Sofie Lundgren
@sofielundgren.bsky.social
M.D./Ph.D at the University of Helsinki. Hematology, immunology, rogue T cells, somatic mutations.
Excited to share our work on T&NK cells in autoimmunity, now out in SciTranslMed! www.science.org/doi/10.1126/...
We explored cells driving autoimmunity, searched for pathogenic TCRs & used single-cell seq in cohort of >200 pts to track them in co-culture with target cells.
1/
We explored cells driving autoimmunity, searched for pathogenic TCRs & used single-cell seq in cohort of >200 pts to track them in co-culture with target cells.
1/
Single-cell analysis of aplastic anemia reveals a convergence of NK and NK-like CD8+ T cells with a disease-associated TCR signature
NK cells and CD8+ TEMRA cells expressing NK receptors and disease-associated T cell receptors may drive autoimmunity in aplastic anemia.
www.science.org
February 28, 2025 at 6:30 AM
Excited to share our work on T&NK cells in autoimmunity, now out in SciTranslMed! www.science.org/doi/10.1126/...
We explored cells driving autoimmunity, searched for pathogenic TCRs & used single-cell seq in cohort of >200 pts to track them in co-culture with target cells.
1/
We explored cells driving autoimmunity, searched for pathogenic TCRs & used single-cell seq in cohort of >200 pts to track them in co-culture with target cells.
1/