SvenssonLab
@svenssonlab.bsky.social
We study secreted peptides and regulation of energy balance 🧠
PI: Katrin J. Svensson Associate Professor at Stanford Pathology and Metabolic Core Director at Stanford DRC
www.svenssonlabstanford.org
#obesity #peptides #secretome #neurometabolism #adipose
PI: Katrin J. Svensson Associate Professor at Stanford Pathology and Metabolic Core Director at Stanford DRC
www.svenssonlabstanford.org
#obesity #peptides #secretome #neurometabolism #adipose
Grateful to the American Diabetes Association @amdiabetesassn.bsky.social for the opportunity to make a short film about our lab at Stanford University. We talk about peptides and their roles in metabolic health.
youtu.be/qUjYPTN09mI?...
See you at ADA 2025 in Chicago
youtu.be/qUjYPTN09mI?...
See you at ADA 2025 in Chicago
Decoding the Dark Peptidome – Svensson Lab, Stanford University
YouTube video by WebsEdgeMedicine
youtu.be
June 21, 2025 at 6:50 PM
Grateful to the American Diabetes Association @amdiabetesassn.bsky.social for the opportunity to make a short film about our lab at Stanford University. We talk about peptides and their roles in metabolic health.
youtu.be/qUjYPTN09mI?...
See you at ADA 2025 in Chicago
youtu.be/qUjYPTN09mI?...
See you at ADA 2025 in Chicago
Sharing our latest review on peptide hormones in Trends in Biochemical Sciences
Free full text here:
www.sciencedirect.com/science/arti...
Free full text here:
www.sciencedirect.com/science/arti...
Understanding peptide hormones: from precursor proteins to bioactive molecules
Peptide hormones are fundamental regulators of biological processes involved in homeostasis regulation and are often dysregulated in endocrine disease…
www.sciencedirect.com
April 16, 2025 at 3:42 AM
Sharing our latest review on peptide hormones in Trends in Biochemical Sciences
Free full text here:
www.sciencedirect.com/science/arti...
Free full text here:
www.sciencedirect.com/science/arti...
Today in @Nature, we share our latest paper. We developed an algorithm to predict novel peptides cleaved by proconvertases across all human tissues. Using this method, we identified BRP, a brain-derived anti-obesity peptide 🧠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide - Nature
Computational drug discovery is used to identify a 12-mer peptide derived from BRINP2 with potent anti-obesity effects that are independent of leptin, glucagon-like peptide 1 receptor and melanocortin...
www.nature.com
March 5, 2025 at 6:31 PM
Today in @Nature, we share our latest paper. We developed an algorithm to predict novel peptides cleaved by proconvertases across all human tissues. Using this method, we identified BRP, a brain-derived anti-obesity peptide 🧠
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by SvenssonLab
new out in Nature www.nature.com/articles/s41...
Cooperative nutrient scavenging is an evolutionary advantage in cancer - Nature
Nutrient-starved tumour cells cooperate by secreting aminopeptidases that digest oligopeptides in the microenvironment, creating a shared pool of free amino acids.
www.nature.com
February 20, 2025 at 8:25 AM
new out in Nature www.nature.com/articles/s41...
Congratulations to Zeyuan for winning the travel prize! Thank you LifeMetabolism for supporting his work!
LIFE METABOLISM Travel prizes
@lifemetabolism.bsky.social
Sponsored by
@sablesys.bsky.social
Our 3rd winner is Zeyuan Zhang from Stanford who will present his work on novel products of the CART gene at the Metabolic signalling cold spring harbor meeting
Congrats...
@lifemetabolism.bsky.social
Sponsored by
@sablesys.bsky.social
Our 3rd winner is Zeyuan Zhang from Stanford who will present his work on novel products of the CART gene at the Metabolic signalling cold spring harbor meeting
Congrats...
January 23, 2025 at 3:52 AM
Congratulations to Zeyuan for winning the travel prize! Thank you LifeMetabolism for supporting his work!
Reposted by SvenssonLab
#YearInReview A new understanding of how ketosis is linked to body weight regulation: https://buff.ly/3ZOkoId
December 27, 2024 at 6:00 PM
#YearInReview A new understanding of how ketosis is linked to body weight regulation: https://buff.ly/3ZOkoId
Sharing our receng paper in Cell Systems that demonstrates how AlphaFold can predict the binding between ligands and cell surface receptors. Congrats Niels and co-authors from K.C. Garcia lab
#alphafold
See paper here: cell.com/cell-systems/a…
#alphafold
See paper here: cell.com/cell-systems/a…
https://cell.com/cell-systems/a…
November 18, 2024 at 3:51 AM
Sharing our receng paper in Cell Systems that demonstrates how AlphaFold can predict the binding between ligands and cell surface receptors. Congrats Niels and co-authors from K.C. Garcia lab
#alphafold
See paper here: cell.com/cell-systems/a…
#alphafold
See paper here: cell.com/cell-systems/a…
Reposted by SvenssonLab
Stephen Zhang and the team found that in vivo peptide release and signaling gradually enhances responses of satiety-promoting hypothalamic neurons to each bite of food. These consequences of each bite take minutes to manifest, and could help explain why slow eating enhances satiety. rdcu.be/dZlI3
Stochastic neuropeptide signals compete to calibrate the rate of satiation
Nature - Release of hunger-promoting and satiety-promoting neuropeptides drives opposing changes in the second messenger cAMP in awake mouse paraventricular hypothalamic MC4R neurons, thereby...
rdcu.be
November 16, 2024 at 11:41 AM
Stephen Zhang and the team found that in vivo peptide release and signaling gradually enhances responses of satiety-promoting hypothalamic neurons to each bite of food. These consequences of each bite take minutes to manifest, and could help explain why slow eating enhances satiety. rdcu.be/dZlI3