StayCurious Metabolism
@staycuriousmetabolism.skystack.xyz
We will cultivate nuance and curiosity for all things metabolism. Make Metabolic Health Mainstream!
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This is an automated Substack Account of https://staycuriousmetabolism.substack.com
Discover more/Create at: @skystack.xyz
The Biomarker That Ate Cardiology • LDL cholesterol (LDL-C) has been elevated to a position of dominance in cardiovascular medicine that is not justified by its relative contribution to risk. That imbalance doesn’t just distort...
The Biomarker That Ate Cardiology
LDL cholesterol (LDL-C) has been elevated to a position of dominance in cardiovascular medicine that is not justified by its relative contribution to risk. That imbalance doesn’t just distort...
staycuriousmetabolism.substack.com
December 28, 2025 at 2:44 PM
The Biomarker That Ate Cardiology • LDL cholesterol (LDL-C) has been elevated to a position of dominance in cardiovascular medicine that is not justified by its relative contribution to risk. That imbalance doesn’t just distort...
Young Blood Can Extend Lifespan by 12%. Here's the Mechanism. • Tiny bubbles in your blood might help turn back the clock on aging. Scientists are learning how they boost energy, brain health, and more.
Young Blood Can Extend Lifespan by 12%. Here's the Mechanism.
Tiny bubbles in your blood might help turn back the clock on aging. Scientists are learning how they boost energy, brain health, and more.
staycuriousmetabolism.substack.com
December 27, 2025 at 2:53 PM
Young Blood Can Extend Lifespan by 12%. Here's the Mechanism. • Tiny bubbles in your blood might help turn back the clock on aging. Scientists are learning how they boost energy, brain health, and more.
Poop Calories & Burn Fat: A Guide for the Metabolically Curious • A practical guide to science-backed diet and lifestyle strategies designed to safely boost your metabolism.
Poop Calories & Burn Fat: A Guide for the Metabolically Curious
A practical guide to science-backed diet and lifestyle strategies designed to safely boost your metabolism.
staycuriousmetabolism.substack.com
December 23, 2025 at 2:53 PM
Poop Calories & Burn Fat: A Guide for the Metabolically Curious • A practical guide to science-backed diet and lifestyle strategies designed to safely boost your metabolism.
Nattokinase: The Heart Health Supplement on Everyone’s Tongue • When it comes to cardiovascular health, few supplements have sparked as much public interest — or confusion — as nattokinase. Let's unpack...
Nattokinase: The Heart Health Supplement on Everyone’s Tongue
When it comes to cardiovascular health, few supplements have sparked as much public interest — or confusion — as nattokinase. Let's unpack...
staycuriousmetabolism.substack.com
December 21, 2025 at 2:50 PM
Nattokinase: The Heart Health Supplement on Everyone’s Tongue • When it comes to cardiovascular health, few supplements have sparked as much public interest — or confusion — as nattokinase. Let's unpack...
High-Fat Cheese Lowers Dementia Risk—Too Gouda to Be True? • A brand-new paper in Neurology that followed people for 25 years and found that higher intake of high-fat cheese, but not low-fat cheese, was associated with a reduced risk of dementia. But...
High-Fat Cheese Lowers Dementia Risk—Too Gouda to Be True?
A brand-new paper in Neurology that followed people for 25 years and found that higher intake of high-fat cheese, but not low-fat cheese, was associated with a reduced risk of dementia. But...
staycuriousmetabolism.substack.com
December 20, 2025 at 2:47 PM
High-Fat Cheese Lowers Dementia Risk—Too Gouda to Be True? • A brand-new paper in Neurology that followed people for 25 years and found that higher intake of high-fat cheese, but not low-fat cheese, was associated with a reduced risk of dementia. But...
Inside My Supplement Stack: What I Take and Why • A transparent look at the supplements I use for muscle, brain, gut, and sleep health — and the personal reasoning behind each choice.
Inside My Supplement Stack: What I Take and Why
A transparent look at the supplements I use for muscle, brain, gut, and sleep health — and the personal reasoning behind each choice.
staycuriousmetabolism.substack.com
December 18, 2025 at 2:49 PM
Inside My Supplement Stack: What I Take and Why • A transparent look at the supplements I use for muscle, brain, gut, and sleep health — and the personal reasoning behind each choice.
