Satoshi Koyama
@skoyama.bsky.social
Assist. Director of Bioinformatics | MGB Personalized Medicine
Investigator, Cardiovascular Research Center | Massachusetts General Hospital Member of the Faculty | Harvard Medical School
Interested in Cardiovascular Genetics and Personalized Medicine 🧬👨💻
Investigator, Cardiovascular Research Center | Massachusetts General Hospital Member of the Faculty | Harvard Medical School
Interested in Cardiovascular Genetics and Personalized Medicine 🧬👨💻
Heading to #ASHG2025 ✈️🚢🚎?
We’ll present the latest CAD GWAS updates from CARDIoGRAMplusC4D (cardiogramplusc4d.xn--org)would-389d love to see you there!
📅 Saturday, Oct 18, 9:15–9:30 AM ET
📍 Room 253ABC (Level 2)
We’ll present the latest CAD GWAS updates from CARDIoGRAMplusC4D (cardiogramplusc4d.xn--org)would-389d love to see you there!
📅 Saturday, Oct 18, 9:15–9:30 AM ET
📍 Room 253ABC (Level 2)
October 10, 2025 at 1:47 PM
Heading to #ASHG2025 ✈️🚢🚎?
We’ll present the latest CAD GWAS updates from CARDIoGRAMplusC4D (cardiogramplusc4d.xn--org)would-389d love to see you there!
📅 Saturday, Oct 18, 9:15–9:30 AM ET
📍 Room 253ABC (Level 2)
We’ll present the latest CAD GWAS updates from CARDIoGRAMplusC4D (cardiogramplusc4d.xn--org)would-389d love to see you there!
📅 Saturday, Oct 18, 9:15–9:30 AM ET
📍 Room 253ABC (Level 2)
If you’re interested in this topic and attending #ASHG2025
@geneticssociety.bsky.social in Boston, we’d love to see you at our talk!
📅 Sat, Oct 18, 9:15–9:30 AM ET
📍 Room 253ABC (Level 2)
@geneticssociety.bsky.social in Boston, we’d love to see you at our talk!
📅 Sat, Oct 18, 9:15–9:30 AM ET
📍 Room 253ABC (Level 2)
October 2, 2025 at 12:57 AM
If you’re interested in this topic and attending #ASHG2025
@geneticssociety.bsky.social in Boston, we’d love to see you at our talk!
📅 Sat, Oct 18, 9:15–9:30 AM ET
📍 Room 253ABC (Level 2)
@geneticssociety.bsky.social in Boston, we’d love to see you at our talk!
📅 Sat, Oct 18, 9:15–9:30 AM ET
📍 Room 253ABC (Level 2)
Excited to share that I’m launching a Computational Genetics Lab spanning MGB Personalized Medicine, Cardiovascular Research Center at MGH, @harvardmed.bsky.social, and @broadinstitute.org. Our research focuses on the genetics of common diseases, with a particular emphasis on cardiovascular disease.
October 2, 2025 at 12:57 AM
Excited to share that I’m launching a Computational Genetics Lab spanning MGB Personalized Medicine, Cardiovascular Research Center at MGH, @harvardmed.bsky.social, and @broadinstitute.org. Our research focuses on the genetics of common diseases, with a particular emphasis on cardiovascular disease.
6/ Interestingly, when we focused on individual variants within established cholesterol-regulating pathways (LDLR, PCSK9, HMGCR, NPC1L1), we did not find strong evidence for pathway-specific effects.
January 15, 2025 at 7:23 PM
6/ Interestingly, when we focused on individual variants within established cholesterol-regulating pathways (LDLR, PCSK9, HMGCR, NPC1L1), we did not find strong evidence for pathway-specific effects.
5/ What did we find?
Higher genetic LDL-C is associated with a lower risk of T2D 📉
Lower genetic LDL-C is associated with a higher risk of T2D 📈
This effect was observed across various genetic predispositions.
Higher genetic LDL-C is associated with a lower risk of T2D 📉
Lower genetic LDL-C is associated with a higher risk of T2D 📈
This effect was observed across various genetic predispositions.
January 15, 2025 at 7:22 PM
5/ What did we find?
Higher genetic LDL-C is associated with a lower risk of T2D 📉
Lower genetic LDL-C is associated with a higher risk of T2D 📈
This effect was observed across various genetic predispositions.
Higher genetic LDL-C is associated with a lower risk of T2D 📉
Lower genetic LDL-C is associated with a higher risk of T2D 📈
This effect was observed across various genetic predispositions.