Sho Takeshita 竹下翔
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takeshita-sho.bsky.social
Sho Takeshita 竹下翔
@takeshita-sho.bsky.social
19 followers 190 following 4 posts
A PhD student in Biophysics @JHU. Interested in proteins and deep learning.
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Reposted by Sho Takeshita 竹下翔
biorxiv-biophys.bsky.social
Transforming macromolecular structures into simulations of self-assembly https://www.biorxiv.org/content/10.64898/2026.01.27.702082v1
January 29, 2026 at 12:46 AM
Reposted by Sho Takeshita 竹下翔
biorxiv-biophys.bsky.social
A membrane-driven biochemical oscillator tunable by the volume to surface area ratio https://www.biorxiv.org/content/10.1101/2025.11.14.688573v1
November 16, 2025 at 10:47 PM
Reposted by Sho Takeshita 竹下翔
samuelfoley.com
This is a rather unfortunate change that seems to have come as a surprise to just about everyone. FYI for students and PIs who were looking to apply for the NSF GRFP
dangaristo.bsky.social Dan Garisto @dangaristo.bsky.social · Sep 26
As others have pointed out, the fellowship is now available only to 1st year grad students. (Left is last year, right is this year)
Be a U.S. citizen, national, or permanent resident Intend to enroll or be enrolled full-time in a research-based Master's or doctoral degree program in an eligible Field of Study in STEM or STEM education (See Appendix and Section IV.3 for eligible Fields of Study Never previously accepted a Graduate Research Fellowship Declined any previously offered Graduate Research Fellowship by the acceptance deadline Never previously applied to GRFP while enrolled in a graduate degree program Never earned a doctoral or terminal degree in any field Have completed no more than one academic year (according to institution's academic calendar) while enrolled in a graduate degree program (non-degree coursework must be clearly identified in the transcript and does not count toward this limit) Individuals holding joint Bachelor's-Master's degrees who did not apply while enrolled in the joint program, may apply as second-year graduate applicants if enrolled in an eligible doctoral program the beginning of the academic year immediately following the academic award year of the joint degree Individuals with prior graduate enrollment who have: (i) completed more than one academic year in any graduate degree-granting program, (ii) earned a previous master's degree of any kind (see guidance for joint Bachelor's-Master's degree-holders above), or (iii) earned a professional degree must meet the following requirements: not enrolled in a graduate degree program at application deadline two or more consecutive years past graduate degree enrollment or completion at the application deadline Not be a current NSF employee. Must, at the time of submission, be a U.S. citizen, national, or a permanent resident (“green-card” holder) Must intend to enroll or be enrolled in an eligible research-based master's or doctoral degree program in an eligible field of study in STEM, including STEM education (See Appendix and Section IV.3 for eligible Fields of Study); Never have previously accepted a Graduate Research Fellowship; Have declined any previously offered Graduate Research Fellowship by the declination deadline (if applicable); Have completed less than one academic year in a graduate degree program (according to the institution’s academic calendar; non-degree coursework must be clearly identified in the transcript and does not count toward this limit). This means individuals in the following statuses at the time of application are eligible: Undergraduate in the final (senior) year of a bachelor’s degree program Bachelor’s degree-holder with NO enrollment in a graduate degree program (non-degree graduate coursework allowed) Individual enrolled in a joint bachelor’s-master’s degree program with at least three undergraduate years completed First-year graduate student in their first graduate degree program with less than one academic year completed in the degree program (according to institution’s academic calendar) Individuals enrolled in joint bachelor’s-master’s degree programs are considered graduate students. For GRFP, joint bachelor’s-master’s degrees are defined as degrees concurrently pursued and awarded. Not be a current NSF employee.
September 26, 2025 at 5:09 PM
Reposted by Sho Takeshita 竹下翔
pratted.bsky.social
Announcing such a major change to NSF GRFP this late in the cycle is incredibly cruel. 2nd yr students (mine included) have been working so hard on their proposals despite ongoing uncertainty. They are driven and passionate about being outstanding scientists and helping those coming up behind them.
This means individuals in the following statuses at the time of application are eligible: Undergraduate in the final (senior) year of a bachelor’s degree program Bachelor’s degree-holder with NO enrollment in a graduate degree program (non-degree graduate coursework allowed) Individual enrolled in a joint bachelor’s-master’s degree program with at least three undergraduate years completed First-year graduate student in their first graduate degree program with less than one academic year completed in the degree program (according to institution’s academic calendar) Individuals enrolled in joint bachelor’s-master’s degree programs are considered graduate students. For GRFP, joint bachelor’s-master’s degrees are defined as degrees concurrently pursued and awarded. Not be a current NSF employee. Applications that do not meet eligibility requirements will be returned without review as being ineligible for a fellowship.
September 26, 2025 at 5:46 PM
takeshita-sho.bsky.social
Check out this cool manuscript I was a part of!
swcanner.bsky.social Samuel William Canner @swcanner.bsky.social · Sep 8
My latest manuscript is now on BioRxiv: Evaluation of De Novo Deep Learning Models on the Protein-Sugar Interactome. where we benchmark AF3 at protein-carbohydrate docking. This work was only possible with Dr. Lei Lu @takeshita-sho.bsky.social and @jeffreyjgray.bsky.social
doi.org/10.1101/2025...
September 8, 2025 at 6:03 PM
Reposted by Sho Takeshita 竹下翔
biorxiv-biophys.bsky.social
Evaluation of De Novo Deep Learning Models on the Protein-Sugar Interactome https://www.biorxiv.org/content/10.1101/2025.09.02.673778v1
September 7, 2025 at 12:48 AM
Reposted by Sho Takeshita 竹下翔
mejohnson81.bsky.social
Does protein dimerization always help targeting and dwell time on DNA? Not for a population! Dwell time is especially sensitive to spacing between DNA targets. Nonspecific binding and facilitated (1D) diffusion also play a key role. Super proud of Mankun Sang’s work!
doi.org/10.1101/2025...
Proteins can form dimers and bind DNA specifically and nonspecifically, exploiting 3D and 1D diffusion. This can drives both enhanced and impaired dwell time and target occupancy depending on spacing between specific targets.
July 11, 2025 at 4:23 PM