stephanripke.bsky.social
@stephanripke.bsky.social
Reposted
New study from the @pgcgenetics.bsky.social:

Multi-ancestry GWAS of MDD in over half a million cases and 4 million controls.

www.cell.com/cell/fulltex...
Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies
Trans-ancestry GWAS of major depression identifies 697 genetic variants and 308 genes, implicating neural and molecular mechanisms and drug repurposing opportunities.
www.cell.com
January 14, 2025 at 4:10 PM
Reposted
Happy to see this finally online: we investigated the genetic association signal of Borderline Personality Disorder in a GWAS meta-analysis with >12,000 cases. We identified 6 risk loci, and investigated shared genetic risk using genetic correlations and PheWAS
www.medrxiv.org/content/10.1...
Genome-wide association study of borderline personality disorder identifies six loci and highlights shared risk with mental and somatic disorders
Environmental and genetic risk factors contribute to the development of borderline personality disorder (BPD). We conducted the largest GWAS of BPD to date, meta-analyzing data from 12,339 cases and 1...
www.medrxiv.org
November 15, 2024 at 7:56 PM
Reposted
Thanks for the valued colleague award @pgcgenetics.bsky.social, which traveled all the way from Singapore to Berlin!
December 3, 2024 at 1:10 PM