The Freeman Lab
@spencerfreeman.bsky.social
Reposted by The Freeman Lab
This work was done in tandem with cool work from the @spencerfreeman.bsky.social lab identifying novel regulators of PI3,5P2 in lysosomes
rupress.org/jcb/article-...
rupress.org/jcb/article-...
Sorting nexin 10 regulates lysosomal ionic homeostasis via ClC-7 by controlling PI(3,5)P2
Snx10 was found to determine the level of PI(3,5)P2 in (phago)lysosomes by controlling the supply of PI(3)P from upstream endocytic compartments. By regula
rupress.org
March 31, 2025 at 4:25 PM
This work was done in tandem with cool work from the @spencerfreeman.bsky.social lab identifying novel regulators of PI3,5P2 in lysosomes
rupress.org/jcb/article-...
rupress.org/jcb/article-...