwn TCA cycle direction and protection from Q-pool stress to support ROS-meditated metabolic reprogramming in OXPHOS adapted cells.
Complex II assembly drives metabolic adaptation to OXPHOS dysfunction
Succinate dehydrogenase assembly dynamics maintains metabolic homeostasis during mitochondrial oxidative stress.
www.science.org
August 15, 2025 at 9:16 PM
We noticed CII assembly factor SDHAF2 accumulates in some OXPHOS deficient cell lines but not others. New Dr Kugan cracked the case: CII assembly controls a balance btwn TCA cycle direction and protection from Q-pool stress to support ROS-meditated metabolic reprogramming in OXPHOS adapted cells.
Reposted by Tanavi
Proteomics invited me to write a review on Multi-Omics. So we did. Just got accepted an the pre-print is here. Hopefully researchers find it useful. And yes, we did express our opinion on what we thought needs improving. And proteoforms got a mention.
www.authorea.com/users/904760...
www.authorea.com/users/904760...
Sample Preparation for Multi-omics Analysis: Considerations and Guidance for Identifying the Ideal Workflow.
Advances in methodologies and technologies over the previous decade has led to a depth of analysis of a cell’s biomolecules that is unprecedented, with entire genomes able to be sequenced in hours and...
www.authorea.com
June 3, 2025 at 6:16 AM
Proteomics invited me to write a review on Multi-Omics. So we did. Just got accepted an the pre-print is here. Hopefully researchers find it useful. And yes, we did express our opinion on what we thought needs improving. And proteoforms got a mention.
www.authorea.com/users/904760...
www.authorea.com/users/904760...
Reposted by Tanavi
We're super proud to see our study showing utility of proteomics in ultra-rapid variant prioritisation for suspected mito and other rare diseases out in Genome Medicine (rdcu.be/endwE). Too many amazing collabs to thank, so here are the big ones @daniellahock.bsky.social @thorburnmito.bsky.social!
Cutting the diagnosis journey for children born with rare genetic diseases
Families can wait years for a diagnosis of a rare genetic disorder, but a new test can provide answers in days for a better understanding of the condition and potentially earlier treatment, finds new...
pursuit.unimelb.edu.au
May 23, 2025 at 12:57 AM
We're super proud to see our study showing utility of proteomics in ultra-rapid variant prioritisation for suspected mito and other rare diseases out in Genome Medicine (rdcu.be/endwE). Too many amazing collabs to thank, so here are the big ones @daniellahock.bsky.social @thorburnmito.bsky.social!
Reposted by Tanavi
Hi #TeamMassSpec! #FeMS+ has joined BlueSky! Please share and get the word out so we can build up a base here.
November 30, 2024 at 2:00 PM
Hi #TeamMassSpec! #FeMS+ has joined BlueSky! Please share and get the word out so we can build up a base here.