Stephanie Wankowicz
@stephanieaw.bsky.social
Computational Structural Biologist
Assistant Professor @VanderbiltMPB
wankowiczlab.com
(she/her)
Past: UCSF, Dana-Farber, Broad Institute, UMass Amherst
Assistant Professor @VanderbiltMPB
wankowiczlab.com
(she/her)
Past: UCSF, Dana-Farber, Broad Institute, UMass Amherst
Reposted by Stephanie Wankowicz
Reposted by Stephanie Wankowicz
Announcing cryo-EM heterogeneity challenge #2, now dubbed the 2025 Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms (CAHRA)! Join us for a webinar next Friday (Nov 14th) to learn more. Datasets already posted here: heterogeneity.notion.site/challenge #cryoem
CAHRA 2025: Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms
A community-wide data processing challenge for cryo-electron microscopy.
heterogeneity.notion.site
November 7, 2025 at 10:45 PM
Announcing cryo-EM heterogeneity challenge #2, now dubbed the 2025 Community-Wide Assessment of Cryo-EM Heterogeneous Reconstruction Algorithms (CAHRA)! Join us for a webinar next Friday (Nov 14th) to learn more. Datasets already posted here: heterogeneity.notion.site/challenge #cryoem
❤️
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
November 5, 2025 at 11:52 PM
❤️
Reposted by Stephanie Wankowicz
Zara Weinberg passed away earlier this week. She joined my lab earlier this year when her postdoc lab formally closed.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
October 31, 2025 at 1:18 PM
Zara Weinberg passed away earlier this week. She joined my lab earlier this year when her postdoc lab formally closed.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.
Can confirm.
www.wsj.com/lifestyle/si...
www.wsj.com/lifestyle/si...
The Numbers Six and Seven Are Making Life Hell for Math Teachers
‘Six seven’ sends teens into a frenzy that schools have been powerless to stop. ‘It’s like throwing catnip at cats.’
www.wsj.com
October 29, 2025 at 11:04 PM
Can confirm.
www.wsj.com/lifestyle/si...
www.wsj.com/lifestyle/si...
Reposted by Stephanie Wankowicz
"It's past time to recognize that university administrators aren't going to lead the way out of this, [setting] the stage for leadership... from faculty, staff, & students, [where] most if not all progress in higher ed over the past 100 yrs has occurred."
www.science.org/doi/10.1126/...
#AcademicSky
www.science.org/doi/10.1126/...
#AcademicSky
Higher education fails at collective action
In the latest development in the ongoing combat between universities in the United States and the Trump administration, the Department of Education has presented them with what it calls a “compact.” I...
www.science.org
October 27, 2025 at 7:14 PM
"It's past time to recognize that university administrators aren't going to lead the way out of this, [setting] the stage for leadership... from faculty, staff, & students, [where] most if not all progress in higher ed over the past 100 yrs has occurred."
www.science.org/doi/10.1126/...
#AcademicSky
www.science.org/doi/10.1126/...
#AcademicSky
Reposted by Stephanie Wankowicz
🚨PhD opportunity at the intersection of computation & biology! 🖥️🧬🧪
Ready to tackle complex biological problems with cutting-edge tools? The BMI PhD program @UCSF trains future leaders in comp bio, bioinformatics, & data science.
📢 Info session: 11/6 @ 1 PM PT
bmi.ucsf.edu/admissions
Learn more👇
Ready to tackle complex biological problems with cutting-edge tools? The BMI PhD program @UCSF trains future leaders in comp bio, bioinformatics, & data science.
📢 Info session: 11/6 @ 1 PM PT
bmi.ucsf.edu/admissions
Learn more👇
October 24, 2025 at 6:26 PM
🚨PhD opportunity at the intersection of computation & biology! 🖥️🧬🧪
Ready to tackle complex biological problems with cutting-edge tools? The BMI PhD program @UCSF trains future leaders in comp bio, bioinformatics, & data science.
📢 Info session: 11/6 @ 1 PM PT
bmi.ucsf.edu/admissions
Learn more👇
Ready to tackle complex biological problems with cutting-edge tools? The BMI PhD program @UCSF trains future leaders in comp bio, bioinformatics, & data science.
📢 Info session: 11/6 @ 1 PM PT
bmi.ucsf.edu/admissions
Learn more👇
Reposted by Stephanie Wankowicz
It was such an honor for me to work with awesome colleagues Needhi Bhalla and JoAnn Trejo on this important piece 👇
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
Scaling back DEI programmes and the loss of scientific talent
Nature Cell Biology - Programmes that support diversity, equity and inclusion (DEI) in science are under attack in the USA. Data indicate that diversity in the scientific workforce increases...
www.nature.com
October 23, 2025 at 6:42 PM
It was such an honor for me to work with awesome colleagues Needhi Bhalla and JoAnn Trejo on this important piece 👇
Reposted by Stephanie Wankowicz
1. We ( @jbakcoleman.bsky.social, @cailinmeister.bsky.social, @jevinwest.bsky.social, and I) have a new preprint up on the arXiv.