This Drug Raises LDL Cholesterol—And Saves Lives • What if I told you there’s a medication that raises LDL “bad” cholesterol—yet actually saves lives, including from cardiovascular disease?
This Drug Raises LDL Cholesterol—And Saves Lives
What if I told you there’s a medication that raises LDL “bad” cholesterol—yet actually saves lives, including from cardiovascular disease?
staycuriousmetabolism.substack.com
December 16, 2025 at 2:50 PM
This Drug Raises LDL Cholesterol—And Saves Lives • What if I told you there’s a medication that raises LDL “bad” cholesterol—yet actually saves lives, including from cardiovascular disease?
A Doctor Texted Me: “I’m Stopping My Statin”—Here’s Why • New study finds statin use is associated with a decline in muscle function and mass over time. Let's discuss what the data reveal and what questions remain...
A Doctor Texted Me: “I’m Stopping My Statin”—Here’s Why
New study finds statin use is associated with a decline in muscle function and mass over time. Let's discuss what the data reveal and what questions remain...
staycuriousmetabolism.substack.com
December 13, 2025 at 2:54 PM
A Doctor Texted Me: “I’m Stopping My Statin”—Here’s Why • New study finds statin use is associated with a decline in muscle function and mass over time. Let's discuss what the data reveal and what questions remain...
How Sardines Accidentally Supercharged my Metabolism • I recently did a radical dietary experiment — and something totally unexpected happened...
How Sardines Accidentally Supercharged my Metabolism
I recently did a radical dietary experiment — and something totally unexpected happened...
staycuriousmetabolism.substack.com
December 11, 2025 at 2:51 PM
How Sardines Accidentally Supercharged my Metabolism • I recently did a radical dietary experiment — and something totally unexpected happened...
Omega-3 Supplements Don't Work - With One Exception • Paradox: Eating more dietary omega-3s is associated with superior cognitive longevity. But there is not a strong signal for the benefits of supplemental omega-3s. Why? And what should you do?
Omega-3 Supplements Don't Work - With One Exception
Paradox: Eating more dietary omega-3s is associated with superior cognitive longevity. But there is not a strong signal for the benefits of supplemental omega-3s. Why? And what should you do?
staycuriousmetabolism.substack.com
December 9, 2025 at 5:47 PM
Omega-3 Supplements Don't Work - With One Exception • Paradox: Eating more dietary omega-3s is associated with superior cognitive longevity. But there is not a strong signal for the benefits of supplemental omega-3s. Why? And what should you do?
How Metabolic Disease Feeds Emotional Eating • Metabolic disease shape mood through the gut. Let's unpack how a microbiome-made molecule, ImP, alters stress coping & fuels emotional eating.
How Metabolic Disease Feeds Emotional Eating
Metabolic disease shape mood through the gut. Let's unpack how a microbiome-made molecule, ImP, alters stress coping & fuels emotional eating.
staycuriousmetabolism.substack.com
December 7, 2025 at 2:52 PM
How Metabolic Disease Feeds Emotional Eating • Metabolic disease shape mood through the gut. Let's unpack how a microbiome-made molecule, ImP, alters stress coping & fuels emotional eating.
Cholesterol Is Dropping… But Is Your Cardiovascular Risk? • In this letter, we examine not one but three meta-analyses of randomized controlled trials to explore a provocative question: Is modern medicine confused about how statins work?
Cholesterol Is Dropping… But Is Your Cardiovascular Risk?
In this letter, we examine not one but three meta-analyses of randomized controlled trials to explore a provocative question: Is modern medicine confused about how statins work?
staycuriousmetabolism.substack.com
December 6, 2025 at 2:55 PM
Cholesterol Is Dropping… But Is Your Cardiovascular Risk? • In this letter, we examine not one but three meta-analyses of randomized controlled trials to explore a provocative question: Is modern medicine confused about how statins work?
A Keto Diet Cured my Inflammatory Bowel Disease. What Does the Science Say... • A look into groundbreaking data from Cell, combined with personal insights, showing how a well-formulated ketogenic diet may hold the key to healing intestinal inflammation at its root.
A Keto Diet Cured my Inflammatory Bowel Disease. What Does the Science Say...
