Silvestre Roig Lab
@silvestreroiglab.bsky.social
We are interested in everything related to neutrophils! focused on understanding the pathophysiology of neutrophil-driven vascular damage, the importance of neutrophil diversity, and its modulation by environmental factors.
University of Münster, Germany
University of Münster, Germany
New review from our lab! We show how ontogeny lays the foundation for neutrophils to develop functional heterogeneity. Thrilled to contribute to the ‘New Paradigm of Neutrophils’ special issue in Experimental Hematology. www.sciencedirect.com/science/arti...
Ontogenetic drivers of neutrophil heterogeneity
Neutrophil development is a tightly regulated, multi-step process involving stem cell commitment, differentiation, and maturation in the bone marrow. …
www.sciencedirect.com
August 12, 2025 at 3:05 PM
New review from our lab! We show how ontogeny lays the foundation for neutrophils to develop functional heterogeneity. Thrilled to contribute to the ‘New Paradigm of Neutrophils’ special issue in Experimental Hematology. www.sciencedirect.com/science/arti...
Congrats David! Happy to see it out!! Amazing work!
💥 A gut microbe metabolite that drives #atherosclerosis?
Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol.
🧪 We show the pathway—and how to block it.
nature.com/articles/s41... #OpenAccess at
@Nature
@CNIC_CARDIO
#CVD #immunosky #cardiosky #microbiomesky
Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol.
🧪 We show the pathway—and how to block it.
nature.com/articles/s41... #OpenAccess at
@Nature
@CNIC_CARDIO
#CVD #immunosky #cardiosky #microbiomesky
Imidazole propionate is a driver and therapeutic target in atherosclerosis - Nature
Imidazole propionate produced by gut microbiota is associated with atherosclerosis in mouse models and in humans, and causes the development of atherosclerosis through activation of the imidazoline-1 ...
nature.com
July 16, 2025 at 6:22 PM
Congrats David! Happy to see it out!! Amazing work!
Stanley Huang told us about metabolic regulation of macrophages and Roser Vento gave us a great talk on spatial analysis of macrophages in reproductive tissues! What an amazing end of session. #EPW2025 #immunosky
March 29, 2025 at 10:02 PM
Stanley Huang told us about metabolic regulation of macrophages and Roser Vento gave us a great talk on spatial analysis of macrophages in reproductive tissues! What an amazing end of session. #EPW2025 #immunosky
Beautiful work on Kupffer cells and LAMs during liver damage by Federico de Pinto! #EPW2025 #immunosky @charlottelscott.bsky.social
March 28, 2025 at 4:33 PM
Beautiful work on Kupffer cells and LAMs during liver damage by Federico de Pinto! #EPW2025 #immunosky @charlottelscott.bsky.social
Mind blowing talk by Alejo Fraticelli! New techniques to understand HSC phylogeny! @alejofraticelli.bsky.social #EPW2025 #immunesky
March 28, 2025 at 4:28 PM
Mind blowing talk by Alejo Fraticelli! New techniques to understand HSC phylogeny! @alejofraticelli.bsky.social #EPW2025 #immunesky
Time matters in Lung Cancer! And neutrophils (of course) are the main suspects! Great talk by Alba de Juan @casanova-acebes.bsky.social lab. #EPW2025 #immunosky
March 28, 2025 at 2:22 PM
Time matters in Lung Cancer! And neutrophils (of course) are the main suspects! Great talk by Alba de Juan @casanova-acebes.bsky.social lab. #EPW2025 #immunosky
Last flash talk by Lucia de Prado Rivas on mTorc1 in macrophages and atherosclerosis. #EPW2025 #immunosky
March 28, 2025 at 2:02 PM
Last flash talk by Lucia de Prado Rivas on mTorc1 in macrophages and atherosclerosis. #EPW2025 #immunosky
Mathis Richter shows us the importance of preNEUs in myocardial infarction! #EPW2025 #immunosky @mathisrichter.bsky.social
March 28, 2025 at 10:56 AM
Mathis Richter shows us the importance of preNEUs in myocardial infarction! #EPW2025 #immunosky @mathisrichter.bsky.social
María Luisa Gil on Trained neutrophils in infection! #EPW2025 #immunosky
March 28, 2025 at 10:44 AM
María Luisa Gil on Trained neutrophils in infection! #EPW2025 #immunosky
Third Juan Manuel Lozano-Gil on ninjurins and HSPCs function. #EPW2025 #immunosky
March 28, 2025 at 10:41 AM
Third Juan Manuel Lozano-Gil on ninjurins and HSPCs function. #EPW2025 #immunosky
Second Maria Caffarel with Oncostatin M in tumor immunity. #EPW2025 #immunosky
March 28, 2025 at 10:39 AM
Second Maria Caffarel with Oncostatin M in tumor immunity. #EPW2025 #immunosky
We start the second round of flash talks! First Ioannis Kourtzelis and immune regulation by DEL-1. #EPW2025 #immunosky
March 28, 2025 at 10:07 AM
We start the second round of flash talks! First Ioannis Kourtzelis and immune regulation by DEL-1. #EPW2025 #immunosky
And here the main actor!
