Dan Sloan
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sloanevolab.bsky.social
Dan Sloan
@sloanevolab.bsky.social
Molecular Evolutionary Biologist. Professor at Colorado State University Department of Biology. Personal account. Opinions my own (as if anyone else would want them).

https://sites.google.com/site/danielbsloan
Pre-Thanksgiving preprint! Check out our first look at the proteomics of the wacky mitochondria of Silene conica and their translation machinery. Fun project with @jumpinggenomes.bsky.social, Amanda Broz, and Ryan Stikeleather!

www.biorxiv.org/content/10.1...
November 26, 2025 at 4:06 PM
Some slick mito gear hand made by one of our lab alums!
October 28, 2025 at 6:37 PM
New preprint on the role of MutS2 genes in rescuing stalled/collided ribosomes in chloroplasts, led by Amanda Broz and many other contributors from the lab. Never expected to go down this road when we started working on plant MutS2 years ago. Feedback appreciated!

www.biorxiv.org/content/10.1...
September 8, 2025 at 7:49 PM
On the same page there!
September 2, 2025 at 12:32 AM
Yes. Mine are missing too.
January 29, 2025 at 2:03 PM
Hi Lynda! Wish we were talking Silene and not this! Again, def not an expert and the word of PO would be much better, but a reimbursement model is what I've always understood from sponsored programs, and it's consistent with what our internal accounting system shows. e.g. an NSF standard grant...
January 29, 2025 at 2:08 AM
Check out our new preprint in which we use Arabidopsis mutation accumulation lines to quantify just how important the enigmatic plant MSH1 gene is for maintaining low mito and plastid mutation rates. So many mutations detected in msh1 lines!

Feedback appreciated!

www.biorxiv.org/content/10.1...
January 12, 2025 at 6:27 PM
Second paper from the lab out today (woohoo!). This one led by Rachael DeTar. Check out what happens to mito+plastid translation machinery in plants that have lost photosynthesis!

Published in @pnas.org: www.pnas.org/doi/10.1073/...

Also available on bioRxiv: www.biorxiv.org/content/10.1...
December 18, 2024 at 7:26 PM
Happy to share our collaborative review on the expansion of the MutS gene family in plants and all the cool (and in some cases still unknown) roles of these genes. Now published in @theplantcell.bsky.social!

doi.org/10.1093/plce...
December 18, 2024 at 3:45 PM
We used specialized RNA sequencing techniques in the coralroot orchid and found that the fungal protein-coding genes have all been pseudogenized but some tRNA genes are expressed, processed, and charged with amino acids.

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November 21, 2024 at 8:37 PM
Previous studies (Sinn and Barrett 2020; Valencia-D et al. 2023) documented this ancient horizontal gene transfer, but it’s been unclear whether any of this DNA regions is functional.

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November 21, 2024 at 8:37 PM
Did you know that orchids have a big chunk of fungal mtDNA stuck in their own mitochondrial genomes?? In this new preprint, we found that fungal-derived tRNAs are functional in the orchid mitochondria.

www.biorxiv.org/content/10.1...

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November 21, 2024 at 8:37 PM
Haven't been posting on this platform yet, but it seems like a great time to start sharing our lab's work here. Check out our new paper, investigating aminoacylation and base modifications in plant tRNAs -- a great collaboration with the Sanchez-Puerta lab!

onlinelibrary.wiley.com/doi/10.1111/...
November 18, 2024 at 2:06 PM