A look into groundbreaking data from Cell, combined with personal insights, showing how a well-formulated ketogenic diet may hold the key to healing intestinal inflammation at its root.
staycuriousmetabolism.substack.com
December 4, 2025 at 2:54 PM
A Keto Diet Cured my Inflammatory Bowel Disease. What Does the Science Say... • A look into groundbreaking data from Cell, combined with personal insights, showing how a well-formulated ketogenic diet may hold the key to healing intestinal inflammation at its root.
Saint Dr Nick's Holiday Gift Guide • It’s that season, so I’m going to do something a little out of character. Instead of giving you a detailed breakdown of the latest Cell or Nature paper, I’m giving you a holiday gift guide.
Saint Dr Nick's Holiday Gift Guide
It’s that season, so I’m going to do something a little out of character. Instead of giving you a detailed breakdown of the latest Cell or Nature paper, I’m giving you a holiday gift guide.
staycuriousmetabolism.substack.com
December 3, 2025 at 2:53 PM
Saint Dr Nick's Holiday Gift Guide • It’s that season, so I’m going to do something a little out of character. Instead of giving you a detailed breakdown of the latest Cell or Nature paper, I’m giving you a holiday gift guide.
Stop Saying “Eat More Fiber.” Start Asking These Three Questions Instead. • Fiber is a complex group of compounds with radically different effects across individuals. In this letter, we’ll break down one of the most elegant fiber studies published in recent years.
Stop Saying “Eat More Fiber.” Start Asking These Three Questions Instead.
Fiber is a complex group of compounds with radically different effects across individuals. In this letter, we’ll break down one of the most elegant fiber studies published in recent years.
staycuriousmetabolism.substack.com
December 2, 2025 at 2:53 PM
Stop Saying “Eat More Fiber.” Start Asking These Three Questions Instead. • Fiber is a complex group of compounds with radically different effects across individuals. In this letter, we’ll break down one of the most elegant fiber studies published in recent years.
This Study Changed How I See Junk Food Forever • Because a junk food binge doesn’t just hit your waistline — it leaves a metabolic scar, and in the last place you’d ever want one. Your brain.
This Study Changed How I See Junk Food Forever
Because a junk food binge doesn’t just hit your waistline — it leaves a metabolic scar, and in the last place you’d ever want one. Your brain.
staycuriousmetabolism.substack.com
November 29, 2025 at 2:46 PM
This Study Changed How I See Junk Food Forever • Because a junk food binge doesn’t just hit your waistline — it leaves a metabolic scar, and in the last place you’d ever want one. Your brain.
How Illness Broke Me — and Curiosity Rebuilt Me • A personal journey through misdiagnosis, resilience, and discovery — and how science, curiosity, and community helped me reclaim my health when medicine didn’t have the answers.
How Illness Broke Me — and Curiosity Rebuilt Me
A personal journey through misdiagnosis, resilience, and discovery — and how science, curiosity, and community helped me reclaim my health when medicine didn’t have the answers.
staycuriousmetabolism.substack.com
November 27, 2025 at 2:52 PM
How Illness Broke Me — and Curiosity Rebuilt Me • A personal journey through misdiagnosis, resilience, and discovery — and how science, curiosity, and community helped me reclaim my health when medicine didn’t have the answers.
How Berberine Lowers Cholesterol: Blew My Mind! • This mind-blowing study revealed how berberine lowers LDL cholesterol through a mechanism that’s completely different from that underlying statins or other drugs.
How Berberine Lowers Cholesterol: Blew My Mind!
This mind-blowing study revealed how berberine lowers LDL cholesterol through a mechanism that’s completely different from that underlying statins or other drugs.
staycuriousmetabolism.substack.com
November 25, 2025 at 2:53 PM
How Berberine Lowers Cholesterol: Blew My Mind! • This mind-blowing study revealed how berberine lowers LDL cholesterol through a mechanism that’s completely different from that underlying statins or other drugs.
Microplastics in My Heart: It’s Worse Than I Thought • Plastic is poisoning your heart and increasing your risk of heart attack, stroke and death by as much as 350%. Here's what you can do about it.
