Siân Culley
@superresolusian.bsky.social
Still seeking M. Ulder for joint author paper.
Microscopes ✅ cats ✅ combining the two ❌
Lab --> https://www.kcl.ac.uk/research/culley-group
Microscopes ✅ cats ✅ combining the two ❌
Lab --> https://www.kcl.ac.uk/research/culley-group
BioImage analysis friends - King's are recruiting for a full-time, permanent facility position! Come and work with fun microscopes and fun people (and me!) - please share! www.kcl.ac.uk/jobs/126345-...
Bioimage Analysis Specialist | King's College London
www.kcl.ac.uk
September 29, 2025 at 9:48 AM
BioImage analysis friends - King's are recruiting for a full-time, permanent facility position! Come and work with fun microscopes and fun people (and me!) - please share! www.kcl.ac.uk/jobs/126345-...
This is suuuuper cool! Quantitative modelling of structures in fluorescence microscopy images across several orders of magnitude 👀
How do you quantify cell structures which are deformed between different observations? Our preprint shows how to perform Simultaneous QUAntification of Structure and Structural Heterogeneity (SQUASSH) on 3D fluorescence microscopy data. (1/5)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Extracting biological structure and heterogeneity from the nano to the macro scale
Fluorescence microscopy is an essential tool in biology. It has revealed great variability at multiple scales, in macromolecular complexes, cells, and organisms. Understanding this variability will re...
www.biorxiv.org
August 12, 2025 at 4:46 PM
This is suuuuper cool! Quantitative modelling of structures in fluorescence microscopy images across several orders of magnitude 👀
Hello! Very excited to share our latest preprint, which is great news for us but terrible news for any diehard fans of PSNR and SSIM as image quality metrics in microscopy... (1/5)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Image quality metrics fail to accurately represent biological information in fluorescence microscopy
Image processing methods offer the potential to improve the quality of fluorescence microscopy data, allowing for image acquisition at lower, less phototoxic illumination doses. The training and evalu...
www.biorxiv.org
August 7, 2025 at 1:00 PM
Hello! Very excited to share our latest preprint, which is great news for us but terrible news for any diehard fans of PSNR and SSIM as image quality metrics in microscopy... (1/5)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Had a great time teaching on #SOMC25, including my first ever field trip and resultant microscope-based exposure therapy to try and cure myself of my irrational crustacean phobia
July 30, 2025 at 5:38 PM
Had a great time teaching on #SOMC25, including my first ever field trip and resultant microscope-based exposure therapy to try and cure myself of my irrational crustacean phobia
I love everything about this relic I just found at my parents' house. My great uncle Donald met Valentina Tereshkova! Look how happy he is! Look how unimpressed she is with Concorde when she has been into been into actual literal space! Look how mansplainy the caption is!
December 25, 2024 at 10:52 AM
I love everything about this relic I just found at my parents' house. My great uncle Donald met Valentina Tereshkova! Look how happy he is! Look how unimpressed she is with Concorde when she has been into been into actual literal space! Look how mansplainy the caption is!
London microscopy folk - does anyone have an old-school SIM (rather than an iSIM/Sora/Airyscan) that we could have a look at some expanded samples on? Our STED is dead (which rhymes but is also sad) so we're hunting for another system 👀
December 10, 2024 at 1:54 PM
London microscopy folk - does anyone have an old-school SIM (rather than an iSIM/Sora/Airyscan) that we could have a look at some expanded samples on? Our STED is dead (which rhymes but is also sad) so we're hunting for another system 👀
Putting the AAAAARRRRRRGGGGHHHH into OME-Zarr
December 3, 2024 at 3:01 PM
Putting the AAAAARRRRRRGGGGHHHH into OME-Zarr
Turns out that it's even easier to apply if you have the correct link to follow 🤠
CORRECT LINK: www.jobs.ac.uk/job/DKU906/p...
CORRECT LINK: www.jobs.ac.uk/job/DKU906/p...
November 29, 2024 at 6:28 PM
Turns out that it's even easier to apply if you have the correct link to follow 🤠
CORRECT LINK: www.jobs.ac.uk/job/DKU906/p...
CORRECT LINK: www.jobs.ac.uk/job/DKU906/p...
An early Christmas present if you like Fluorescence Lifetime Imaging Microscopy, data analysis and pho-ho-ho-tons (sorry not sorry) - another postdoc position open in my group! Deadline 16th December -> www.kcl.ac.uk/jobs/100785-...
Part of a super fun and collaborative Wellcome Bioimaging project 🔬
Part of a super fun and collaborative Wellcome Bioimaging project 🔬
www.kcl.ac.uk
November 29, 2024 at 11:58 AM
An early Christmas present if you like Fluorescence Lifetime Imaging Microscopy, data analysis and pho-ho-ho-tons (sorry not sorry) - another postdoc position open in my group! Deadline 16th December -> www.kcl.ac.uk/jobs/100785-...
Part of a super fun and collaborative Wellcome Bioimaging project 🔬
Part of a super fun and collaborative Wellcome Bioimaging project 🔬
I am of course delighted to be here.
November 29, 2024 at 11:51 AM
I am of course delighted to be here.