Stephanie Wankowicz
@stephanieaw.bsky.social
Computational Structural Biologist
Assistant Professor @VanderbiltMPB
wankowiczlab.com
(she/her)
Past: UCSF, Dana-Farber, Broad Institute, UMass Amherst
Assistant Professor @VanderbiltMPB
wankowiczlab.com
(she/her)
Past: UCSF, Dana-Farber, Broad Institute, UMass Amherst
Runner wedding bliss!
September 27, 2025 at 8:11 PM
Runner wedding bliss!
I really didn’t think teams could get any worse.
May 18, 2025 at 11:39 PM
I really didn’t think teams could get any worse.
@vanallenlab.bsky.social 10 year reunion with over 50 people and dinner with part of cohort one. I miss doing science with these folks. ❤️
May 17, 2025 at 2:24 PM
@vanallenlab.bsky.social 10 year reunion with over 50 people and dinner with part of cohort one. I miss doing science with these folks. ❤️
London, you know how to throw a party.
April 28, 2025 at 11:23 PM
London, you know how to throw a party.
Nashville @standupforscience.bsky.social
March 7, 2025 at 7:42 PM
Nashville @standupforscience.bsky.social
Our lab’s guide from Light Hall to MRB3. I hope others in @vubasicsciences.bsky.social can appreciate!
February 27, 2025 at 11:48 PM
Our lab’s guide from Light Hall to MRB3. I hope others in @vubasicsciences.bsky.social can appreciate!
Coot & pizza party!
January 23, 2025 at 11:15 PM
Coot & pizza party!
I love this, but I am seeing examples where the widget says there are comments, but when I click on the comments there are none there.
January 21, 2025 at 7:14 PM
I love this, but I am seeing examples where the widget says there are comments, but when I click on the comments there are none there.
This seems to be due to more careful manual modeling as detected by more alternative conformations placed in binding sites and rotamer outliers identified in binding sites as having better density support.
December 16, 2024 at 3:14 PM
This seems to be due to more careful manual modeling as detected by more alternative conformations placed in binding sites and rotamer outliers identified in binding sites as having better density support.
Looking at PDBRedo structural models, we observed that binding site residues have improved fit to the underlying data based on multiple real space metrics, including real space R-values, RSCC, and EDIAm.
December 16, 2024 at 3:14 PM
Looking at PDBRedo structural models, we observed that binding site residues have improved fit to the underlying data based on multiple real space metrics, including real space R-values, RSCC, and EDIAm.
I led the journal club course for the first-year quantitative graduate students this semester. We spent the semester dissecting papers and discussing how to give constructive feedback. Their final project was to review a preprint, and they crushed it! wankowiczlab.com/reviews/
December 13, 2024 at 6:15 PM
I led the journal club course for the first-year quantitative graduate students this semester. We spent the semester dissecting papers and discussing how to give constructive feedback. Their final project was to review a preprint, and they crushed it! wankowiczlab.com/reviews/
Peak hospital building directions.
December 5, 2024 at 6:08 PM
Peak hospital building directions.
Go UMass!!! Bringing back good (and stressful) memories of organizing the first UMMB trip to Macy’s 12 years ago! 🤯
November 28, 2024 at 6:26 PM
Go UMass!!! Bringing back good (and stressful) memories of organizing the first UMMB trip to Macy’s 12 years ago! 🤯
We also proposed to allow both conformational and compositional information to be nested to capture more detailed information about heterogeneity.
October 30, 2023 at 4:51 PM
We also proposed to allow both conformational and compositional information to be nested to capture more detailed information about heterogeneity.
We envision capturing conformational (differing in conformation) and compositional (differing in chemical entities) information in separate data items, deconvolving each of these important entities.
October 30, 2023 at 4:51 PM
We envision capturing conformational (differing in conformation) and compositional (differing in chemical entities) information in separate data items, deconvolving each of these important entities.
We also observe evidence that conformational change and conformational entropy are intertwined, with conformational entropy often assisting in conformational changes from being made.
October 4, 2023 at 6:19 PM
We also observe evidence that conformational change and conformational entropy are intertwined, with conformational entropy often assisting in conformational changes from being made.
Protein folding reduces many conformational degrees of freedom, resulting in a significant entropic penalty. However, residual conformational entropy persists in the protein's native state as it fluctuates between thermally accessible conformations. chemrxiv.org/engage/chemr...
October 4, 2023 at 6:14 PM
Protein folding reduces many conformational degrees of freedom, resulting in a significant entropic penalty. However, residual conformational entropy persists in the protein's native state as it fluctuates between thermally accessible conformations. chemrxiv.org/engage/chemr...