Sofi Quinodoz
@sofiquinodoz.bsky.social
Assistant Professor at Johns Hopkins School of Medicine, HHMI Hanna H. Gray Fellow; Studying RNA and DNA organization in nuclear bodies and the cell with SPRITE/genomics/microscopy tools. Postdoc in Brangwynne Lab @Princeton. Ph.D. in Guttman Lab @Caltech
Reposted by Sofi Quinodoz
Nature research paper: Mapping and engineering RNA-driven architecture of the multiphase nucleolus
https://go.nature.com/44Tib11
https://go.nature.com/44Tib11
Mapping and engineering RNA-driven architecture of the multiphase nucleolus - Nature
Spatially segregated rRNA processing dictates nucleolar morphology and drives outward progression of pre-ribosomal RNA through nucleolar phases.
go.nature.com
July 8, 2025 at 8:41 PM
Nature research paper: Mapping and engineering RNA-driven architecture of the multiphase nucleolus
https://go.nature.com/44Tib11
https://go.nature.com/44Tib11
Reposted by Sofi Quinodoz
Combining sequencing and imaging, @brangwynnelab.bsky.social maps the spatiotemporal dynamics of rRNA processing, demonstrating how rRNA serves as both a scaffold and a substrate for the nucleolus—a multiphase, liquid-like structure. 🧪 🧬
Mapping and engineering RNA-driven architecture of the multiphase nucleolus - Nature
Spatially segregated rRNA processing dictates nucleolar morphology and drives outward progression of pre-ribosomal RNA through nucleolar phases.
www.nature.com
July 14, 2025 at 2:06 PM
Combining sequencing and imaging, @brangwynnelab.bsky.social maps the spatiotemporal dynamics of rRNA processing, demonstrating how rRNA serves as both a scaffold and a substrate for the nucleolus—a multiphase, liquid-like structure. 🧪 🧬