Steve Joffe
@stevejoffe.bsky.social
Professor @ UPenn. Research ethics, pediatric ethics, cancer ethics, genomethics, science policy. Grateful immigrant, he/him. Speak only for myself. Reposts do not imply endorsement.
ORCID ID: 0000-0002-0667-7384
ORCID ID: 0000-0002-0667-7384
Reposted by Steve Joffe
Working on a project about AI and trust in historically marginalized communities and need your voices. 🙏 If you’re open to sharing your views (and maybe a short video), please take this quick survey and share widely. Selected video contributors get a $25 gift card. 💳🗣️ Link: forms.gle/RFvedx2e2Lmd...
November 22, 2025 at 1:55 PM
Working on a project about AI and trust in historically marginalized communities and need your voices. 🙏 If you’re open to sharing your views (and maybe a short video), please take this quick survey and share widely. Selected video contributors get a $25 gift card. 💳🗣️ Link: forms.gle/RFvedx2e2Lmd...
Reposted by Steve Joffe
By @markhertling.bsky.social:
www.thebulwark.com/p/what-ameri... Clarifying duties (plural) of military personnel toward unlawful orders. "Officers are duty-bound to refuse an unlawful order. It is not optional. It is not situational. It is their job" Different oath for officers; I didn't know that
www.thebulwark.com/p/what-ameri... Clarifying duties (plural) of military personnel toward unlawful orders. "Officers are duty-bound to refuse an unlawful order. It is not optional. It is not situational. It is their job" Different oath for officers; I didn't know that
What Americans Should Understand About the Military Disobeying Illegal Orders
And why it matters there are two military oaths.
www.thebulwark.com
November 21, 2025 at 6:30 PM
By @markhertling.bsky.social:
www.thebulwark.com/p/what-ameri... Clarifying duties (plural) of military personnel toward unlawful orders. "Officers are duty-bound to refuse an unlawful order. It is not optional. It is not situational. It is their job" Different oath for officers; I didn't know that
www.thebulwark.com/p/what-ameri... Clarifying duties (plural) of military personnel toward unlawful orders. "Officers are duty-bound to refuse an unlawful order. It is not optional. It is not situational. It is their job" Different oath for officers; I didn't know that
This is one of the most internally contradictory lines I have ever seen in a supposedly authoritative piece. www.washingtonpost.com/opinions/202...
November 19, 2025 at 4:40 PM
This is one of the most internally contradictory lines I have ever seen in a supposedly authoritative piece. www.washingtonpost.com/opinions/202...
November 18, 2025 at 12:13 AM
November 16, 2025 at 3:00 PM
The key message. If tumor (somatic) testing reveals a variant in a cancer predisposition gene, our data suggests a 20% chance that it's present in the germline. Oncologists should test for it.
We demonstrated that testing was feasible and about 25% of recurrent tumors had variants in cancer predisposition genes of which 20% were germline. Rapid reflex germline testing of tumor results is warranted.
November 12, 2025 at 1:21 AM
The key message. If tumor (somatic) testing reveals a variant in a cancer predisposition gene, our data suggests a 20% chance that it's present in the germline. Oncologists should test for it.
Reposted by Steve Joffe
Happy to report that the results of germline testing as part of the National Cancer Institute/Children’s Oncology Group MATCH precision oncology trial was published. pubmed.ncbi.nlm.nih.gov/41166674/
Germline Cancer Predisposition Results From the National Cancer Institute-Children's Oncology Group Pediatric MATCH Trial - PubMed
Coordinated germline and tumor panel testing was feasible and revealed P/LP CPG variants in 6.3% of the Pediatric MATCH cohort. Tumor variant fraction, germline association of CPG with tumor type, and adult-oriented guidelines were not predictive of germline status, emphasizing the need for systemat …
pubmed.ncbi.nlm.nih.gov
November 11, 2025 at 9:11 PM
Happy to report that the results of germline testing as part of the National Cancer Institute/Children’s Oncology Group MATCH precision oncology trial was published. pubmed.ncbi.nlm.nih.gov/41166674/
If Whiskey can't have my wife, he'll make do with her shoe.
November 10, 2025 at 9:54 PM
If Whiskey can't have my wife, he'll make do with her shoe.