There we explore how social media companies and other online information technology firms are able to manipulate scientific research about the effects of their products.
There we explore how social media companies and other online information technology firms are able to manipulate scientific research about the effects of their products.
October 24, 2025 at 12:47 AM
1. We ( @jbakcoleman.bsky.social, @cailinmeister.bsky.social, @jevinwest.bsky.social, and I) have a new preprint up on the arXiv.
There we explore how social media companies and other online information technology firms are able to manipulate scientific research about the effects of their products.
There we explore how social media companies and other online information technology firms are able to manipulate scientific research about the effects of their products.
Reposted by Stephanie Wankowicz
**Job Alert** Exciting postdoc position available: theoretical and experimental cryo-EM studies of flexible biomolecules. Competitive salary, collaborative environment at NYSBC and Flatiron Institute. Please share!! and contact: pcossio@flatironinstitute.org
October 22, 2025 at 2:55 PM
**Job Alert** Exciting postdoc position available: theoretical and experimental cryo-EM studies of flexible biomolecules. Competitive salary, collaborative environment at NYSBC and Flatiron Institute. Please share!! and contact: pcossio@flatironinstitute.org
TTPD #8 with @fraserlab.com: Open access, Clear science, Full hearts, Can’t lose!
We chat about the Compact for Academic Excellence in Higher Education, HHMI open access, the government shutdown, the BEAR, the Nobel Prizes, and The Life of a Showgirl! wankowiczlab.com/2025/10/23/T...
We chat about the Compact for Academic Excellence in Higher Education, HHMI open access, the government shutdown, the BEAR, the Nobel Prizes, and The Life of a Showgirl! wankowiczlab.com/2025/10/23/T...
The Tortured Proteins Department, Episode 8
This is the official web page for the Stephanie Wankowicz Lab at Vanderbilt University.
wankowiczlab.com
October 23, 2025 at 3:39 PM
TTPD #8 with @fraserlab.com: Open access, Clear science, Full hearts, Can’t lose!
We chat about the Compact for Academic Excellence in Higher Education, HHMI open access, the government shutdown, the BEAR, the Nobel Prizes, and The Life of a Showgirl! wankowiczlab.com/2025/10/23/T...
We chat about the Compact for Academic Excellence in Higher Education, HHMI open access, the government shutdown, the BEAR, the Nobel Prizes, and The Life of a Showgirl! wankowiczlab.com/2025/10/23/T...
Updated preprint on the roadmap to predicting macromolecular ensembles with @bonomimax.bsky.social! Four key issues:
1) Structural ensembles are defined inconsistently across disciplines.
2) No single experimental technique alone can fully capture structural ensembles
arxiv.org/abs/2505.01919
1) Structural ensembles are defined inconsistently across disciplines.
2) No single experimental technique alone can fully capture structural ensembles
arxiv.org/abs/2505.01919
October 23, 2025 at 2:24 PM
Updated preprint on the roadmap to predicting macromolecular ensembles with @bonomimax.bsky.social! Four key issues:
1) Structural ensembles are defined inconsistently across disciplines.
2) No single experimental technique alone can fully capture structural ensembles
arxiv.org/abs/2505.01919
1) Structural ensembles are defined inconsistently across disciplines.
2) No single experimental technique alone can fully capture structural ensembles
arxiv.org/abs/2505.01919
Reposted by Stephanie Wankowicz
🎓👏 Join us in honoring dean emeritus Larry Marnett, whose five decades of dedication to science, leadership, and mentorship was highlighted during a reunion of 70+ former trainees from around the globe.
Read more about this tribute 👉 medschool.vanderbilt.edu/basic-scienc...
Read more about this tribute 👉 medschool.vanderbilt.edu/basic-scienc...
From Lab to Legacy: Marnett’s Trainees Gather to Toast a Life in Science and Service
In a heartwarming tribute to a remarkable career, more than 70 of his former graduate students and postdoctoral scholars recently traveled from across the globe for a three-day festivity on Oct. 3–…
medschool.vanderbilt.edu
October 22, 2025 at 4:15 PM
🎓👏 Join us in honoring dean emeritus Larry Marnett, whose five decades of dedication to science, leadership, and mentorship was highlighted during a reunion of 70+ former trainees from around the globe.
Read more about this tribute 👉 medschool.vanderbilt.edu/basic-scienc...
Read more about this tribute 👉 medschool.vanderbilt.edu/basic-scienc...
Structural biology techniques capture an enormous amount of conformational heterogeneity, which is often lost during the transition from experimental data to deposited models, including how we encode this heterogeneity. @diffuseproject.bsky.social
October 21, 2025 at 4:30 PM
Structural biology techniques capture an enormous amount of conformational heterogeneity, which is often lost during the transition from experimental data to deposited models, including how we encode this heterogeneity. @diffuseproject.bsky.social
Reposted by Stephanie Wankowicz
I spend a lot of time talking to potential grantees about our open science policy. Some field notes here:
open.substack.com/pub/seemay/p...
open.substack.com/pub/seemay/p...
