Christian Speck
@speck-lab.bsky.social
Biochemist who uses interdisciplinary approaches to uncover molecular mechanisms in DNA replication. Professor at Imperial College London specklab.com
Blue-sky, I need your help. Is alphafold good in predicting protein-protein interactions involving beta sheets?
October 27, 2025 at 5:26 PM
Blue-sky, I need your help. Is alphafold good in predicting protein-protein interactions involving beta sheets?
Reposted by Christian Speck
A new study, published today in Nature, reveals the hidden benefits of weight loss on fat tissue.
A better understanding of how weight loss leads to health improvements at a molecular level could help inform the development of therapies for diseases such as type 2 diabetes in the future.
A better understanding of how weight loss leads to health improvements at a molecular level could help inform the development of therapies for diseases such as type 2 diabetes in the future.
Study reveals the hidden benefits of weight loss on fat tissue
Scientists from the MRC Laboratory of Medical Sciences (LMS) and Imperial College London have produced the first detailed characterisation of the changes that weight loss causes in human fat tissue by...
lms.mrc.ac.uk
July 9, 2025 at 3:19 PM
A new study, published today in Nature, reveals the hidden benefits of weight loss on fat tissue.
A better understanding of how weight loss leads to health improvements at a molecular level could help inform the development of therapies for diseases such as type 2 diabetes in the future.
A better understanding of how weight loss leads to health improvements at a molecular level could help inform the development of therapies for diseases such as type 2 diabetes in the future.
Still time to apply for the MRC LMS Emerging Innovators Fellowship for scientists of Black heritage!!!
There's still time to apply for an Emerging Innovators Fellowship for scientists of Black heritage!
If you’re ready to take the next step in your career and make an impact in the world of biomedical research, we encourage you to apply.
Applications close 11 May 2025.
Find out more 👇
If you’re ready to take the next step in your career and make an impact in the world of biomedical research, we encourage you to apply.
Applications close 11 May 2025.
Find out more 👇
Emerging Innovators Fellowship - MRC Laboratory of Medical Sciences
The Emerging Innovators Fellowship is a new 3-year fully-funded postdoctoral fellowship for scientists from Black Heritage Backgrounds.
lms.mrc.ac.uk
May 5, 2025 at 1:25 PM
Still time to apply for the MRC LMS Emerging Innovators Fellowship for scientists of Black heritage!!!
📢To all postdocs. Are you ready to start your semi-independent career? The BBSRC Fellowship call is open. We may host you if you work at the interface of DNA replication/chromatin biology/cancer and like to use protein biochemistry, genomics, cryo-EM, AlphaFold, MD... www.ukri.org/opportunity/...
2024 BBSRC Fellowships scheme
Apply for funding to carry out independent research within a host laboratory and gain leadership skills.
www.ukri.org
February 24, 2025 at 9:01 AM
📢To all postdocs. Are you ready to start your semi-independent career? The BBSRC Fellowship call is open. We may host you if you work at the interface of DNA replication/chromatin biology/cancer and like to use protein biochemistry, genomics, cryo-EM, AlphaFold, MD... www.ukri.org/opportunity/...
Reposted by Christian Speck
700,000 women are to be recruited to take part in an NHS AI breast cancer screening trial in England. Five different AI platforms will be tested across 30 sites from April to see if the technology can speed up diagnosis as well as free up radiologists.
www.bbc.com/news/article...
www.bbc.com/news/article...
Major breast cancer screening AI trial to begin - BBC News
Almost 700,000 women to be recruited to study as government fires starting gun on cancer strategy.
www.bbc.com
February 4, 2025 at 7:48 AM
700,000 women are to be recruited to take part in an NHS AI breast cancer screening trial in England. Five different AI platforms will be tested across 30 sites from April to see if the technology can speed up diagnosis as well as free up radiologists.
www.bbc.com/news/article...
www.bbc.com/news/article...
Reposted by Christian Speck
Excited to share our preprint reporting a completely new approach to study kinase signaling: ProKAS.
ProKAS is based on a tandem array of peptide sensors with barcodes for multiplexed, spatial and kinetic applications.
We applied it to DDR kinases. Please share.
www.biorxiv.org/content/10.1...
ProKAS is based on a tandem array of peptide sensors with barcodes for multiplexed, spatial and kinetic applications.
We applied it to DDR kinases. Please share.
www.biorxiv.org/content/10.1...
December 17, 2024 at 2:10 PM
Excited to share our preprint reporting a completely new approach to study kinase signaling: ProKAS.
ProKAS is based on a tandem array of peptide sensors with barcodes for multiplexed, spatial and kinetic applications.
We applied it to DDR kinases. Please share.
www.biorxiv.org/content/10.1...
ProKAS is based on a tandem array of peptide sensors with barcodes for multiplexed, spatial and kinetic applications.
We applied it to DDR kinases. Please share.
www.biorxiv.org/content/10.1...
I was waiting for that...
New AI system designs proteins that successfully bind to target molecules, with potential for advancing drug design, disease understanding and a system for designing novel, high-strength protein binders to serve as building blocks for biological and health research.
deepmind.google/discover/blo...
deepmind.google/discover/blo...
AlphaProteo generates novel proteins for biology and health research
New AI system designs proteins that successfully bind to target molecules, with potential for advancing drug design, disease understanding and more.
deepmind.google
December 7, 2024 at 2:38 PM
I was waiting for that...
Reposted by Christian Speck
The Baker Lab (@uwproteindesign.bsky.social) recently hosted this powerful webinar on computational #proteindesign. Take a journey through the history of this groundbreaking field, guided by some of the greats! 🧬🧶 #alphafold #proteomics #proteinscience www.youtube.com/live/BuJGTn7...
YouTube
Share your videos with friends, family, and the world
www.youtube.com
November 25, 2024 at 9:07 PM
The Baker Lab (@uwproteindesign.bsky.social) recently hosted this powerful webinar on computational #proteindesign. Take a journey through the history of this groundbreaking field, guided by some of the greats! 🧬🧶 #alphafold #proteomics #proteinscience www.youtube.com/live/BuJGTn7...
Reposted by Christian Speck
📢 Interested in chromosomes and microbes thriving at the edge of life?PhD project in York-UK on chromosome segregation in #Archaea.
Supervised by me, @Steve Quinn & @georgerheath.bsky.social
www.findaphd.com/phds/project...
Open to Applicants Worldwide!
📅 January 6, 2025
#microsky #archaeasky
Supervised by me, @Steve Quinn & @georgerheath.bsky.social
www.findaphd.com/phds/project...
Open to Applicants Worldwide!
📅 January 6, 2025
#microsky #archaeasky
November 23, 2024 at 1:10 PM
📢 Interested in chromosomes and microbes thriving at the edge of life?PhD project in York-UK on chromosome segregation in #Archaea.
Supervised by me, @Steve Quinn & @georgerheath.bsky.social
www.findaphd.com/phds/project...
Open to Applicants Worldwide!
📅 January 6, 2025
#microsky #archaeasky
Supervised by me, @Steve Quinn & @georgerheath.bsky.social
www.findaphd.com/phds/project...
Open to Applicants Worldwide!
📅 January 6, 2025
#microsky #archaeasky