Reposted by Steve Joffe
Congrats to Dr. Harsha Thirumurthy on his latest running achievement! He ran the Tunnel Hill 50-mile race in Illinois. He finished in 5:38:27, setting a new American men’s record in his age group, and breaking the previous record which had stood for a quarter century! @hthirumurthy.bsky.social
November 10, 2025 at 5:27 PM
Congrats to Dr. Harsha Thirumurthy on his latest running achievement! He ran the Tunnel Hill 50-mile race in Illinois. He finished in 5:38:27, setting a new American men’s record in his age group, and breaking the previous record which had stood for a quarter century! @hthirumurthy.bsky.social
Administration Live Updates: Trump Appeals Ruling That Orders Fast and Full SNAP Payments
www.nytimes.com
November 7, 2025 at 3:40 PM
Reposted by Steve Joffe
“If you sit there with someone who says Adolf Hitler was very, very cool, and that their mission is to combat and defeat global Jewry, and you say nothing, then you are a coward and you are complicit in that evil”. Cruz was right. Had he been feeling braver, he would not have stopped there.
November 4, 2025 at 3:02 PM
“If you sit there with someone who says Adolf Hitler was very, very cool, and that their mission is to combat and defeat global Jewry, and you say nothing, then you are a coward and you are complicit in that evil”. Cruz was right. Had he been feeling braver, he would not have stopped there.
Not just the lede...the whole article is wow.
Quite the lede on this Arthur Allen @kffhealthnews.org story on the medical freedom movement in Florida kffhealthnews.org/news/article...
"...several hundred gathered to honor state Surgeon General Joseph Ladapo, his wife, and an unlicensed Canadian radiologist who treats cancer with horse paste."
"...several hundred gathered to honor state Surgeon General Joseph Ladapo, his wife, and an unlicensed Canadian radiologist who treats cancer with horse paste."
At The Hollow in Florida, the ‘Medical Freedom’ Movement Finds Its Base Camp - KFF Health News
Florida’s surgeon general, spiritual healers, and Trump allies push their cures in a swampy outpost of anti-government absolutism and mystical belief.
kffhealthnews.org
November 3, 2025 at 7:56 PM
Not just the lede...the whole article is wow.
Odd name for an AI company.
October 30, 2025 at 6:18 PM
Odd name for an AI company.
Reposted by Steve Joffe
We're thrilled to announce we're recruiting for our #T32 #ELSI postdoc. Position starts Summer 2026. Please spread the word!
Learn more and apply: medicalethicshealthpolicy.med.upenn.edu/elsipostdoc
Learn more and apply: medicalethicshealthpolicy.med.upenn.edu/elsipostdoc
October 27, 2025 at 7:18 PM
We're thrilled to announce we're recruiting for our #T32 #ELSI postdoc. Position starts Summer 2026. Please spread the word!
Learn more and apply: medicalethicshealthpolicy.med.upenn.edu/elsipostdoc
Learn more and apply: medicalethicshealthpolicy.med.upenn.edu/elsipostdoc
Really appreciate this letter from Penn's President Jameson responding to the proposed "Compact for Academic Excellence in Higher Education."
penntoday.upenn.edu/announcement...
penntoday.upenn.edu/announcement...
Penn’s written response to the Compact for Academic Excellence | Penn Today
To the Penn Community,As I communicated to you on October 16, 2025, we sent a letter to the Department of Education in response to their request for limited, targeted feedback about the proposed Compa...
penntoday.upenn.edu
October 24, 2025 at 9:20 PM
Really appreciate this letter from Penn's President Jameson responding to the proposed "Compact for Academic Excellence in Higher Education."
penntoday.upenn.edu/announcement...
penntoday.upenn.edu/announcement...
Reposted by Steve Joffe
This is a fantastic, well-supported 3-year post-doc in our Division of Medical Ethics at Penn. Please share (and apply if interested!)
1/ Thrilled to announce that @pennmehp.bsky.social is recruiting for our NHGRI-funded postdoctoral fellowship in the ethical, legal, and social implications (ELSI) of genomics. Please share widely.
Details at medicalethicshealthpolicy.med.upenn.edu/elsipostdoc
Details at medicalethicshealthpolicy.med.upenn.edu/elsipostdoc
Penn Medical Ethics and Health Policy | ELSI Genomics Postdoctoral Training Program
About the Fellowship
The mission of the 3-year Penn Postdoctoral Training Program in the Ethical, Legal and Social Implications (ELSI) of Genetics and Genomics, supported by a training grant from...
medicalethicshealthpolicy.med.upenn.edu
October 23, 2025 at 9:45 AM
This is a fantastic, well-supported 3-year post-doc in our Division of Medical Ethics at Penn. Please share (and apply if interested!)
1/ Thrilled to announce that @pennmehp.bsky.social is recruiting for our NHGRI-funded postdoctoral fellowship in the ethical, legal, and social implications (ELSI) of genomics. Please share widely.
