Suparna Kumar
@sups-k.bsky.social
PhD Candidate at @weillcornell.bsky.social in the @wcm-imp.bsky.social program. Researching #lupus at @theresalulab.bsky.social
Reposted by Suparna Kumar
Don’t miss this week’s issue of #ScienceSignaling!
New discoveries about an enigmatic, cancer-linked mutation could redefine understanding of the kinome, a study reveals how immune cells are recruited to inflammatory sites in psoriasis, and more. https://scim.ag/3LkFGtC
New discoveries about an enigmatic, cancer-linked mutation could redefine understanding of the kinome, a study reveals how immune cells are recruited to inflammatory sites in psoriasis, and more. https://scim.ag/3LkFGtC
November 4, 2025 at 10:00 PM
Don’t miss this week’s issue of #ScienceSignaling!
New discoveries about an enigmatic, cancer-linked mutation could redefine understanding of the kinome, a study reveals how immune cells are recruited to inflammatory sites in psoriasis, and more. https://scim.ag/3LkFGtC
New discoveries about an enigmatic, cancer-linked mutation could redefine understanding of the kinome, a study reveals how immune cells are recruited to inflammatory sites in psoriasis, and more. https://scim.ag/3LkFGtC
Reposted by Suparna Kumar
Our paper is out! Kudos to 1st authors Mir Howlader, who received a @weillcornell.bsky.social Rachele Prize for this work, former Peds Rheum fellow William Ambler, and all co-authors! @jclinical-invest.bsky.social @wcm-imp.bsky.social @lupusresearch.bsky.social #lymphatic #stromal #photosensitivity
Lymphatic dysfunction in lupus contributes to cutaneous photosensitivity and lymph node B cell responses @jclinical-invest.bsky.social @theresalulab.bsky.social
www.jci.org/articles/vie...
www.jci.org/articles/vie...
June 22, 2025 at 9:00 PM
Our paper is out! Kudos to 1st authors Mir Howlader, who received a @weillcornell.bsky.social Rachele Prize for this work, former Peds Rheum fellow William Ambler, and all co-authors! @jclinical-invest.bsky.social @wcm-imp.bsky.social @lupusresearch.bsky.social #lymphatic #stromal #photosensitivity
Reposted by Suparna Kumar
An authoritative review on phagosome immunobiology by David Underhill and Kai Li. Highly recommend for anyone interested in innate immunity, antigen presentation, infection and host defense.
@cedarssinai.bsky.social
rdcu.be/eNIFY
@cedarssinai.bsky.social
rdcu.be/eNIFY
Phagocytosis: a process that shapes immune responses to engulfed meals
Nature Reviews Immunology - In this Review, Li and Underhill discuss recent advances in understanding the process of phagocytosis. The authors highlight how phagocytosis is integral for innate...
rdcu.be
October 31, 2025 at 7:22 PM
An authoritative review on phagosome immunobiology by David Underhill and Kai Li. Highly recommend for anyone interested in innate immunity, antigen presentation, infection and host defense.
@cedarssinai.bsky.social
rdcu.be/eNIFY
@cedarssinai.bsky.social
rdcu.be/eNIFY
Reposted by Suparna Kumar
This paper validates the original work establishing this concept for the cGAS-STING pathway. Kudos to the authors.
@wyssinstitute.bsky.social
journals.asm.org/doi/10.1128/...
@wyssinstitute.bsky.social
journals.asm.org/doi/10.1128/...
mRNAs encoding self-DNA reactive cGAS enhance the immunogenicity of lipid nanoparticle vaccines | mBio
Nucleic acid-based vaccines hold promise in preventing infections and treating cancer.
The most common use of this technology is to encode antigenic proteins on mRNAs that
are delivered to cells via l...
journals.asm.org
November 4, 2025 at 3:31 PM
This paper validates the original work establishing this concept for the cGAS-STING pathway. Kudos to the authors.
@wyssinstitute.bsky.social
journals.asm.org/doi/10.1128/...
@wyssinstitute.bsky.social
journals.asm.org/doi/10.1128/...
Reposted by Suparna Kumar
Evidence continues to accumulate that mRNA can deliver immunostimulatory innate proteins.
www.pnas.org/doi/suppl/10...
www.pnas.org/doi/suppl/10...
November 4, 2025 at 3:31 PM
Evidence continues to accumulate that mRNA can deliver immunostimulatory innate proteins.
www.pnas.org/doi/suppl/10...
www.pnas.org/doi/suppl/10...