Spenny
@spenny.bsky.social
PhD in Medical Genetics / Genomics / Paediatric Cancer Research / Drug Safety / 2018 Norwood Fair 2nd place chocolate chip cookies
Pinned
Spenny
@spenny.bsky.social
· Mar 24
Amino Acid Stress Response Genes Contribute to a 25‐Fold Increased Risk of L‐Asparaginase–Induced Hypersensitivity
Background L-asparaginase is essential in treating pediatric acute lymphoblastic leukemia (ALL) but is limited by hypersensitivity reactions in up to 70% of patients, leading to severe, dose-limitin...
onlinelibrary.wiley.com
Excited to share our Canada-wide study in Pediatric Blood & Cancer identifying genetic markers predicting severe hypersensitivity reactions to a vital drug in pediatric leukemia—moving closer to safer, personalized treatments. Let’s connect! #PrecisionMedicine #Pharmacogenomics #PediatricCancer
Excited to share our Canada-wide study in Pediatric Blood & Cancer identifying genetic markers predicting severe hypersensitivity reactions to a vital drug in pediatric leukemia—moving closer to safer, personalized treatments. Let’s connect! #PrecisionMedicine #Pharmacogenomics #PediatricCancer
Amino Acid Stress Response Genes Contribute to a 25‐Fold Increased Risk of L‐Asparaginase–Induced Hypersensitivity
Background L-asparaginase is essential in treating pediatric acute lymphoblastic leukemia (ALL) but is limited by hypersensitivity reactions in up to 70% of patients, leading to severe, dose-limitin...
onlinelibrary.wiley.com
March 24, 2025 at 9:20 PM
Excited to share our Canada-wide study in Pediatric Blood & Cancer identifying genetic markers predicting severe hypersensitivity reactions to a vital drug in pediatric leukemia—moving closer to safer, personalized treatments. Let’s connect! #PrecisionMedicine #Pharmacogenomics #PediatricCancer
I built an AI Agent called “2nd Reviewer” to automate systematic reviews.
Check it out and let me know what you think!
youtu.be/80W1ym5sYj4?...
Check it out and let me know what you think!
youtu.be/80W1ym5sYj4?...
Data Group: Nov 26 Generative AI & Data Science Workshop
YouTube video by E2i Theme
youtu.be
December 2, 2024 at 8:30 PM
I built an AI Agent called “2nd Reviewer” to automate systematic reviews.
Check it out and let me know what you think!
youtu.be/80W1ym5sYj4?...
Check it out and let me know what you think!
youtu.be/80W1ym5sYj4?...
Continuation of asparaginase is crucial for survival in pediatric ALL, yet allergies and pancreatitis often lead to its discontinuation. This study highlights the impact on outcomes and underscores the importance of strategies to maintain treatment: pmc.ncbi.nlm.nih.gov/articles/PMC...
November 19, 2024 at 7:51 PM
Continuation of asparaginase is crucial for survival in pediatric ALL, yet allergies and pancreatitis often lead to its discontinuation. This study highlights the impact on outcomes and underscores the importance of strategies to maintain treatment: pmc.ncbi.nlm.nih.gov/articles/PMC...
Anyone want to build a sequencer?
November 18, 2024 at 7:02 PM
Anyone want to build a sequencer?
Congratulations to my friend and colleague Khair on his latest publication which identified protective genetic variants for vincristine-induced peripheral neuropathy, a severely limiting drug reaction in childhood cancer www.nature.com/articles/s41...
Genomic variations associated with risk and protection against vincristine-induced peripheral neuropathy in pediatric cancer patients - npj Genomic Medicine
npj Genomic Medicine - Genomic variations associated with risk and protection against vincristine-induced peripheral neuropathy in pediatric cancer patients
www.nature.com
November 16, 2024 at 4:33 AM
Congratulations to my friend and colleague Khair on his latest publication which identified protective genetic variants for vincristine-induced peripheral neuropathy, a severely limiting drug reaction in childhood cancer www.nature.com/articles/s41...
Hey Bluesky! I’m Spenny, a PhD in Medical Genetics where my research focuses on the use of genomic profiles to earlier predict adverse drug outcomes in paediatric cancer patients🧬⚡️
Looking forward to building a great scientific community here - let’s connect! 🚀
Looking forward to building a great scientific community here - let’s connect! 🚀
November 16, 2024 at 4:07 AM
Hey Bluesky! I’m Spenny, a PhD in Medical Genetics where my research focuses on the use of genomic profiles to earlier predict adverse drug outcomes in paediatric cancer patients🧬⚡️
Looking forward to building a great scientific community here - let’s connect! 🚀
Looking forward to building a great scientific community here - let’s connect! 🚀