Details at medicalethicshealthpolicy.med.upenn.edu/elsipostdoc
Details at medicalethicshealthpolicy.med.upenn.edu/elsipostdoc
Penn Medical Ethics and Health Policy | ELSI Genomics Postdoctoral Training Program
About the Fellowship
The mission of the 3-year Penn Postdoctoral Training Program in the Ethical, Legal and Social Implications (ELSI) of Genetics and Genomics, supported by a training grant from...
medicalethicshealthpolicy.med.upenn.edu
October 23, 2025 at 12:31 AM
1/ Thrilled to announce that @pennmehp.bsky.social is recruiting for our NHGRI-funded postdoctoral fellowship in the ethical, legal, and social implications (ELSI) of genomics. Please share widely.
Details at medicalethicshealthpolicy.med.upenn.edu/elsipostdoc
Details at medicalethicshealthpolicy.med.upenn.edu/elsipostdoc
Reposted by Steve Joffe
A new @jama.com Insights article by LDI Fellows Kyra O’Brien, Emily Largent, and Jason Karlawish advises clinicians on how to communicate a diagnosis of MCI or dementia—emphasizing triadic communication, personalized content, and emotional support. http://doi.org/10.1001/jama.2025.13006
Communicating a Diagnosis of Mild Cognitive Impairment or Dementia
This JAMA Insights explores strategies for effectively communicating a diagnosis of mild cognitive impairment or dementia to patients and their care partners.
doi.org
October 22, 2025 at 4:25 PM
A new @jama.com Insights article by LDI Fellows Kyra O’Brien, Emily Largent, and Jason Karlawish advises clinicians on how to communicate a diagnosis of MCI or dementia—emphasizing triadic communication, personalized content, and emotional support. http://doi.org/10.1001/jama.2025.13006
Congratulations Stacie! So well deserved.
Absolutely thrilled to be a member of the National Academy of Medicine! Lifetime career achievement unlocked! Cannot thank my persistent nominators enough for this honor. Congratulations to the new cohort - it is so fun to see so many deserving people be recognized!
nam.edu/news-and-ins...
nam.edu/news-and-ins...
National Academy of Medicine Elects 100 New Members - NAM
WASHINGTON — The National Academy of Medicine (NAM) today announced the election of 90 regular members and 10 international members during its annual meeting.
nam.edu
October 20, 2025 at 6:42 PM
Congratulations Stacie! So well deserved.
Reposted by Steve Joffe
Scrolling all the pics and wondering: was it just an absolutely beautiful day in every corner of the country?
October 18, 2025 at 11:11 PM
Scrolling all the pics and wondering: was it just an absolutely beautiful day in every corner of the country?
Reposted by Steve Joffe
Penn declines to sign the compact.
Way to go!
Way to go!
October 16, 2025 at 5:09 PM
Penn declines to sign the compact.
Way to go!
Way to go!
Reposted by Steve Joffe
Northwest Chicago Suburb: ICE Agents Rip 15-Year-Old Girl from Car, Slam Her to Ground She Screams “I’m 15!” as Man Kneels on Her Neck
October 11, 2025 at 7:16 PM
Northwest Chicago Suburb: ICE Agents Rip 15-Year-Old Girl from Car, Slam Her to Ground She Screams “I’m 15!” as Man Kneels on Her Neck
Reposted by Steve Joffe
WaPo also gets it wrong: www.washingtonpost.com/education/20...
How about:
"MIT Rejects Trump Administration's Offer to Lose Everything"
How about:
"MIT Rejects Trump Administration's Offer to Lose Everything"
MIT rejects Trump administration deal for priority federal funding
MIT is one of the nine schools that were asked to agree to adopt conservative priorities and policies in exchange for funding perks.
www.washingtonpost.com
October 10, 2025 at 4:38 PM
WaPo also gets it wrong: www.washingtonpost.com/education/20...
How about:
"MIT Rejects Trump Administration's Offer to Lose Everything"
How about:
"MIT Rejects Trump Administration's Offer to Lose Everything"
Framing @nytimes.com is all wrong.
How about this: “Trump admin threatened 9 universities with withdrawal of critical things to which they’re legally entitled if they decline to align with the administration’s ideological agenda for higher ed.”
www.nytimes.com/2025/10/10/u...
How about this: “Trump admin threatened 9 universities with withdrawal of critical things to which they’re legally entitled if they decline to align with the administration’s ideological agenda for higher ed.”
www.nytimes.com/2025/10/10/u...
October 10, 2025 at 4:29 PM
Framing @nytimes.com is all wrong.
How about this: “Trump admin threatened 9 universities with withdrawal of critical things to which they’re legally entitled if they decline to align with the administration’s ideological agenda for higher ed.”
www.nytimes.com/2025/10/10/u...
How about this: “Trump admin threatened 9 universities with withdrawal of critical things to which they’re legally entitled if they decline to align with the administration’s ideological agenda for higher ed.”
www.nytimes.com/2025/10/10/u...