Why careerism can be bad for science training
Some field notes from scholarly publishing discussions with scientists
open.substack.com
October 21, 2025 at 3:52 PM
I spend a lot of time talking to potential grantees about our open science policy. Some field notes here:
open.substack.com/pub/seemay/p...
open.substack.com/pub/seemay/p...
Reposted by Stephanie Wankowicz
Nominations for the June Almeida award for Mid/Senior-Career Women in Cryo-EM are now open! Submit your nomination via this link www.biophysics.org/awards-fundi... by November 14th to recognize an exceptional woman in our community.
Subgroup Awards - The Biophysical Society
www.biophysics.org
October 16, 2025 at 7:08 PM
Nominations for the June Almeida award for Mid/Senior-Career Women in Cryo-EM are now open! Submit your nomination via this link www.biophysics.org/awards-fundi... by November 14th to recognize an exceptional woman in our community.
Reposted by Stephanie Wankowicz
A university that signs the “compact” is one that acknowledges its own inability to compete and succeed based talent and merit. It would signal insecurity and mediocrity to current and future students and faculty. Say no. Recruit the best people, protect their freedom and support their hard work.
October 18, 2025 at 12:05 AM
A university that signs the “compact” is one that acknowledges its own inability to compete and succeed based talent and merit. It would signal insecurity and mediocrity to current and future students and faculty. Say no. Recruit the best people, protect their freedom and support their hard work.
Reposted by Stephanie Wankowicz
A method called PIGEON-FEATHER can unambiguously determine residue-level energies of local unfolding from conventional HX-MS datasets
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Site-resolved energetic information from HX–MS experiments - Nature Chemical Biology
Hydrogen exchange–mass spectrometry (HX–MS) is used to qualitatively assess how perturbations such as mutations and ligand binding impact protein ensembles. However, in theory, HX–MS data contain the ...
www.nature.com
October 17, 2025 at 4:53 PM
A method called PIGEON-FEATHER can unambiguously determine residue-level energies of local unfolding from conventional HX-MS datasets
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Stephanie Wankowicz
No words
May 30, 2025 at 12:23 PM
No words
Reposted by Stephanie Wankowicz
Vanderbilt AAUP press release about the Vanderbilt Faculty Senate voting overwhelmingly to adopt a resolution opposing the President's proposed Compact for Academic Excellence in Higher Education as an unconstitutional & illegal infringement on rights & freedoms.
vanderbiltaaup.org/2025/10/09/v...
vanderbiltaaup.org/2025/10/09/v...
Vanderbilt Faculty Senate Votes Overwhelmingly to Oppose Trump Loyalty Oath
The Vanderbilt Faculty Senate overwhelmingly passed a resolution opposing President Trump’s proposed “Compact for Excellence in Higher Education.” The resolution, citing concerns …
vanderbiltaaup.org
October 10, 2025 at 8:54 PM
Vanderbilt AAUP press release about the Vanderbilt Faculty Senate voting overwhelmingly to adopt a resolution opposing the President's proposed Compact for Academic Excellence in Higher Education as an unconstitutional & illegal infringement on rights & freedoms.
vanderbiltaaup.org/2025/10/09/v...
vanderbiltaaup.org/2025/10/09/v...
Reposted by Stephanie Wankowicz
Reposted by Stephanie Wankowicz
The Diffuse Project is looking for an amazing Project Manager to help us achieve our goal of unlocking protein dynamics! Are you a scientist who naturally loves organization, coordination, problem solving and working with a diverse team of scientists & engineers?
October 7, 2025 at 2:11 AM
The Diffuse Project is looking for an amazing Project Manager to help us achieve our goal of unlocking protein dynamics! Are you a scientist who naturally loves organization, coordination, problem solving and working with a diverse team of scientists & engineers?
Reposted by Stephanie Wankowicz
TTPD #7 with @fraserlab.com.
We chatted about the recent meetings, news, preprint engagement notifications, and the point of rotations.
wankowiczlab.com/2025/09/27/T...
Spotify: open.spotify.com/episode/0JCB...
We chatted about the recent meetings, news, preprint engagement notifications, and the point of rotations.
wankowiczlab.com/2025/09/27/T...
Spotify: open.spotify.com/episode/0JCB...
The Tortured Proteins Department, Episode 7
This is the official web page for the Stephanie Wankowicz Lab at Vanderbilt University.
wankowiczlab.com
September 27, 2025 at 8:00 PM
TTPD #7 with @fraserlab.com.
We chatted about the recent meetings, news, preprint engagement notifications, and the point of rotations.
wankowiczlab.com/2025/09/27/T...
Spotify: open.spotify.com/episode/0JCB...
We chatted about the recent meetings, news, preprint engagement notifications, and the point of rotations.
wankowiczlab.com/2025/09/27/T...
Spotify: open.spotify.com/episode/0JCB...