Susana Simões-Sousa
@susana-sousa.bsky.social
Postdoctoral Training Fellow @thedownslab.bsky.social @icr.ac.uk
The Downs Lab website: thedownslab.org
The Downs Lab website: thedownslab.org
Our latest work is now out in Cell Reports!
Now out! Led by @susana-sousa.bsky.social and Noa Amin, and thanks to our collaborators in the Harrington @icr.ac.uk and Stucki and Choudhary @jc4-jyoti.bsky.social labs
www.cell.com/cell-reports...
www.cell.com/cell-reports...
September 17, 2025 at 8:52 AM
Our latest work is now out in Cell Reports!
Reposted by Susana Simões-Sousa
@kezlane.bsky.social Karen Lane presented work she did with @susana-sousa.bsky.social and Noa Amin on ARID1A and G4s (not her main project - watch this space for a project coming out soon on cohesin dynamics in SWI/SNF deficient cells)
July 4, 2025 at 2:09 PM
@kezlane.bsky.social Karen Lane presented work she did with @susana-sousa.bsky.social and Noa Amin on ARID1A and G4s (not her main project - watch this space for a project coming out soon on cohesin dynamics in SWI/SNF deficient cells)
Reposted by Susana Simões-Sousa
New preprint from the lab on ARID1A, G quadruplexes, and repair:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
ARID1A stabilises non-homologous end joining factors at DNA breaks induced by the G4 ligand pyridostatin
ARID1A is a subunit of the BAF chromatin remodelling complex that is frequently mutated in cancer. It is challenging to predict how ARID1A loss impacts cancer therapy response because it participates ...
www.biorxiv.org
May 27, 2025 at 5:32 PM
New preprint from the lab on ARID1A, G quadruplexes, and repair:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...