Gokul Upadhyayula
supgokul.bsky.social
Gokul Upadhyayula
@supgokul.bsky.social
Opinions my own
This work was made possible in part by support from
@czbiohub.bsky.social @cziscience.bsky.social
@sloanfoundation.bsky.social, @berkeleylab.lbl.gov, @hhmi.org, @nersc.bsky.social, Philomathia Foundation and NIH.
October 17, 2025 at 1:04 AM
Thrilled to share our Science cover! VIPS (volumetric imaging via photochemical sectioning) eliminates working-distance limits for whole-mount, nanoscale imaging. LLSM + photodegradable hydrogel + petabyte-scale compute → mapped axons & myelin across two mouse olfactory bulbs (WT vs NPC1).
October 17, 2025 at 12:30 AM
Finally here! Our preprint on the MOSAIC, a multimodal adaptive optical microscope enabling non‑invasive in‑vivo imaging from molecules to organisms, is out. MOSAIC captures everything from subcellular dynamics to neural activity in live mice.
www.biorxiv.org/content/10.1...
June 16, 2025 at 9:26 PM