Microplastics in My Heart: It’s Worse Than I Thought
Plastic is poisoning your heart and increasing your risk of heart attack, stroke and death by as much as 350%. Here's what you can do about it.
staycuriousmetabolism.substack.com
November 24, 2025 at 12:30 PM
Microplastics in My Heart: It’s Worse Than I Thought • Plastic is poisoning your heart and increasing your risk of heart attack, stroke and death by as much as 350%. Here's what you can do about it.
One Tiny Edit, One Giant Leap for Brain Health • This Alzheimer’s study gave me goosebumps. In this deep dive, I unpack the science, the hope, and what it could mean for the future of brain health.
One Tiny Edit, One Giant Leap for Brain Health
This Alzheimer’s study gave me goosebumps. In this deep dive, I unpack the science, the hope, and what it could mean for the future of brain health.
staycuriousmetabolism.substack.com
November 24, 2025 at 12:30 PM
One Tiny Edit, One Giant Leap for Brain Health • This Alzheimer’s study gave me goosebumps. In this deep dive, I unpack the science, the hope, and what it could mean for the future of brain health.
A Breakthrough in Obesity Biology: The Brain Signal We Finally Understand • New research reveals that fat cells send “letters” to the brain that control hunger and metabolism. In obesity, the message becomes corrupted. But scientists may have finally cracked the code.
A Breakthrough in Obesity Biology: The Brain Signal We Finally Understand
New research reveals that fat cells send “letters” to the brain that control hunger and metabolism. In obesity, the message becomes corrupted. But scientists may have finally cracked the code.
staycuriousmetabolism.substack.com
November 24, 2025 at 12:30 PM
A Breakthrough in Obesity Biology: The Brain Signal We Finally Understand • New research reveals that fat cells send “letters” to the brain that control hunger and metabolism. In obesity, the message becomes corrupted. But scientists may have finally cracked the code.
The Great Gut Reset: A 4-Phase Framework to Rebuild a Resilient Microbiome • Can you hit "reset" on your microbiome? In this newsletter, I’m going to explore what that reset might look like.
The Great Gut Reset: A 4-Phase Framework to Rebuild a Resilient Microbiome
Can you hit "reset" on your microbiome? In this newsletter, I’m going to explore what that reset might look like.
staycuriousmetabolism.substack.com
November 24, 2025 at 12:30 PM
The Great Gut Reset: A 4-Phase Framework to Rebuild a Resilient Microbiome • Can you hit "reset" on your microbiome? In this newsletter, I’m going to explore what that reset might look like.
Sardine Fasting. The Ultimate Health Hack • In this letter, we explore the mechanistic rationale behind sardine fasting and then move into the how-to: a practical, modifiable protocol you can tailor tailor to your goals.
Sardine Fasting. The Ultimate Health Hack
In this letter, we explore the mechanistic rationale behind sardine fasting and then move into the how-to: a practical, modifiable protocol you can tailor tailor to your goals.
staycuriousmetabolism.substack.com
November 24, 2025 at 12:30 PM
Sardine Fasting. The Ultimate Health Hack • In this letter, we explore the mechanistic rationale behind sardine fasting and then move into the how-to: a practical, modifiable protocol you can tailor tailor to your goals.
Better Than Statins? The Truth About the New Cholesterol Drug • Coverage of a new PCSK9 trial makes bold claims about prevention and risk reduction. But how well do they hold up to scrutiny—and what nuances do you need to know? Let’s dig in.
Better Than Statins? The Truth About the New Cholesterol Drug
Coverage of a new PCSK9 trial makes bold claims about prevention and risk reduction. But how well do they hold up to scrutiny—and what nuances do you need to know? Let’s dig in.
staycuriousmetabolism.substack.com
November 24, 2025 at 12:30 PM
Better Than Statins? The Truth About the New Cholesterol Drug • Coverage of a new PCSK9 trial makes bold claims about prevention and risk reduction. But how well do they hold up to scrutiny—and what nuances do you need to know? Let’s dig in.
The Fasting Side Effect No One Talks About • Research reveals a surprising link between fat-burning, stem cells, and hair loss—and what you can do about it.
The Fasting Side Effect No One Talks About
Research reveals a surprising link between fat-burning, stem cells, and hair loss—and what you can do about it.
staycuriousmetabolism.substack.com
November 24, 2025 at 12:30 PM
The Fasting Side Effect No One Talks About • Research reveals a surprising link between fat-burning, stem cells, and hair loss—and what you can do about it.