March 28, 2025 at 9:37 AM
And here the main actor!
We start the 3rd and final day! #EPW2025 with Venizelos Papayannopoulos and neutrophil heterogeneous anti-microbial activities! #immunosky
March 28, 2025 at 8:33 AM
We start the 3rd and final day! #EPW2025 with Venizelos Papayannopoulos and neutrophil heterogeneous anti-microbial activities! #immunosky
Last talk of the day: Balázs Enyedi illuminating us on neutrophil chemoattractants! #EPW2025 #immunosky
March 27, 2025 at 4:32 PM
Last talk of the day: Balázs Enyedi illuminating us on neutrophil chemoattractants! #EPW2025 #immunosky
Short talk by Cassia Michael from @sdeoliveira.bsky.social lab! Learning the role of neutrophils during poly traumatic injury! So cool! #EPW2025 #immunosky
March 27, 2025 at 4:13 PM
Short talk by Cassia Michael from @sdeoliveira.bsky.social lab! Learning the role of neutrophils during poly traumatic injury! So cool! #EPW2025 #immunosky
We start the 3rd session of the #EPW2025 on Phagocytes in Motion! With the one and only Sussan Nourshargh! #immunosky
March 27, 2025 at 1:23 PM
We start the 3rd session of the #EPW2025 on Phagocytes in Motion! With the one and only Sussan Nourshargh! #immunosky
Short talk by Kami Pekayvaz on macrophages associated with sympathetic nerves! #EPW2025 #TRR332 #immunosky
March 27, 2025 at 10:59 AM
Short talk by Kami Pekayvaz on macrophages associated with sympathetic nerves! #EPW2025 #TRR332 #immunosky
Flash talks round 1! Amazing teasers for their posters! #EPW2025 #immunosky
March 27, 2025 at 10:18 AM
Flash talks round 1! Amazing teasers for their posters! #EPW2025 #immunosky
Reposted by Silvestre Roig Lab
@udalovalab.bsky.social on stage! VSIG4+ aquaporin1 macs take care of your moves...macs in other difficult niches to look or isolate like joints...impressive imaging!
March 27, 2025 at 9:17 AM
@udalovalab.bsky.social on stage! VSIG4+ aquaporin1 macs take care of your moves...macs in other difficult niches to look or isolate like joints...impressive imaging!
We continue with neutrophils and hypoxia! Short talk by Manuel Sanchez Garcia. #EPW2025 @walmsley-lab.bsky.social lab. #immunosky
March 27, 2025 at 8:32 AM
We continue with neutrophils and hypoxia! Short talk by Manuel Sanchez Garcia. #EPW2025 @walmsley-lab.bsky.social lab. #immunosky
Second day! And we start with @sancholab.bsky.social also co-organizer of #EPW2025. We will know more about trained immunity and metabolic reprogramming of myeloid cells!
March 27, 2025 at 7:37 AM
Second day! And we start with @sancholab.bsky.social also co-organizer of #EPW2025. We will know more about trained immunity and metabolic reprogramming of myeloid cells!
So happy to have you! We learned so much about macrophages! Thanks!
Thanks to the organizers @sancholab.bsky.social @casanova-acebes.bsky.social & Carlos Silvestre for giving me the opportunity to kick-off this fantastic meeting #EPW2025
What a day for #macrophage lovers!
What a day for #macrophage lovers!
#immunosky #epw2025 Great novel work by @masslab.bsky.social on the impact of micro and nanoplastics in macrophages! Large effect on liver Kupffer cells, while other organs are more protected. Read more here!!!
sciety.org/articles/act...
sciety.org/articles/act...
March 26, 2025 at 9:18 PM
So happy to have you! We learned so much about macrophages! Thanks!
And now... Philipp Henneke! Talking about immune development during early-life #EPW2025 #immunosky
March 26, 2025 at 4:31 PM
And now... Philipp Henneke! Talking about immune development during early-life #EPW2025 #immunosky