Statistical Physics of Cells and Genomes
banner
spcggroup.bsky.social
Statistical Physics of Cells and Genomes
@spcggroup.bsky.social
BlueSky account of the scientific group Statistical Physics of Cells and Genomes (SPCG), IFOM and U Milan. Principal Investigator (PI) Marco Cosentino Lagomarsino (MCL).
http://spcg.unimi.it/
Our group has a SEMM PhD opening in single-cell dynamics and cancer persistence:

www.semm.it/sites/defaul...

We seek outstanding candidates with cell biology expertise and practical experience in microscopy; physics&engineering backgrounds welcome.

Apply here
www.semm.it/education/ap...
August 1, 2025 at 6:02 AM
Great fun and great science at QMPE 2025 in Shenzhen! www.qmpe.net
May 18, 2025 at 12:20 PM
Just out on bioRxiv - spcg collab with Piel lab: growing mammalian cells use two independent systems — one controlling volume, one driving protein synthesis — to control macromolecular density.

Together, they restore dry mass density homeostasis.

www.biorxiv.org/content/10.1...
April 25, 2025 at 3:10 PM
Spcg preprint with Bertotti lab and @litinice.bsky.social. It took >5y but proud to say it works—and we know why and how. μSeq infers mutation rates from deep sequencing of single clonal expansions, >10x faster than MALs. Validated in cancer organoids and in yeast.

tinyurl.com/4jmk3tkh
April 23, 2025 at 9:19 AM
New spcg preprint with Bokinsky lab (Milan Lacassin), by Andrea Ripamonti. We model the competition for transcriptional resources, and explain new data on E. coli’s second messengers ppGpp & cAMP reshaping gene expression globally.

www.biorxiv.org/content/10.1...
April 21, 2025 at 8:48 AM